Article
Plant Sciences
Anislada Santibanez, Maribel Herrera-Ruiz, Manases Gonzalez-Cortazar, Pilar Nicasio-Torres, Ashutosh Sharma, Enrique Jimenez-Ferrer
Summary: Tagetes lucida is widely used in folk medicine for diseases related to the central nervous system and inflammation, with coumarins being key compounds. A method for simultaneous quantification of coumarins was established, showing increased concentrations in the brain in a neuroinflammation model, indicating potential therapeutic effects.
Article
Biochemistry & Molecular Biology
Xiuqiong Huang, Wei Gao, Xuan Yun, Zhixing Qing, Jianguo Zeng
Summary: This study found that quercetagetin (QG) extracted from marigold has high antioxidant activity and can effectively inhibit the oxidation of soybean oil, including the reduction of aldehydes and ketones. The results suggest that QG could be a potential natural antioxidant with applications in the food industry.
Article
Plant Sciences
Carlos Fernandez-Galleguillos, Felipe Jimenez-Aspee, Daniel Mieres-Castro, Yeray A. Rodriguez-Nunez, Margarita Gutierrez, Luis Guzman, Javier Echeverria, Claudia Sandoval-Yanez, Oscar Forero-Doria
Summary: This study aimed to identify the phenolic profile and composition of three native species used in traditional medicine in northern Chile and evaluate their inhibitory effects against acetylcholinesterase and butyrylcholinesterase. Polyphenolic enriched-extracts were prepared and analyzed, and 30 phenolic compounds were identified and quantified. Tagetes multiflora showed the highest inhibitory activity, but weaker than the control. Molecular docking analysis was conducted to understand the interactions between cholinesterase enzymes and the main phenolics in T. multiflora.
Article
Chemistry, Organic
You Wu, Shuqi Wang, Bo Peng, Jie Cen, Yongping Yu, Wenteng Chen
Summary: In this study, a Lewis acid-catalyzed tandem reaction was developed for the facile construction of the thiophene ring using ketene 1,3-dithietanes as sulfur-containing synthons. The reaction involved nucleophilic addition/C-S cleavage/intramolecular annulation steps, and showed good functional group tolerance and mild reaction conditions. The possible mechanisms were proposed.
ORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Chemistry, Multidisciplinary
Arup Mondal, Manuel van Gemmeren
Summary: Alkynes are important motifs in organic synthesis due to their presence in natural products and bioactive molecules. The method of inserting alkynes into (hetero)arenes relies heavily on the regioselectivity of the halogenation step, and can achieve selective alkynylation of thiophenes. The developed palladium-catalyzed C-H activation/alkynylation of thiophenes allows for regiodivergent reactions and late-stage modifications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Heng Liu, Gu-Cheng He, Chao-Yang Zhao, Xiang-Xin Zhang, Ding-Wei Ji, Yan-Cheng Hu, Qing-An Chen
Summary: This study demonstrates a redox-divergent construction of dihydrothiophenes, thiophenes, and bromothiophenes using allylic alcohols, DMSO, and HBr. The selectivity of the reaction can be manipulated by controlling the dosage of DMSO and HBr. The products show synthetic potentials as platform molecules for the preparation of various bioactive and functional molecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biochemical Research Methods
Christina Vanhinsbergh, Elliot C. Hook, Nicola Oxby, Mark J. Dickman
Summary: In this study, a method for analyzing closely related oligonucleotides and oligonucleotide manufacturing impurities was developed by optimizing different 1D-LC methods and coupling two orthogonal chromatographic modes in a 2D-LC workflow. The method resulted in an increased orthogonality and a reduction in co-elution, and the application of a UV based reference mapping strategy reduced the analytical complexity and reliance on mass-based detection methods.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Article
Plant Sciences
Y. Q. Zha, K. K. Zhang, F. Pan, X. Liu, S. M. Han, P. Guan
Summary: Phytochelatins (PCs) are important for plants to resist heavy metal stress, with TpPCS1 gene playing a key role in Peacock grass and enhancing cadmium enrichment in roots.
Article
Chemistry, Organic
Georgyi Koidan, Anastasiya Hurieva, Serhii Zahorulko, Alexander Zadorozhny, Viacheslav Lysenko, Tetiana Shvydenko, Eduard B. Rusanov, Aleksandr Kostyuk
Summary: The reaction of silylformamidine with various halo- and ethoxycarbonyl substituted thiophenes was studied. It proceeded via C-H bond insertion of the nucleophilic diaminocarbene that exists in an equilibrium with silylformamidine affording aminals. The reaction proceeded more readily at the 2(5)-position compared to the 3(4) one. The number of halogens at the thiophenes markedly influences the reaction. The more halogens, the higher the reaction rate. Even one electron acceptor group at the thiophene ring is enough to promote the reaction. As a rule, the reaction does not require solvents or catalysts. Hydrolyses of the aminals provides a novel convenient approach to substituted thiophene aldehydes.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Khaled Youssef, Magali Allain, Thomas Cauchy, Frederic Gohier
Summary: 2-Bromo, 3-bromothiophene, 2,5-dibromothiophene, 3,4-dibromothiophene, and perbrominated thiophene were oxidized under different conditions to form thiophene S,S-dioxide. Depending on the substitution, sulfone was obtained when the hindered thiophene was used. However, monosubstituted thiophenes could not be transformed into sulfone due to the reactivity of the sulfoxide intermediate, which led to dimerization. The structures were confirmed through the obtaining of crystals. The oxidation of 3,4-dibromothiophene could either result in the formation of cycloadduct or the isolation of sulfone, which could further evolve into benzothiophene sulfone.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Agricultural Engineering
B. Weber, M. D. Duran-Garcia, C. Froehlich
Summary: Thermal analysis can predict biogas/methane yields and the biodegradability of biomass affects these yields. This study developed a bioconversion model based on thermogravimetry and used a regression model to predict biogas and methane yields for different substrates. The results showed that this prediction technique has good accuracy and can be an alternative to other models.
BIORESOURCE TECHNOLOGY
(2023)
Article
Chemistry, Physical
Raffaella Mancuso, Romina Strangis, Ida Ziccarelli, Nicola Della Ca, Bartolo Gabriele
Summary: The study reports the first example of a palladium-catalyzed oxidative carbonylative S-cyclization process conducted under aerobic conditions, leading to the successful synthesis of thiophene-3-carboxylic esters in one step. By utilizing specific substrates and reaction conditions, the transformation was achieved efficiently.
JOURNAL OF CATALYSIS
(2021)
Article
Agriculture, Multidisciplinary
Jiaxin Wang, Zhiming Qi, Chong Wang
Summary: Phosphorus (P) management is crucial for environmental protection as inappropriate application can cause water pollution. However, conflicting experimental results make it difficult to draw general conclusions, and there is a lack of comprehensive analysis on the impact of P management on crop yields. This study conducted a meta-analysis to assess the effectiveness of different P management practices on reducing soil P loss and their impact on crop yields. The results indicate that the most effective practices for reducing soil P loss may not necessarily lead to the greatest improvement in crop yield. Efficient irrigation, crop straw return, buffer strip, and intercropping were found to be the most effective in reducing soil P loss, while soil amendment, intercropping, and conservative practices showed the largest increase in crop yields.
AGRICULTURE ECOSYSTEMS & ENVIRONMENT
(2023)
Article
Agronomy
Etiendem Achankeng, Wim Cornelis
Summary: This study investigates the impact of ridge tillage (RT) and strip tillage (ST) on crop yields in Europe in comparison with no-till (NT) and conventional tillage (CT). The results show that, on average, NT leads to a 5.1% reduction in crop yields, while RT and ST each result in a 5% increase in crop yield over CT.
FIELD CROPS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Simon Cromwell, Randy Sutio, Changhe Zhang, Georgina K. Such, David W. Lupton
Summary: In this study, a reaction cascade involving the addition of C1-pyridinium enolate to thiocarbonyl compounds was reported, leading to the synthesis of a range of dihydrothiophenes and dihydrothiopyrans. Mechanistic investigations and experimental evidence supported the involvement of an activated acid intermediate and turnover limiting cyclization in the reaction pathway, with subsequent formation of β-thiolactone regenerating the catalyst.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Agriculture, Multidisciplinary
Raffaella Di Silvestro, Alessandro Di Loreto, Sara Bosi, Valeria Bregola, Ilaria Marotti, Stefano Benedettelli, Antonio Segura-Carretero, Giovanni Dinelli
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2017)
Article
Food Science & Technology
Patrizia Alvisi, Luigia De Fazio, Maria Chiara Valerii, Elena Cavazza, Angela Salerno, Doriana Lacorte, Giovanni Dinelli, Enzo Spisni
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2017)
Article
Agriculture, Multidisciplinary
A. Di Loreto, R. Di Silvestro, G. Dinelli, V. Bregola, V. Stenico, R. E. Sferrazza, I. Marotti, R. Quinn, S. Bosi
JOURNAL OF AGRICULTURAL SCIENCE
(2017)
Article
Food Science & Technology
Danielle Taneyo Saa, Raffaella Di Silvestro, Giovanni Dinelli, Andrea Gianotti
LWT-FOOD SCIENCE AND TECHNOLOGY
(2017)
Article
Food Science & Technology
Morena Gabriele, Stefania Frassinetti, Leonardo Caltavuturo, Lidia Montero, Giovanni Dinelli, Vincenzo Longo, Diana Di Gioia, Laura Pucci
JOURNAL OF FUNCTIONAL FOODS
(2017)
Article
Agriculture, Multidisciplinary
A. Di Loreto, R. Di Silvestro, G. Dinelli, V. Bregola, V. Stenico, R. E. Sferrazza, I. Marotti, R. Quinn, S. Bosi
JOURNAL OF AGRICULTURAL SCIENCE
(2017)
Article
Soil Science
L. Vittori Antisari, S. Carbone, S. Bosi, A. Gatti, G. Dinelli
APPLIED SOIL ECOLOGY
(2018)
Article
Biochemical Research Methods
Alessandro Di Loreto, Sara Bosi, Lidia Montero, Valeria Bregola, Ilaria Marotti, Rocco Enrico Sferrazza, Giovanni Dinelli, Miguel Herrero, Alejandro Cifuentes
Article
Environmental Sciences
Simona Panzacchi, Daniele Mandrioli, Fabiana Manservisi, Luciano Bua, Laura Falcioni, Marcella Spinaci, Giovanna Galeati, Giovanni Dinelli, Rossella Miglio, Alberto Mantovani, Stefano Lorenzetti, Jianzhong Hu, Jia Chen, Melissa J. Perry, Philip J. Landrigan, Fiorella Belpoggi
ENVIRONMENTAL HEALTH
(2018)
Article
Biochemical Research Methods
Roberto Gotti, Elisa Amadesi, Jessica Fiori, Sara Bosi, Valeria Bregola, Ilaria Marotti, Giovanni Dinelli
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Food Science & Technology
Sara Bosi, Jessica Fiori, Giovanni Dinelli, Neil Rigby, Emanuela Leoncini, Cecilia Prata, Valeria Bregola, Ilaria Marotti, Roberto Gotti, Marina Naldi, Luca Massaccesi, Marco Malaguti, Paul Kroon, Silvana Hrelia
JOURNAL OF FOOD SCIENCE
(2018)
Article
Food Science & Technology
Danielle Taneyo Saa, Raffaella Di Silvestro, Lorenzo Nissen, Giovanni Dinelli, Andrea Gianotti
LWT-FOOD SCIENCE AND TECHNOLOGY
(2018)
Article
Nutrition & Dietetics
Francesca Gaggia, Loredana Baffoni, Michele Galiano, Dennis Sandris Nielsen, Rasmus Riemer Jakobsen, Josue Leonardo Castro-Mejia, Sara Bosi, Francesca Truzzi, Federica Musumeci, Giovanni Dinelli, Diana Di Gioia
Article
Nutrition & Dietetics
Arrigo F. G. Cicero, Federica Fogacci, Maddalena Veronesi, Elisa Grandi, Giovanni Dinelli, Silvana Hrelia, Claudio Borghi
Article
Biotechnology & Applied Microbiology
Erwin Strahsburger, Ana Maria Lopez de lacey, Ilaria Marotti, Diana DiGioia, Bruno Biavati, Giovanni Dinelli
ELECTRONIC JOURNAL OF BIOTECHNOLOGY
(2017)