The Influence of Adnectin Binding on the Extracellular Domain of Epidermal Growth Factor Receptor

Fast Photochemical Oxidation of Proteins (FPOP) Maps the Epitope of EGFR Binding to Adnectin

(2014) Yuetian Yan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Architecture and Membrane Interactions of the EGF Receptor

(2013) Anton Arkhipov et al.   CELL

Investigating Monoclonal Antibody Aggregation Using a Combination of H/DX-MS and Other Biophysical Measurements

(2013) Roxana E. Iacob et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Analysis of Overlapped and Noisy Hydrogen/Deuterium Exchange Mass Spectra

(2013) Miklos Guttman et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

(2013) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review

(2012) Andrew J. Percy et al.   ANALYTICA CHIMICA ACTA

Accessing the reproducibility and specificity of pepsin and other aspartic proteases

(2012) Joomi Ahn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization

(2012) Yibing Shan et al.   CELL

Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery

(2012) Kamila J. Pacholarz et al.   CHEMICAL SOCIETY REVIEWS

Characterization of epitopes recognized by monoclonal antibodies: experimental approaches supported by freely accessible bioinformatic tools

(2012) Nicola Clementi et al.   DRUG DISCOVERY TODAY

Partial cooperative unfolding in proteins as observed by hydrogen exchange mass spectrometry

(2012) John R. Engen et al.   INTERNATIONAL REVIEWS IN PHYSICAL CHEMISTRY

Hydrogen Exchange Mass Spectrometry: Are We Out of the Quicksand?

(2012) Roxana E. Iacob et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structures of Adnectin/Protein Complexes Reveal an Expanded Binding Footprint

(2012) Vidhyashankar Ramamurthy et al.   STRUCTURE

Epitope Mapping of a 95 kDa Antigen in Complex with Antibody by Solution-Phase Amide Backbone Hydrogen/Deuterium Exchange Monitored by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2011) Qian Zhang et al.   ANALYTICAL CHEMISTRY

Differential hydrogen/deuterium exchange mass spectrometry analysis of protein–ligand interactions

(2011) Michael J Chalmers et al.   Expert Review of Proteomics

ETD in a Traveling Wave Ion Guide at Tuned Z-Spray Ion Source Conditions Allows for Site-Specific Hydrogen/Deuterium Exchange Measurements

(2011) Kasper D. Rand et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding

(2011) Shalini T Low-Nam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence for Increased Exposure of the Notch1 Metalloprotease Cleavage Site upon Conversion to an Activated Conformation

(2011) Kittichoat Tiyanont et al.   STRUCTURE

Ligand docking and binding site analysis with PyMOL and Autodock/Vina

(2010) Daniel Seeliger et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies

(2010) Damian Houde et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

(2010) John Wojcik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Adnectins: engineered target-binding protein therapeutics

(2010) D. Lipovsek   PROTEIN ENGINEERING DESIGN & SELECTION

Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation

(2010) Zhongqi Zhang et al.   PROTEIN SCIENCE

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS

(2009) John R. Engen   ANALYTICAL CHEMISTRY

High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

(2008) Thomas E. Wales et al.   ANALYTICAL CHEMISTRY

Structure-Based View of Epidermal Growth Factor Receptor Regulation

(2008) Kathryn M. Ferguson   Annual Review of Biophysics

Ligand-induced ErbB receptor dimerization

(2008) Mark A. Lemmon   EXPERIMENTAL CELL RESEARCH

Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling

(2008) Benjamin J. Hackel et al.   JOURNAL OF MOLECULAR BIOLOGY

Electron Transfer Dissociation Facilitates the Measurement of Deuterium Incorporation into Selectively Labeled Peptides with Single Residue Resolution

(2008) Martin Zehl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Assessment of the repeatability and reproducibility of hydrogen/deuterium exchange mass spectrometry measurements

(2008) William Burkitt et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY