Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell Death

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

(2014) Ivan KH Poon et al.   eLife

Antifungal activity of plant defensin AFP1 in Brassica juncea involves the recognition of the methyl residue in glucosylceramide of target pathogen Candida albicans

(2013) Yoshifumi Oguro et al.   CURRENT GENETICS

Hypoxia Reduces the Efficiency of Elisidepsin by Inhibiting Hydroxylation and Altering the Structure of Lipid Rafts

(2013) Anna Király et al.   Marine Drugs

Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer

(2012) Melis Kartal Yandım et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Suppression of Glucosylceramide Synthase Restores p53-Dependent Apoptosis in Mutant p53 Cancer Cells

(2011) Y.-Y. Liu et al.   CANCER RESEARCH

Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics

(2011) Alfred H. Merrill   CHEMICAL REVIEWS

ErbB protein modifications are secondary to severe cell membrane alterations induced by elisidepsin treatment

(2011) Tímea Váradi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Irvalec Inserts into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells

(2011) José M. Molina-Guijarro et al.   PLoS One

Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities

(2011) D. S. Palacios et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ceramide galactosyltransferase (UGT8) is a molecular marker of breast cancer malignancy and lung metastases

(2010) P Dziȩgiel et al.   BRITISH JOURNAL OF CANCER

Therapeutic applications of bioactive sphingolipids in hematological malignancies

(2010) Huseyin Atakan Ekiz et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular facets of sphingolipids: Mediators of diseases

(2009) Fatma Betul Kavun Ozbayraktar et al.   Biotechnology Journal

Piercing insights

(2009) Hagan Bayley   NATURE

Pore formation: An ancient yet complex form of attack

(2008) Ioan Iacovache et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer

(2008) Eugen Ruckhäberle et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Studies on anticancer activities of antimicrobial peptides

(2007) David W. Hoskin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES