Hypoxia Reduces the Efficiency of Elisidepsin by Inhibiting Hydroxylation and Altering the Structure of Lipid Rafts

Eicosanoids and Docosanoids in Plasma and Aorta of Healthy and Atherosclerotic Rabbits

(2013) Monika Szklenar et al.   JOURNAL OF VASCULAR RESEARCH

A phase I and pharmacokinetic study of elisidepsin (PM02734) in patients with advanced solid tumors

(2012) R. Salazar et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers

(2012) Lin Guo et al.   JOURNAL OF LIPID RESEARCH

The Effect of Lidocaine · HCl on the Fluidity of Native and Model Membrane Lipid Bilayers

(2012) Jun-Seop Park et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

PM02734 (Elisidepsin) Induces Caspase-Independent Cell Death Associated with Features of Autophagy, Inhibition of the Akt/mTOR Signaling Pathway, and Activation of Death-Associated Protein Kinase

(2011) Yi-He Ling et al.   CLINICAL CANCER RESEARCH

ErbB protein modifications are secondary to severe cell membrane alterations induced by elisidepsin treatment

(2011) Tímea Váradi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Irvalec Inserts into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells

(2011) José M. Molina-Guijarro et al.   PLoS One

Fatty Acid 2-Hydroxylase Mediates Diffusional Mobility of Raft-associated Lipids, GLUT4 Level, and Lipogenesis in 3T3-L1 Adipocytes

(2010) Lin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acid 2-Hydroxylation in mammalian sphingolipid biology

(2009) Hiroko Hama   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cancer Treatments: Can We Find Treasures at the Bottom of the Sea?

(2009) Mariano Provencio et al.   Clinical Lung Cancer

Gangliosides in cell recognition and membrane protein regulation

(2009) Pablo HH Lopez et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular pharmacodynamics of PM02734 (elisidepsin) as single agent and in combination with erlotinib; synergistic activity in human non-small cell lung cancer cell lines and xenograft models

(2009) Yi-He Ling et al.   EUROPEAN JOURNAL OF CANCER

Phase II study of weekly Kahalalide F in patients with advanced malignant melanoma

(2009) Salvador Martín-Algarra et al.   EUROPEAN JOURNAL OF CANCER

Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers

(2009) Jun Yin et al.   FEBS LETTERS

Mutations in the Fatty Acid 2-Hydroxylase Gene Are Associated with Leukodystrophy with Spastic Paraparesis and Dystonia

(2008) Simon Edvardson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Levels of SCS7/FA2H-Mediated Fatty Acid 2-Hydroxylation Determine the Sensitivity of Cells to Antitumor PM02734

(2008) A. B. Herrero et al.   CANCER RESEARCH

Phase I Clinical and Pharmacokinetic Study of Kahalalide F Administered Weekly as a 1-Hour Infusion to Patients with Advanced Solid Tumors

(2008) B. Pardo et al.   CLINICAL CANCER RESEARCH

Making progress against cancer in Europe in 2008

(2008) Tit Albreht et al.   EUROPEAN JOURNAL OF CANCER

Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration

(2008) I. Zoller et al.   JOURNAL OF NEUROSCIENCE

Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

(2007) Michelle A. Digman et al.   BIOPHYSICAL JOURNAL