The effects of haloperidol on microglial morphology and translocator protein levels: An in vivo study in rats using an automated cell evaluation pipeline

Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models

(2018) Toby Pillinger et al.   MOLECULAR PSYCHIATRY

Lower levels of the glial cell marker TSPO in drug-naive first-episode psychosis patients as measured using PET and [11C]PBR28

(2017) K Collste et al.   MOLECULAR PSYCHIATRY

Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization

(2017) O D Howes et al.   Translational Psychiatry

Immune involvement in the pathogenesis of schizophrenia: a meta-analysis on postmortem brain studies

(2017) C F M G van Kesteren et al.   Translational Psychiatry

Microglia and Brain Plasticity in Acute Psychosis and Schizophrenia Illness Course: A Meta-Review

(2017) Livia J. De Picker et al.   Frontiers in Psychiatry

Brain TSPO imaging and gray matter volume in schizophrenia patients and in people at ultra high risk of psychosis: An [ 11 C]PBR28 study

(2017) Sudhakar Selvaraj et al.   SCHIZOPHRENIA RESEARCH

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study

(2016) Peter S. Bloomfield et al.   AMERICAN JOURNAL OF PSYCHIATRY

In vivo imaging of brain microglial activity in antipsychotic-free and medicated schizophrenia: a [11C](R)-PK11195 positron emission tomography study

(2016) S E Holmes et al.   MOLECULAR PSYCHIATRY

Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness

(2016) Marilia A. Calcia et al.   PSYCHOPHARMACOLOGY

In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [11C]DPA-713 PET and analysis of CSF and plasma

(2016) J M Coughlin et al.   Translational Psychiatry

Microglial activation in the rat brain following chronic antipsychotic treatment at clinically relevant doses

(2015) Marie-Caroline Cotel et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Minocycline and Risperidone Prevent Microglia Activation and Rescue Behavioral Deficits Induced by Neonatal Intrahippocampal Injection of Lipopolysaccharide in Rats

(2014) Furong Zhu et al.   PLoS One

Imaging Neuroinflammation in Gray and White Matter in Schizophrenia: An In-Vivo PET Study With [18F]-FEPPA

(2014) M. Kenk et al.   SCHIZOPHRENIA BULLETIN

Reduced Cortical Volume and Elevated Astrocyte Density in Rats Chronically Treated With Antipsychotic Drugs—Linking Magnetic Resonance Imaging Findings to Cellular Pathology

(2013) Anthony C. Vernon et al.   BIOLOGICAL PSYCHIATRY

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

(2013) Helena W Morrison et al.   Journal of Neuroinflammation

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

(2013) Donal T. Skelly et al.   PLoS One

Pretreatment of aripiprazole and minocycline, but not haloperidol, suppresses oligodendrocyte damage from interferon-γ-stimulated microglia in co-culture model

(2013) Yoshihiro Seki et al.   SCHIZOPHRENIA RESEARCH

Meta-Analysis of Lymphocytes in Schizophrenia: Clinical Status and Antipsychotic Effects

(2012) Brian J. Miller et al.   BIOLOGICAL PSYCHIATRY

A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation

(2012) William C Kreisl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4

(2012) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

An image analysis toolbox for high-throughput C. elegans assays

(2012) Carolina Wählby et al.   NATURE METHODS

Exploration of Optimal Dosing Regimens of Haloperidol, a D2 Antagonist, via Modeling and Simulation Analysis in a D2 Receptor Occupancy Study

(2012) Hyeong-Seok Lim et al.   PHARMACEUTICAL RESEARCH

An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo

(2012) Cleopatra Kozlowski et al.   PLoS One

Meta-Analysis of Cytokine Alterations in Schizophrenia: Clinical Status and Antipsychotic Effects

(2011) Brian J. Miller et al.   BIOLOGICAL PSYCHIATRY

Effect of Chronic Antipsychotic Treatment on Brain Structure: A Serial Magnetic Resonance Imaging Study with Ex Vivo and Postmortem Confirmation

(2011) Anthony C. Vernon et al.   BIOLOGICAL PSYCHIATRY

11C-(R)-PK11195 PET Imaging of Microglial Activation and Response to Minocycline in Zymosan-Treated Rats

(2011) A. K. Converse et al.   JOURNAL OF NUCLEAR MEDICINE

Aripiprazole inhibits superoxide generation from phorbol-myristate-acetate (PMA)-stimulated microglia in vitro: Implication for antioxidative psychotropic actions via microglia

(2011) Takahiro A. Kato et al.   SCHIZOPHRENIA RESEARCH

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106

(2010) Akihiro Takano et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Acute D2 receptor blockade induces rapid, reversible remodeling in human cortical-striatal circuits

(2010) Heike Tost et al.   NATURE NEUROSCIENCE

DeadEasy Mito-Glia: Automatic Counting of Mitotic Cells and Glial Cells in Drosophila

(2010) Manuel Guillermo Forero et al.   PLoS One

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study

(2009) J. Doorduin et al.   JOURNAL OF NUCLEAR MEDICINE

Microglia Activation in Recent-Onset Schizophrenia: A Quantitative (R)-[11C]PK11195 Positron Emission Tomography Study

(2008) Bart N. van Berckel et al.   BIOLOGICAL PSYCHIATRY

Inhibitory effects of aripiprazole on interferon--induced microglial activation via intracellular Ca2+regulationin vitro

(2008) Takahiro Kato et al.   JOURNAL OF NEUROCHEMISTRY

The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-γ

(2007) Qian Bian et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH