Article
Polymer Science
Konrad Gziut, Agnieszka Kowalczyk, Beata Schmidt, Krzysztof Kowalczyk, Mateusz Weisbrodt
Summary: New modifiers for epoxy-resin-based self-adhesive tapes were prepared via FRBP, with different UV photoinitiators and mixing speeds affecting the copolymer content, viscosity, molecular weights, and polydispersity of the modifiers. These parameters in turn influenced the adhesion and shear strength of the self-adhesive tapes, with TPO-based modifiers showing better self-adhesive features but slightly lower shear strength compared to SAT-819. Factors such as polydispersity of acrylate copolymers and crosslinking degree also played a role in the mechanical strength of the cured tapes.
Article
Multidisciplinary Sciences
Joo Sung Kim, Jung-Min Heo, Gyeong-Su Park, Seung-Je Woo, Changsoon Cho, Hyung Joong Yun, Dong-Hyeok Kim, Jinwoo Park, Seung-Chul Lee, Sang-Hwan Park, Eojin Yoon, Neil C. Greenham, Tae-Woo Lee
Summary: This study reports the development of ultra-bright, efficient, and stable light-emitting diodes (PeLEDs) made of core/shell perovskite nanocrystals. The nanocrystals, obtained through in situ reaction of benzylphosphonic acid with polycrystalline perovskite films, demonstrate strong carrier confinement and maintain good charge-transport properties.
Article
Dentistry, Oral Surgery & Medicine
Ima Y. Rad, Steven Lewis, Matthew D. Barros, Matt Kipper, Jeffrey W. Stansbury
Summary: This study demonstrates a method to increase the lifespan of dental restorative polymers in water by adding styrenic nanogels to maintain their mechanical properties and reduce hydrolytic degradation. High loading levels of styrenic nanogels can improve the polymer's water resistance, providing an excellent alternative to eliminate the adverse effects of water and saliva fluids.
Article
Polymer Science
Benjamin Gyarmati, Aysel Mammadova, Dora Barczikai, Gergely Stankovits, Anil Misra, Mohammad S. Alavijeh, Zoltan Varga, Krisztina Laszlo, Andras Szilagyi
Summary: This study investigated the controlled degradation of cysteamine-modified polyaspartamides with different side groups at different pH conditions, showing that the presence of DME side groups can induce degradation of the polymers. The degradation rate and stability of the polyaspartamides could be adjusted by varying the DME, DMP, and HE content. The results suggest that the degradation primarily involves main-chain degradation in the presence of DME groups.
POLYMER DEGRADATION AND STABILITY
(2021)
Article
Engineering, Biomedical
Jose Abraham Gonzalez-Lopez, Abril Fonseca-Garcia, Ricardo Acosta-Ortiz, Rebeca Betancourt-Galindo, Erick Martinez-Ruiz, Maria Esther Trevino-Martinez
Summary: This study synthesized a monomer MVTPM and evaluated its performance in composite resin formulations. The experimental results showed that the MVTPM monomer has potential applications in dental composite resin formulations and can improve the hydrolytic behavior, hygroscopic behavior, and shrinkage stress of the resin.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Chemistry, Physical
Carlos Enrique Cuevas-Suarez, Eliseu Aldrighi Munchow, Christian Goncalves Schwarzbold, Josiane Kuhn Rutz, Adriana Fernandes da Silva, Evandro Piva
Summary: This study evaluated the properties of adhesive resins modified with different antioxidants as polymerization inhibitors. The results showed that adhesives modified with BHT and AA had lower degree of conversion, while the presence of QC resulted in color changes and higher yellowing index. The addition of GA reduced the cohesive strength of the materials. However, all adhesives demonstrated similar cell viability and translucency compared to the control. The use of alternative antioxidants showed potential for the development of dental adhesive resins without significant impairment of their properties.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Polymer Science
Iris Lamparth, David Wottawa, Jorg Angermann, Pascal Fassler, Robert Liska, Yohann Catel
Summary: This study investigated the effects of four new urethane-based AFCT agents on dental composites, which can improve mechanical properties and reduce shrinkage force, providing effective technological support for the formulation of low-shrinkage materials.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Polymer Science
Alma Antonia Perez-Mondragon, Carlos Enrique Cuevas-Suarez, Jesus Garcia-Serrano, Nayely Trejo-Carbajal, A. Lobo-Guerrero, Ana M. Herrera-Gonzalez
Summary: By replacing EDAB with TTME or TTAC monomers, the experimental adhesive systems achieved high double bond conversion and low polymerization rate, resulting in high shelf-life stability. The physical properties and bond strength of the experimental adhesive resins were similar to the control adhesive resins.
Article
Engineering, Chemical
Soilikki Kotanen, Minna Poikelispaa, Alexander Efimov, Tapani Harjunalanen, Christopher Mills, Timo Laaksonen, Essi Sarlin
Summary: Polyurethane/polyhydroxyurethane (PU/PHU) hybrid materials show potential as alternatives to PU adhesives with good mechanical and adhesive properties, but are susceptible to water uptake leading to potential bond failure. After water immersion, cohesive strength of PU/PHU increases while adhesive strength decreases, requiring careful application design for optimal usage.
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
(2021)
Article
Dentistry, Oral Surgery & Medicine
R. Alkattan, G. Koller, S. Banerji, S. Deb
Summary: This study evaluated the etching effect, interfacial characteristics, and enzyme inhibition of dental hard tissue by bis[2-(methacryloyloxy) ethyl] phosphate (BMEP) primers, compared to a 10-methacryloyloxydecyl dihydrogen phosphate (10-MDP) system. Results showed that BMEP primers exhibited stronger etching, longer resin tags, better polymerization, and higher inhibition of matrix metalloproteinase (MMP) enzymes compared to the 10-MDP-based system.
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Polymer Science
Benjamin Grob, Benedikt Frieser, Robert Liska, Yohann Catel
Summary: Polymerization shrinkage and shrinkage stress are crucial issues in dental restorations. Addition fragmentation chain transfer agents (AFCT agents) are effective in reducing shrinkage stress. Four novel polymerizable allyl sulfides were synthesized and evaluated in dental composites. AFCT-based composites showed good performance.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Arwa Almusa, Antonio H. S. Delgado, Paul Ashley, Anne M. Young
Summary: The aim of this study was to develop a rapid method for determining the chemical composition, solvent evaporation rates, and polymerization kinetics of dental adhesives. Different adhesives showed significant differences in filler content, monomers, solvents, and polymerization extent, which is important for understanding their properties.
Article
Biochemistry & Molecular Biology
Rauno Sedrik, Olivier Bonjour, Siim Laanesoo, Ilme Liblikas, Tonis Pehk, Patric Jannasch, Lauri Vares
Summary: Incorporating rigid cyclic acetal and ketal units into polymer structures is important for developing recyclable high-performance materials from renewable resources. In this study, citric acid was converted into di- and tricyclic diketones, which were then used to synthesize rigid spirodiols through ketalization. The resulting poly(beta-thioether ester ketal)s exhibited thermal stability and potential for chemical recycling.
Article
Chemistry, Physical
Nachnicha Kongkatigumjorn, Pichapak Srikamut, Farzad Seidi, Sareeya Bureekaew, Daniel Crespy
Summary: Controlling the hydrolysis rate of polymer conjugates is crucial for the precise delivery of active molecules. By inserting substituent groups, the hydrolysis rate and selectivity of thioether ester groups can be tuned. This design is used to prepare metal coatings with excellent anticorrosion performance.
CHEMISTRY OF MATERIALS
(2022)
Review
Polymer Science
Vincent S. D. Voet, Jarno Guit, Katja Loos
Summary: The global market for 3D printing materials has grown rapidly in the past decade, with photopolymers dominating sales. However, the lack of sustainable resins that can compete with commercial materials in vat photopolymerization remains a challenge. Developing green alternatives is crucial for reducing the environmental impact of additive manufacturing.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Article
Chemistry, Applied
Laura Marcela Forero Ramirez, Elise Gobin, Rachida Aid-Launais, Clement Journe, Fernanda C. Moraes, Luc Picton, Didier Le Cerf, Didier Letourneur, Cedric Chauvierre, Frederic Chaubet
CARBOHYDRATE POLYMERS
(2020)
Article
Pharmacology & Pharmacy
Jingwen Qiu, Xue Li, Karine Steenkeste, Nadine Barroca-Aubry, Caroline Aymes-Chodur, Philippe Roger, Juan M. Casas-Solvas, Antonio Vargas-Berenguel, Christophe Rihouey, Luc Picton, Ruxandra Gref
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2020)
Article
Chemistry, Applied
Ahdi Hadrich, Virginie Dulong, Christophe Rihouey, Beatrice Labat, Luc Picton, Didier Le Cerf
CARBOHYDRATE POLYMERS
(2020)
Article
Chemistry, Medicinal
Nesrine Gargouch, Fatma Elleuch, Ines Karkouch, Olfa Tabbene, Chantal Pichon, Christine Gardarin, Christophe Rihouey, Luc Picton, Slim Abdelkafi, Imen Fendri, Celine Laroche
Summary: Marine microalgae-derived exopolysaccharides (EPS) show promising biological activities, including antibacterial, anti-fungal, and anti-Candida albicans properties. EPS produced by Porphyridium marinum and its oligomers exhibit high efficiency in inhibiting bacterial growth, reducing biofilm formation, and affecting the viability of breast cancer cells.
Article
Materials Science, Ceramics
Jeremy Marie, Julie Bourret, Pierre-Marie Geffroy, Thierry Chartier, Marguerite Bienia, Vincent Chaleix, Luc Picton, Agnes Smith
Summary: This work focuses on the preparation of concentrated alumina suspensions using bio-sourced additives with low environmental impact, investigating their rheological properties and their effect on tape casting. Natural polysaccharides extracted from plants and fruits were identified as promising binders and their rheological behavior was studied, along with the mechanical properties of the resulting green tapes. The research explores the relationships between binder nature, suspension rheology, tape casting capabilities, and final properties of the green and sintered tapes.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2021)
Article
Biochemical Research Methods
Laura Marcela Forero Ramirez, Christophe Rihouey, Frederic Chaubet, Didier Le Cerf, Luc Picton
Summary: Accurate determination of particle size and PSD is crucial for clinical translation of medical nanoparticles. In this study, dextran-based NPs were characterized using traditional techniques and FI-AF4, showing FI-AF4 is a powerful method for characterizing dextran-NPs. It provided a more realistic and comprehensive picture of PSD compared to batch-mode light scattering techniques.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Biochemistry & Molecular Biology
Virginie Dulong, Morgane Morel, Beatrice Labat, Luc Picton, Didier Le Cerf
Summary: The size of microgels is influenced by the laccase activity and dispersion time. The hydrophobic microdomains formed by ferulic acid moieties play a key role in the encapsulation of curcumin, while lidocaine release rate depends on the type of buffer solution.
MACROMOLECULAR BIOSCIENCE
(2021)
Article
Polymer Science
Mathieu Madau, Gaelle Morandi, Christophe Rihouey, Vincent Lapinte, Hassan Oulyadi, Didier LE Cerf, Virginie Dulong, Luc Picton
Summary: Hyaluronic acid of different molar masses was used as terminating agents in the cationic ring-opening polymerization of 2-methyl-2-oxazoline, resulting in HA-g-PMeOx copolymers with varying degrees of substitution. These copolymers showed thermally dependent hydrogel properties in aqueous solutions, making them potentially valuable for biomedical applications.
Article
Chemistry, Physical
Huu Van Le, Virginie Dulong, Luc Picton, Didier Le Cerf
Summary: Polyelectrolyte complexes (PECs) of hyaluronic acid (HA) and diethylaminoethyl dextran (DEAE-D) for biomedical applications exhibit specific physicochemical properties related to particle size, hydrophobicity, and storage stability. Factors such as charge ratio, polymer concentration, molar masses of HA, ionic strength, and mixing methods have been found to influence the properties of these complexes, shedding light on their potential use for encapsulating hydrophobic active molecules for drug delivery purposes.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Pharmacology & Pharmacy
Jingwen Qiu, Xue Li, Mahsa Rezaei, Gilles Patriarche, Juan M. Casas-Solvas, Borja Moreira-Alvarez, Jose Manuel Costa Fernandez, Jorge R. Encinar, Farah Savina, Luc Picton, Antonio Vargas-Berenguel, Ruxandra Gref
Summary: By coating highly porous nanoscale metal-organic frameworks (nanoMOFs) with cyclodextrin (CD)-based oligomers, a biodegradable shell was successfully engineered to encapsulate the anticancer drug doxorubicin (DOX) with high loading efficiencies. The drug release behavior of the core-shell nanoMOFs exhibited pH-dependent characteristics, with significantly lower release at pH 7.4 compared to pH 4.5, showing potential for controlled drug delivery applications.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Polymer Science
Mathieu Madau, Gaelle Morandi, Vincent Lapinte, Didier Le Cerf, Virginie Dulong, Luc Picton
Summary: HA-based thermo-responsive hydrogels were obtained through functionalization with PiPrOx-co-PnBuOx copolymers. The hydrogel transition temperature can be controlled by varying the monomeric composition.
Article
Chemistry, Applied
Huu Van Le, Virginie Dulong, Luc Picton, Didier Le Cerf
Summary: A novel kind of thermoresponsive polyelectrolyte complex-based nanogels (PEC-NGs) were developed by mixing hyaluronic acid functionalized with Jeffamine M-2005 and either DEAE-D or PLL. The presence of M2005 grafts led to PEC-NGs with larger particle size, lower net surface charge, and thermoresponsiveness. Replacing DEAE-D with PLL improved stability against salinity and encapsulation of curcumin.
CARBOHYDRATE POLYMERS
(2022)
Article
Biochemistry & Molecular Biology
Mengli Ding, Jingwen Qiu, Stephan Rouziere, Christophe Rihouey, Luc Picton, Ruxandra Gref
Summary: Due to their flexible composition, large surface areas, versatile surface properties, and degradability, nanoscale metal organic frameworks (nano MOFs) are drawing significant attention in nanomedicine. In particular, iron trimesate MIL-100 (Fe) is extensively studied in drug delivery. The challenging synthesis of room-temperature (RT) MIL100 has been addressed by using acetic acid as a modulator and non-toxic cyclodextrin-based coatings for stability. RT MIL100 obtained using acetic acid showed good colloidal stability, low cytotoxicity, and high drug payload efficiency, making it suitable for cancer therapy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Huu Van Le, Virginie Dulong, Luc Picton, Didier Le Cerf
Summary: The lyophilization of nanogels allows for long-term conservation and adjustment of their concentration and dispersant type. This study investigated the effects of formulation aspects on the integrity of polyelectrolyte complex nanogels after lyophilization and reconstitution. The best approach for freeze-drying thermoresponsive PEC-NGs was determined, and it was found that freeze-drying PEC-NG suspensions prepared at a relatively low polymer concentration with trehalose as a cryoprotectant allowed for homogeneous redispersion of PEC-NGs without significant aggregation.
Article
Polymer Science
Mathieu Madau, Didier Le Cerf, Virginie Dulong, Luc Picton
Summary: Two routes were investigated to functionalize hyaluronic acid (HA) of different molar masses with poly(etheramine) M2005, leading to the formation of physical thermo-responsive hydrogels. The use of either water or N,N'-Dimethylformamide (DMF) in the coupling reactions resulted in different grafting degrees of M2005, with the DMF route showing better thermo-responsive properties of the hydrogels.