Porous nanoparticles with engineered shells release their drug cargo in cancer cells

Doxorubicin-Loaded Metal-Organic Frameworks Nanoparticles with Engineered Cyclodextrin Coatings: Insights on Drug Location by Solid State NMR Spectroscopy

(2021) Xue Li et al.   Nanomaterials

Doxorubicin Loading Capacity of MIL-100(Fe): Effect of Synthesis Conditions

(2020) Abhik Bhattacharjee et al.   Journal of Inorganic and Organometallic Polymers and Materials

Cryopreservation of Human iPS Cell Aggregates in a DMSO-Free Solution—An Optimization and Comparative Study

(2020) Rui Li et al.   Frontiers in Bioengineering and Biotechnology

Self-assembled multifunctional core–shell highly porous metal–organic framework nanoparticles

(2020) Jingwen Qiu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Application of MIL-100(Fe) in drug delivery and biomedicine

(2020) Christian Rafael Quijia et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections

(2019) Xue Li et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Design of Engineered Cyclodextrin Derivatives for Spontaneous Coating of Highly Porous Metal-Organic Framework Nanoparticles in Aqueous Media

(2019) Cutrone et al.   Nanomaterials

Comb-like dextran copolymers: A versatile strategy to coat highly porous MOF nanoparticles with a PEG shell

(2019) Giovanna Cutrone et al.   CARBOHYDRATE POLYMERS

Highly Porous Hybrid Metal–Organic Nanoparticles Loaded with Gemcitabine Monophosphate: a Multimodal Approach to Improve Chemo‐ and Radiotherapy

(2019) Xue Li et al.   ChemMedChem

Nanoparticles of Metal-Organic Frameworks: On the Road to In Vivo Efficacy in Biomedicine

(2018) Teresa Simon-Yarza et al.   ADVANCED MATERIALS

Facile Fabrication of Reduction-Responsive Supramolecular Nanoassemblies for Co-delivery of Doxorubicin and Sorafenib toward Hepatoma Cells

(2018) Qingqing Xiong et al.   Frontiers in Pharmacology

MIL-100(Al) Gels as an Excellent Platform Loaded with Doxorubicin Hydrochloride for pH-Triggered Drug Release and Anticancer Effect

(2018) Yuge Feng et al.   Nanomaterials

A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles

(2017) Jing Wang et al.   JOURNAL OF CONTROLLED RELEASE

NanoMIL-100(Fe) containing docetaxel for breast cancer therapy

(2017) Mahsa Rezaei et al.   Artificial Cells Nanomedicine and Biotechnology

PPy@MIL-100 Nanoparticles as a pH- and Near-IR-Irradiation-Responsive Drug Carrier for Simultaneous Photothermal Therapy and Chemotherapy of Cancer Cells

(2016) Yu-Da Zhu et al.   ACS Applied Materials & Interfaces

In vivo behavior of MIL-100 nanoparticles at early times after intravenous administration

(2016) T. Simon-Yarza et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Approaches to drug delivery: Confinement of aspirin in MIL-100(Fe) and aspirin in the de novo synthesis of metal–organic frameworks

(2016) Brenda Singco et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Antineoplastic busulfan encapsulated in a metal organic framework nanocarrier: first in vivo results

(2016) M. T. Simon-Yarza et al.   Journal of Materials Chemistry B

MOF nanoparticles coated by lipid bilayers and their uptake by cancer cells

(2015) Stefan Wuttke et al.   CHEMICAL COMMUNICATIONS

Efficient “green” encapsulation of a highly hydrophilic anticancer drug in metal–organic framework nanoparticles

(2015) Violeta Rodriguez-Ruiz et al.   JOURNAL OF DRUG TARGETING

A “green” strategy to construct non-covalent, stable and bioactive coatings on porous MOF nanoparticles

(2015) V. Agostoni et al.   Scientific Reports

Heparin-Engineered Mesoporous Iron Metal-Organic Framework Nanoparticles: Toward Stealth Drug Nanocarriers

(2015) Elena Bellido et al.   Advanced Healthcare Materials

Host–Guest Interactions in Fe(III)-Trimesate MOF Nanoparticles Loaded with Doxorubicin

(2014) Resmi Anand et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Aspects of determining the molecular weight of cyclodextrin polymers and oligomers by static light scattering

(2013) István Puskás et al.   CARBOHYDRATE POLYMERS

A “Ship in a Bottle” Strategy To Load a Hydrophilic Anticancer Drug in Porous Metal Organic Framework Nanoparticles: Efficient Encapsulation, Matrix Stabilization, and Photodelivery

(2013) Maria Rosaria di Nunzio et al.   JOURNAL OF MEDICINAL CHEMISTRY

pH-activated doxorubicin release from polyelectrolyte complex layer coated mesoporous silica nanoparticles

(2013) L. Minati et al.   MICROPOROUS AND MESOPOROUS MATERIALS

In depth analysis of the in vivo toxicity of nanoparticles of porous iron(iii) metal–organic frameworks

(2013) Tarek Baati et al.   Chemical Science

Towards an Improved anti-HIV Activity of NRTI via Metal-Organic Frameworks Nanoparticles

(2013) Valentina Agostoni et al.   Advanced Healthcare Materials

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Metal–Organic Frameworks in Biomedicine

(2011) Patricia Horcajada et al.   CHEMICAL REVIEWS

Porous metal organic framework nanoparticles to address the challenges related to busulfan encapsulation

(2011) T Chalati et al.   Nanomedicine

Intracellular pH-Responsive Mesoporous Silica Nanoparticles for the Controlled Release of Anticancer Chemotherapeutics

(2010) Chia-Hung Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polymer micelles with cross-linked polyanion core for delivery of a cationic drug doxorubicin

(2009) Jong Oh Kim et al.   JOURNAL OF CONTROLLED RELEASE

Doxorubicin conjugated gold nanoparticles as water-soluble and pH-responsive anticancer drug nanocarriers

(2009) Santosh Aryal et al.   JOURNAL OF MATERIALS CHEMISTRY

Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

(2009) Patricia Horcajada et al.   NATURE MATERIALS