Article
Biochemistry & Molecular Biology
Natalia S. S. Guimaraes, Vyctoria S. Ramos, Laura F. L. Prado-Souza, Rayssa M. Lopes, Gabriel S. Arini, Luis G. P. Feitosa, Ricardo R. Silva, Iseli L. Nantes, Debora C. Damasceno, Norberto P. Lopes, Tiago Rodrigues
Summary: The study found that rosemary is an aromatic herb with antimicrobial and antioxidant activities, which can be used as a condiment and in folk medicine. The study also found that a rosemary extract can protect liver mitochondria from oxidative damage in vitro and have antioxidant and hepatoprotective effects in vivo. These findings highlight the potent antioxidant activity of rosemary and its potential health benefits.
Article
Plant Sciences
Matteo Politi, Claudio Ferrante, Luigi Menghini, Paola Angelini, Giancarlo Angeles Flores, Beatrice Muscatello, Alessandra Braca, Marinella De Leo
Summary: This study evaluated the aromatic waters of rosemary, sage, and cypress and found that they have antimycotic and cytotoxic effects. The exhaustive analysis techniques used in this study provided valuable insights into the metabolite fingerprint differences of these commercial products. The results suggest that these hydrosols could be a significant source of phytochemicals with pharmacological potential.
Article
Plant Sciences
Ana Paula Martin, Maria Florencia Martinez, Maria Amalia Chiesa, Lucila Garcia, Nadia Gerhardt, Facundo Uviedo, Pablo S. Torres, Maria Rosa Marano
Summary: Plant bioactive compounds, such as rosemary-derived extracts, show potential in controlling plant diseases due to their antimicrobial and antioxidant activities. However, the effects of these extracts on plant diseases are not well understood, restricting their application in agriculture.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Lucas Malvezzi de Macedo, Erica Mendes dos Santos, Janaina Artem Ataide, Gabriela Trindade de Souza e Silva, Joao Paulo de Oliveira Guarnieri, Marcelo Lancellotti, Angela Faustino Jozala, Paulo Cesar Pires Rosa, Priscila Gava Mazzola
Summary: This study aimed to develop a topical formulation with rosemary extract that had antimicrobial and antioxidant activity. Different extraction methods were evaluated, and the infusion and Soxhlet methods showed promising results. The developed formulation containing the infusion extract showed stable characteristics and high levels of acceptance among volunteers, suggesting its potential use as a phytocosmetic. This study also reports the first attempt to produce an oil-in-water emulsion using only natural excipients and rosemary extract, which is a promising novelty.
Article
Biochemistry & Molecular Biology
Irina Ielciu, Mihaela Niculae, Emoke Pall, Cristina Barbalata, Ioan Tomuta, Neli-Kinga Olah, Ramona Flavia Burtescu, Daniela Benedec, Ilioara Oniga, Daniela Hanganu
Summary: This study evaluated the effects of R. officinalis-loaded liposomes on cell proliferation and antimicrobial activity. The liposomes showed high encapsulation efficiency, stability, and selective toxicity towards cancer cells, as well as effective antimicrobial activity against Gram-positive bacteria. These findings confirm the biological activities of R. officinalis and propose novel delivery systems for enhanced polyphenol activity.
Review
Biochemistry & Molecular Biology
Federica Li Pomi, Vincenzo Papa, Francesco Borgia, Mario Vaccaro, Alessandro Allegra, Nicola Cicero, Sebastiano Gangemi
Summary: Rosemary and its bioactive compounds have antioxidant properties and exhibit anti-inflammatory, antimicrobial, wound-healing, and anticancer activity in dermatological practice. However, large and controlled clinical trials are needed to definitively determine the real impact of rosemary and its components in clinical practice.
Article
Biochemistry & Molecular Biology
Rosaria Francolino, Mara Martino, Lucia Caputo, Giuseppe Amato, Giuseppina Chianese, Ernesto Gargiulo, Carmen Formisano, Benedetta Romano, Giuseppe Ercolano, Angela Ianaro, Laura De Martino, Vincenzo De Feo
Summary: This study compared the chemical profile and bioactivities of hydroalcoholic extracts from wild and cultivated Rosmarinus officinalis. The extracts showed similar antioxidant activity and inhibition of enzyme activities. Additionally, the extracts exhibited anti-inflammatory and antioxidant effects through modulation of the nitric oxide pathway and inhibition of NF-kB and COX-2. These findings suggest that R. officinalis extracts could be developed as novel therapeutic strategies for inflammation-based diseases, as well as for food and pharmaceutical purposes.
Article
Chemistry, Applied
Engy M. Saad, Nesrine Abdelrehim El Gohary, Mohammad Abdel-Halim, Heba Handoussa, Rasha Mohamed El Nashar, Boris Mizaikoff
Summary: This study demonstrates a robust and reproducible approach for selectively extracting rosmarinic acid using molecularly imprinted polymers. By optimizing the molecularly imprinted solid phase extraction protocol, a remarkably selective extraction of RA from real-world Rosmarinus officinalis L. extract was achieved, with a recovery rate and purity of 81.96 +/- 6.33% and 80.59 +/- 0.30%, respectively.
Article
Integrative & Complementary Medicine
Zhong Xiang-Jian, Zhou Na, Wang Xin, Li Jin-Jie, Ma Hui, Mao Yue, Xu Jia-Hui, Lin Peng-Cheng, Shang Xiao-Ya
Summary: Three new ursane-type triterpenoids were isolated from the ethanolic extract of Rosmarinus officinalis, and their structures were determined by NMR experiments. These compounds showed significant inhibitory effects on nitric oxide production in lipopolysaccharide-activated mouse RAW264.7 macrophages, but no antibacterial activity was observed at a concentration of 128 μg/mL.
CHINESE JOURNAL OF NATURAL MEDICINES
(2022)
Article
Biotechnology & Applied Microbiology
Raya Algonaiman, Hend F. Alharbi, Hassan Barakat
Summary: This study aimed to examine the antidiabetic and hypolipidemic potential activities of L. plantarum fermented oat extract in Streptozotocin-induced diabetic rats. The fermented oat extract alleviated hyperglycemia and improved serum lipid profiles in the diabetic rats, while also promoting hepatoprotective and nephroprotective characteristics.
FERMENTATION-BASEL
(2022)
Article
Biochemistry & Molecular Biology
Eleni Kakouri, Olti Nikola, Charalabos Kanakis, Kyriaki Hatziagapiou, George Lambrou, Panayiotis Trigas, Christina Kanaka-Gantenbein, Petros A. Tarantilis
Summary: The hydroethanolic extract of Rosmarinus officinalis exhibits cytotoxic activity against glioblastoma and rhabdomyosarcoma cell lines, with high phenolic content and antioxidant activity.
Article
Nutrition & Dietetics
Nadiah S. Alzahrani, Ghedeir M. Alshammari, Afaf El-Ansary, Abu ElGasim A. Yagoub, Musarat Amina, Ali Saleh, Mohammed Abdo Yahya
Summary: This study found that whole pearl millet grain powder and its ethanol extract have anti-hyperlipidemic, hypoglycemic, hepatoprotective, and anti-inflammatory effects. The study used obese rats fed a high-fat diet and divided them into different treatment groups, administering varying doses of MPG powder or MPGethaolE, and observed changes in different indicators.
Article
Chemistry, Applied
Xiangjian Zhong, Xin Wang, Na Zhou, Jinjie Li, Jiachen Liu, Jianyu Yue, Xiaomeng Hao, Maoluo Gan, Pengcheng Lin, Xiaoya Shang
Summary: The polar fraction of rosemary exhibited stronger antibacterial activity than its essential oil, making it a promising potential as a food additive.
Article
Chemistry, Medicinal
Na Zhou, Ze-yu Wang, Yong Wu, Xiang-jian Zhong, Xin Wang, Jin-jie Li, Xiao-ya Shang
Summary: Five norursane-type triterpenoids, including three novel compounds, were isolated from the ethanol extract of Rosmarinus officinalis. These compounds showed significant inhibitory effects on NO production in LPS-activated cells, with compounds 2, 3, and 5 exhibiting better anti-inflammatory activity.
Review
Agriculture, Dairy & Animal Science
Radhia Aitfella Lahlou, Mustapha Bounechada, Arezki Mohammedi, Luis R. Silva, Gilberto Alves
Summary: Coccidiosis is a parasitic disease caused by protozoa which affects poultry production significantly. Anticoccidial drugs and vaccination are common preventive measures, but drug resistance and environmental pollutants have led to a search for alternative methods. The use of medicinal plants or plant-derived products could provide a solution, as they contain bioactive compounds that could be developed into new chemical entities.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Biology
Enas Nabil Danial, Najla Osman Aly Ayaz, Hanan Saeed Omer Alnahdi
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2015)
Article
Biology
Enas N. Danial, Amal H. Hamza, Rasha H. Mahmoud
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
(2015)
Article
Pharmacology & Pharmacy
Suzan Khayyat, Manal Al-Kattan, Nour Basudan
INTERNATIONAL JOURNAL OF PHARMACOLOGY
(2018)
Article
Biology
Ghada E. A. Awad, Mohamed M. I. Helal, Enas N. Danial, Mona A. Esawy
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2014)
Article
Food Science & Technology
Enas N. Danial, Majd Y. Lamfon, Leen A. Alghamdi, Amna M. Alamri, Malak S. Alghamdi, Soha A. Alghamdi
Summary: The study investigated the ability of ten lactic acid bacteria species to eliminate or inhibit Aflatoxin G(1) (AFG(1)), a hepatocarcinogenic mycotoxin, from media, and found that the efficiency varied depending on the strain and media type. Cold storage was found to be more effective in reducing AFG(1) content compared to higher temperatures for certain LAB strains.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Article
Biotechnology & Applied Microbiology
Manal O. Alkattan, Enas N. Danial, Wafa A. Alshehri, Fathia El Halawany, Njood A. Alzumay
Summary: Many infectious diseases can be treated using herbal medicines, which play a major role in therapeutic medicine and are widely used in developing countries. This study evaluated the potential of Avicennia marina and Suaeda monoica leaf extracts as antidermatophytic agents.
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Manal Al-Kattan, Enas N. Danial, Njood Al-Zumay
INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH
(2019)
Article
Engineering, Biomedical
Suzan Khayyat, Manal Othman Al-Kattan
BIOMEDICAL RESEARCH-INDIA
(2017)
Article
Engineering, Biomedical
Manal Othman Al-Kattan, Suzan A. Khayyat
BIOMEDICAL RESEARCH-INDIA
(2017)
Article
Biology
Kholoud S. Ramadan, Salha A. Alshamrani
Article
Biotechnology & Applied Microbiology
Enas N. Danial, Nayera A. M. Abdelwahed
RESEARCH JOURNAL OF BIOTECHNOLOGY
(2015)
Article
Chemistry, Multidisciplinary
Amna A. Saddiq, Enas N. Danial
MAIN GROUP CHEMISTRY
(2014)
Article
Biotechnology & Applied Microbiology
Amal H. Hamza, Widad Al-Bishri, H. H. Omar, Enas N. Danial
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2014)
Article
Biotechnology & Applied Microbiology
Enas N. Danial, Jehad M. Yousef
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2014)