Properties and biotechnological applications of natural and engineered haloalkane dehalogenases

A selection assay for haloalkane dehalogenase activity based on toxic substrates

(2015) Michael P. C. Fibinger et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Valence Bond and Enzyme Catalysis: A Time To Break Down and a Time To Build Up

(2015) Avital Sharir-Ivry et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Pseudomonas putida Strain Genetically Engineered for 1,2,3-Trichloropropane Bioremediation

(2014) Ghufrana Samin et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism

(2014) Lijun Guan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Computational Library Design for Increasing Haloalkane Dehalogenase Stability

(2014) Robert J. Floor et al.   CHEMBIOCHEM

Immobilized Synthetic Pathway for Biodegradation of Toxic Recalcitrant Pollutant 1,2,3-Trichloropropane

(2014) Pavel Dvorak et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Biochemical and structural characterisation of a haloalkane dehalogenase from a marineRhodobacteraceae

(2014) Halina R. Novak et al.   FEBS LETTERS

Mechanism-Based Discovery of Novel Substrates of Haloalkane Dehalogenases Using in Silico Screening

(2014) Lukas Daniel et al.   Journal of Chemical Information and Modeling

Computationally Efficient and Accurate Enantioselectivity Modeling by Clusters of Molecular Dynamics Simulations

(2014) Hein J. Wijma et al.   Journal of Chemical Information and Modeling

Dynamics and hydration explain failed functional transformation in dehalogenase design

(2014) Jan Sykora et al.   Nature Chemical Biology

Cloning, expression, purification and three-dimensional structure prediction of haloalkane dehalogenase from a recently isolated Ancylobacter aquaticus strain UV5

(2014) Ajit Kumar et al.   PROTEIN EXPRESSION AND PURIFICATION

Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites

(2014) Radka Chaloupkova et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystallographic analysis of 1,2,3-trichloropropane biodegradation by the haloalkane dehalogenase DhaA31

(2014) Maryna Lahoda et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Stepwise enhancement of catalytic performance of haloalkane dehalogenase LinB towards β-hexachlorocyclohexane

(2014) Ryota Moriuchi et al.   AMB Express

Crystallographic analysis of new psychrophilic haloalkane dehalogenases: DpcA fromPsychrobacter cryohalolentisK5 and DmxA fromMarinobactersp. ELB17

(2013) Katsiaryna Tratsiak et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel

(2013) Tana Koudelakova et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DspA from Strongylocentrotus purpuratus: The first biochemically characterized haloalkane dehalogenase of non-microbial origin

(2013) Andrea Fortova et al.   BIOCHIMIE

The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA fromAgrobacterium tumefaciensC58

(2013) Khomaini Hasan et al.   FEBS Journal

Crystal Structure and Site-Directed Mutagenesis Analyses of Haloalkane Dehalogenase LinB from Sphingobium sp. Strain MI1205

(2013) M. Okai et al.   JOURNAL OF BACTERIOLOGY

Release of Halide Ions from the Buried Active Site of the Haloalkane Dehalogenase LinB Revealed by Stopped-Flow Fluorescence Analysis and Free Energy Calculations

(2013) Jana Hladilkova et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Inverting hydrolases and their use in enantioconvergent biotransformations

(2013) Markus Schober et al.   TRENDS IN BIOTECHNOLOGY

Computer-Assisted Engineering of the Synthetic Pathway for Biodegradation of a Toxic Persistent Pollutant

(2013) Nagendra Prasad Kurumbang et al.   ACS Synthetic Biology

Biochemical Characterization of a Novel Haloalkane Dehalogenase from a Cold-Adapted Bacterium

(2012) Ivana Drienovska et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Haloalkane dehalogenases: Biotechnological applications

(2012) Tana Koudelakova et al.   Biotechnology Journal

Stereochemistry of LinB-catalyzed biotransformation of δ-HBCD to 1R,2R,5S,6R,9R,10S-pentabromocyclododecanol

(2012) Norbert V. Heeb et al.   CHEMOSPHERE

Biotransformation of Hexabromocyclododecanes (HBCDs) with LinB—An HCH-Converting Bacterial Enzyme

(2012) Norbert V. Heeb et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Enzymatic Conversion of ε-Hexachlorocyclohexane and a Heptachlorocyclohexane Isomer, Two Neglected Components of Technical Hexachlorocyclohexane

(2012) Kiran Bala et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cloning, functional expression, biochemical characterization, and structural analysis of a haloalkane dehalogenase from Plesiocystis pacifica SIR-1

(2011) Martin Hesseler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Substrate specificity of haloalkane dehalogenases

(2011) Tana Koudelakova et al.   BIOCHEMICAL JOURNAL

Directed Evolution Strategies for Enantiocomplementary Haloalkane Dehalogenases: From Chemical Waste to Enantiopure Building Blocks

(2011) Jan G. E. van Leeuwen et al.   CHEMBIOCHEM

Stereoselectivity and conformational stability of haloalkane dehalogenase DbjA from Bradyrhizobium japonicum USDA110: the effect of pH and temperature

(2011) Radka Chaloupkova et al.   FEBS Journal

Sequence diversity in haloalkane dehalogenases, as revealed by PCR using family-specific primers

(2011) Michael Kotik et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Marine Biocatalysts: Enzymatic Features and Applications

(2011) Antonio Trincone   Marine Drugs

Structure and activity of DmmA, a marine haloalkane dehalogenase

(2011) Jennifer J. Gehret et al.   PROTEIN SCIENCE

Dynamic Kinetic Resolution Process Employing Haloalkane Dehalogenase

(2011) Alja Westerbeek et al.   ACS Catalysis

Development of an enzymatic fiber-optic biosensor for detection of halogenated hydrocarbons

(2010) Sarka Bidmanova et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering

(2010) Zbynek Prokop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biochemical Characteristics of the Novel Haloalkane Dehalogenase DatA, Isolated from the Plant PathogenAgrobacterium tumefaciensC58

(2010) Khomaini Hasan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biochemistry of Microbial Degradation of Hexachlorocyclohexane and Prospects for Bioremediation

(2010) R. Lal et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Biochemical Characterization of Haloalkane Dehalogenases DrbA and DmbC, Representatives of a Novel Subfamily

(2009) A. Jesenska et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phytoremediation of small organic contaminants using transgenic plants

(2009) C Andrew James et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biohalogenation: Nature’s Way to Synthesize Halogenated Metabolites†

(2009) Claudia Wagner et al.   JOURNAL OF NATURAL PRODUCTS

Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate

(2009) Martina Pavlova et al.   Nature Chemical Biology

HaloTag7: A genetically engineered tag that enhances bacterial expression of soluble proteins and improves protein purification

(2009) Rachel Friedman Ohana et al.   PROTEIN EXPRESSION AND PURIFICATION

Sequence- and activity-based screening of microbial genomes for novel dehalogenases

(2009) Wing Yiu Chan et al.   Microbial Biotechnology

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Bacterial hydrolytic dehalogenases and related enzymes: Occurrences, reaction mechanisms, and applications

(2008) Tatsuo Kurihara et al.   CHEMICAL RECORD

Engineering a Catabolic Pathway in Plants for the Degradation of 1,2-Dichloroethane

(2008) G. L. Mena-Benitez et al.   PLANT PHYSIOLOGY

X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579

(2007) Pooja A. Mazumdar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS