Viral kinetic modeling: state of the art

Analysis of the hepatitis C viral kinetics during administration of two nucleotide analogues: sofosbuvir (GS-7977) and GS-0938

(2014) Jeremie Guedj et al.   ANTIVIRAL THERAPY

Effects of Aging on Influenza Virus Infection Dynamics

(2014) E. A. Hernandez-Vargas et al.   JOURNAL OF VIROLOGY

Impact of Different Oseltamivir Regimens on Treating Influenza A Virus Infection and Resistance Emergence: Insights from a Modelling Study

(2014) Laetitia Canini et al.   PLoS Computational Biology

Use of Laser Capture Microdissection to Map Hepatitis C Virus–Positive Hepatocytes in Human Liver

(2013) Abraham J. Kandathil et al.   GASTROENTEROLOGY

Modeling viral kinetics and treatment outcome during alisporivir interferon-free treatment in hepatitis C virus genotype 2 and 3 patients

(2013) Jeremie Guedj et al.   HEPATOLOGY

Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver

(2013) Stefan Wieland et al.   HEPATOLOGY

Towards multiscale modeling of influenza infection

(2013) Lisa N. Murillo et al.   JOURNAL OF THEORETICAL BIOLOGY

Modeling the Acute and Chronic Phases of Theiler Murine Encephalomyelitis Virus Infection

(2013) J. Zhang et al.   JOURNAL OF VIROLOGY

Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents

(2013) Libin Rong et al.   MATHEMATICAL BIOSCIENCES

Rapid host immune response and viral dynamics in herpes simplex virus-2 infection

(2013) Joshua T Schiffer et al.   NATURE MEDICINE

Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life

(2013) J. Guedj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity

(2013) Christine A. Jansen et al.   Scientific Reports

Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model

(2013) Libin Rong et al.   PLoS Computational Biology

Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals

(2013) Frank S. Heldt et al.   PLoS Computational Biology

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

(2013) Amber M. Smith et al.   PLoS Pathogens

Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract

(2013) Joshua T Schiffer et al.   eLife

Modeling Quasispecies and Drug Resistance in Hepatitis C Patients Treated with a Protease Inhibitor

(2012) Libin Rong et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Differential decay kinetics of human cytomegalovirus glycoprotein B genotypes following antiviral chemotherapy

(2012) Vincent C. Emery et al.   JOURNAL OF CLINICAL VIROLOGY

Understanding silibinin’s modes of action against HCV using viral kinetic modeling

(2012) Jeremie Guedj et al.   JOURNAL OF HEPATOLOGY

Combination Antiviral Therapy for Influenza: Predictions From Modeling of Human Infections

(2012) Alan S. Perelson et al.   JOURNAL OF INFECTIOUS DISEASES

Global Transcriptome Analysis in Influenza-Infected Mouse Lungs Reveals the Kinetics of Innate and Adaptive Host Immune Responses

(2012) Claudia Pommerenke et al.   PLoS One

Modeling Within-Host Dynamics of Influenza Virus Infection Including Immune Responses

(2012) Kasia A. Pawelek et al.   PLoS Computational Biology

A Viral Dynamic Model for Treatment Regimens with Direct-acting Antivirals for Chronic Hepatitis C Infection

(2012) Bambang S. Adiwijaya et al.   PLoS Computational Biology

Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

(2012) Ruy M. Ribeiro et al.   PLoS Pathogens

Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: Implications for treatment duration

(2011) Jeremie Guedj et al.   HEPATOLOGY

Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)

(2011) Jeremie Guedj et al.   HEPATOLOGY

IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C

(2011) P.-Y. Bochud et al.   JOURNAL OF HEPATOLOGY

The Kinetics of Mucosal Herpes Simplex Virus–2 Infection in Humans: Evidence for Rapid Viral-Host Interactions

(2011) Joshua T. Schiffer et al.   JOURNAL OF INFECTIOUS DISEASES

The impact of fibrosis and steatosis on early viral kinetics in HCV genotype 1-infected patients treated with Peg-IFN-alfa-2a and ribavirin

(2011) H. Guedj et al.   JOURNAL OF VIRAL HEPATITIS

Response Prediction in Chronic Hepatitis C by Assessment of IP-10 and IL28B-Related Single Nucleotide Polymorphisms

(2011) Martin Lagging et al.   PLoS One

Influenza virus aerosol exposure and analytical system for ferrets

(2011) K. M. Gustin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus infection kinetics: quantitative data and models

(2011) Amber M. Smith et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection Kinetics

(2011) Amber M. Smith et al.   PLoS Computational Biology

A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure

(2010) E Snoeck et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacodynamics of PEG-IFN-α-2a in HIV/HCV co-infected patients: Implications for treatment outcomes

(2010) Harel Dahari et al.   JOURNAL OF HEPATOLOGY

Hepatitis B Virus Kinetics under Antiviral Therapy Sheds Light on Differences in Hepatitis B e Antigen Positive and Negative Infections

(2010) Ruy M. Ribeiro et al.   JOURNAL OF INFECTIOUS DISEASES

A perspective on modelling hepatitis C virus infection

(2010) J. Guedj et al.   JOURNAL OF VIRAL HEPATITIS

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

(2010) H. Miao et al.   JOURNAL OF VIROLOGY

Dynamics of Influenza Virus Infection and Pathology

(2010) R. A. Saenz et al.   JOURNAL OF VIROLOGY

Population Modeling of Influenza A/H1N1 Virus Kinetics and Symptom Dynamics

(2010) L. Canini et al.   JOURNAL OF VIROLOGY

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

(2010) Min Gao et al.   NATURE

Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households

(2010) Benjamin J. Cowling et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus

(2010) L. Rong et al.   Science Translational Medicine

FluTE, a Publicly Available Stochastic Influenza Epidemic Simulation Model

(2010) Dennis L. Chao et al.   PLoS Computational Biology

A Multi-Variant, Viral Dynamic Model of Genotype 1 HCV to Assess the in vivo Evolution of Protease-Inhibitor Resistant Variants

(2010) Bambang S. Adiwijaya et al.   PLoS Computational Biology

Modeling HCV kinetics under therapy using PK and PD information

(2009) Emi Shudo et al.   Expert Opinion on Drug Metabolism & Toxicology

Towards a quantitative understanding of the within-host dynamics of influenza A infections

(2009) A. Handel et al.   Journal of the Royal Society Interface

Modeling complex decay profiles of hepatitis B virus during antiviral therapy

(2008) Harel Dahari et al.   HEPATOLOGY

Agent-based modeling of host–pathogen systems: The successes and challenges

(2008) Amy L. Bauer et al.   INFORMATION SCIENCES

Modeling amantadine treatment of influenza A virus in vitro

(2008) Catherine A.A. Beauchemin et al.   JOURNAL OF THEORETICAL BIOLOGY

Modelling the kinetics of hepatitis C virus RNA decline over 4 weeks of treatment with pegylated interferon α-2b

(2008) E. Shudo et al.   JOURNAL OF VIRAL HEPATITIS

An in-host model of acute infection: Measles as a case study

(2007) J.M. Heffernan et al.   THEORETICAL POPULATION BIOLOGY