Modeling Quasispecies and Drug Resistance in Hepatitis C Patients Treated with a Protease Inhibitor

Preliminary Study of Two Antiviral Agents for Hepatitis C Genotype 1

(2012) Anna S. Lok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel Therapies for Hepatitis C: Insights from the Structure of the Virus

(2011) Dahlene N. Fusco et al.   Annual Review of Medicine

Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders

(2011) Kazuaki Chayama et al.   HEPATOLOGY

Boceprevir for Untreated Chronic HCV Genotype 1 Infection

(2011) Fred Poordad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Response-Guided Telaprevir Combination Treatment for Hepatitis C Virus Infection

(2011) Kenneth E. Sherman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection

(2011) Bruce R. Bacon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance

(2011) M. H. Powdrill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Future of hepatitis C therapy

(2011) Gregory J. Dore et al.   Current Opinion in HIV and AIDS

Sustained Viral Response in a Hepatitis C Virus-Infected Chimpanzee via a Combination of Direct-Acting Antiviral Agents

(2010) David B. Olsen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Viral Mutation Rates

(2010) R. Sanjuan et al.   JOURNAL OF VIROLOGY

Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus

(2010) L. Rong et al.   Science Translational Medicine

A Multi-Variant, Viral Dynamic Model of Genotype 1 HCV to Assess the in vivo Evolution of Protease-Inhibitor Resistant Variants

(2010) Bambang S. Adiwijaya et al.   PLoS Computational Biology

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

(2009) Alexander Ploss et al.   NATURE

Telaprevir and Peginterferon with or without Ribavirin for Chronic HCV Infection

(2009) Christophe Hézode et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telaprevir with Peginterferon and Ribavirin for Chronic HCV Genotype 1 Infection

(2009) John G. McHutchison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Analysis of Hepatitis C Virus Infection Models with Hepatocyte Homeostasis

(2009) Timothy C. Reluga et al.   SIAM JOURNAL ON APPLIED MATHEMATICS

Synergy of a Hepatitis C Virus (HCV) NS4A Antagonist in Combination with HCV Protease and Polymerase Inhibitors

(2008) D. L. Wyles et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

(2008) M. F. McCown et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chronic Hepatitis B: Preventing, Detecting, and Managing Viral Resistance

(2008) Emmet B. Keeffe et al.   Clinical Gastroenterology and Hepatology

Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses?

(2008) V. Soriano et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antiviral effects and safety of telaprevir, peginterferon alfa-2a, and ribavirin for 28 days in hepatitis C patients

(2008) Eric Lawitz et al.   JOURNAL OF HEPATOLOGY

Natural Prevalence of Hepatitis C Virus Variants with Decreased Sensitivity to NS3·4A Protease Inhibitors in Treatment‐Naive Subjects

(2008) Doug J. Bartels et al.   JOURNAL OF INFECTIOUS DISEASES

Multistrain virus dynamics with mutations: a global analysis

(2008) P. De Leenheer et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE

Rates of evolutionary change in viruses: patterns and determinants

(2008) Siobain Duffy et al.   NATURE REVIEWS GENETICS

Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient

(2007) Maria Cubero et al.   VIROLOGY