Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease

Effects of local simvastatin-alendronate conjugate in preventing periodontitis bone loss

(2013) U. Price et al.   JOURNAL OF PERIODONTAL RESEARCH

Management of Cardiovascular Risk: The Importance of Meeting Lipid Targets

(2012) Antonio M. Gotto et al.   AMERICAN JOURNAL OF CARDIOLOGY

Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target

(2012) Junfei Jin et al.   CLINICAL IMMUNOLOGY

Protective Mechanisms of Simvastatin in Experimental Periodontal Disease

(2012) Roberta Dalcico et al.   JOURNAL OF PERIODONTOLOGY

Periodontitis and diabetes: a two-way relationship

(2011) P. M. Preshaw et al.   DIABETOLOGIA

Fluoxetine Inhibits Inflammatory Response and Bone Loss in a Rat Model of Ligature-Induced Periodontitis

(2011) Luciana S. Branco-de-Almeida et al.   JOURNAL OF PERIODONTOLOGY

Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: A mechanistic link between local and systemic inflammation

(2011) Ying Gu et al.   PHARMACOLOGICAL RESEARCH

Anti-inflammatory effect of MAPK phosphatase-1 local gene transfer in inflammatory bone loss

(2010) H Yu et al.   GENE THERAPY

Simvastatin Reduces Lipoprotein-associated Phospholipase A2 in Lipopolysaccharide-stimulated Human Monocyte–derived Macrophages Through Inhibition of the Mevalonate–Geranylgeranyl Pyrophosphate–RhoA-p38 Mitogen-activated Protein Kinase Pathway

(2010) Jun-Xian Song et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Clinical Effect of Subgingivally Delivered Simvastatin in the Treatment of Patients With Chronic Periodontitis: A Randomized Clinical Trial

(2010) Avani R. Pradeep et al.   JOURNAL OF PERIODONTOLOGY

Silencing Mitogen-Activated Protein Kinase-Activated Protein Kinase-2 Arrests Inflammatory Bone Loss

(2010) Q. Li et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Basic Science Review: Statin Therapy-Part I: The Pleiotropic Effects of Statins in Cardiovascular Disease

(2010) Benjamin Sadowitz et al.   Vascular and Endovascular Surgery

Simvastatin increases osteoblasts and osteogenic proteins in ovariectomized rats

(2009) M.-L. Ho et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway

(2009) M. S. Lee et al.   JOURNAL OF IMMUNOLOGY

Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand through modulation of NF-κB pathway

(2008) Kwang Seok Ahn et al.   INTERNATIONAL JOURNAL OF CANCER

Cardiovascular disease and periodontitis: an update on the associations and risk

(2008) Gösta Rutger Persson et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Simvastatin suppresses LPS-induced MMP-1 expression in U937 mononuclear cells by inhibiting protein isoprenylation-mediated ERK activation

(2008) Kamala P. Sundararaj et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Simvastatin therapy in cyclosporine A-induced alveolar bone loss in rats

(2008) P. O. Nassar et al.   JOURNAL OF PERIODONTAL RESEARCH

Simvastatin Suppresses the Progression of Experimentally Induced Cerebral Aneurysms in Rats

(2008) Tomohiro Aoki et al.   STROKE

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

(2008) Chao-Yung Wang et al.   TRENDS IN MOLECULAR MEDICINE

Statin use is associated with fewer periodontal lesions: A retrospective study

(2008) Otso Lindy et al.   BMC Oral Health