Yarrowia lipolytica: recent achievements in heterologous protein expression and pathway engineering

Effects of pyruvate dehydrogenase subunits overexpression on the α-ketoglutarate production in Yarrowia lipolytica WSH-Z06

(2014) Hongwei Guo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The influence of oxygen limitation for the production of succinic acid with recombinant strains of Yarrowia lipolytica

(2014) Benjamin Jost et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cloning, expression, and purification of insect (Sitophilus oryzae) alpha-amylase, able to digest granular starch, in Yarrowia lipolytica host

(2014) Ewelina Celińska et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Growth and neutral lipid synthesis by Yarrowia lipolytica on various carbon substrates under nutrient-sufficient and nutrient-limited conditions

(2014) Ryan Sestric et al.   BIORESOURCE TECHNOLOGY

Using planktonic microorganisms to supply the unpurified multi-copper oxidases laccase and copper efflux oxidases at a biofuel cell cathode

(2014) Sabine Sané et al.   BIORESOURCE TECHNOLOGY

Engineering towards a complete heterologous cellulase secretome in Yarrowia lipolytica reveals its potential for consolidated bioprocessing

(2014) Hui Wei et al.   Biotechnology for Biofuels

One-step integration of multiple genes into the oleaginous yeast Yarrowia lipolytica

(2014) Shuliang Gao et al.   BIOTECHNOLOGY LETTERS

Fatty Aldehyde Dehydrogenase Multigene Family Involved in the Assimilation ofn-Alkanes inYarrowia lipolytica

(2014) Ryo Iwama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced lipid accumulation in the yeast Yarrowia lipolytica by over-expression of ATP:citrate lyase from Mus musculus

(2014) Huaiyuan Zhang et al.   JOURNAL OF BIOTECHNOLOGY

Construction of a Highly Active Xylanase Displaying Oleaginous Yeast: Comparison of Anchoring Systems

(2014) Sophie Duquesne et al.   PLoS One

Heterologous Expression of Xylanase Enzymes in Lipogenic Yeast Yarrowia lipolytica

(2014) Wei Wang et al.   PLoS One

Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production

(2014) John Blazeck et al.   Nature Communications

Production of Lycopene in the Non-Carotenoid-Producing Yeast Yarrowia lipolytica

(2013) Falk Matthäus et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineering the α-ketoglutarate overproduction from raw glycerol by overexpression of the genes encoding NADP+-dependent isocitrate dehydrogenase and pyruvate carboxylase in Yarrowia lipolytica

(2013) Venelina Yovkova et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Industrial wastes as a promising renewable source for production of microbial lipid and direct transesterification of the lipid into biodiesel

(2013) Benjamas Cheirsilp et al.   BIORESOURCE TECHNOLOGY

Metabolism of Hydrophobic Carbon Sources and Regulation of It inn-Alkane-Assimilating YeastYarrowia lipolytica

(2013) Ryouichi FUKUDA   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Yarrowia lipolytica: Safety assessment of an oleaginous yeast with a great industrial potential

(2013) Marizeth Groenewald et al.   CRITICAL REVIEWS IN MICROBIOLOGY

The safety of β-carotene from Yarrowia lipolytica

(2013) Daniel Grenfell-Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Food-related applications of Yarrowia lipolytica

(2013) Smita S. Zinjarde   FOOD CHEMISTRY

Heterologous production of pentane in the oleaginous yeast Yarrowia lipolytica

(2013) John Blazeck et al.   JOURNAL OF BIOTECHNOLOGY

Optimized invertase expression and secretion cassette for improving Yarrowia lipolytica growth on sucrose for industrial applications

(2013) Zbigniew Lazar et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Cell-surface expression of Aspergillus saitoi-derived functional α-1,2-mannosidase on Yarrowia lipolytica for glycan remodeling

(2013) Hye Yun Moon et al.   JOURNAL OF MICROBIOLOGY

A novel multigene expression construct for modification of glycerol metabolism in Yarrowia lipolytica

(2013) Ewelina Celińska et al.   Microbial Cell Factories

Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica

(2013) Zhixiong Xue et al.   NATURE BIOTECHNOLOGY

Generalizing a hybrid synthetic promoter approach in Yarrowia lipolytica

(2012) John Blazeck et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Variation of the by-product spectrum during α-ketoglutaric acid production from raw glycerol by overexpression of fumarase and pyruvate carboxylase genes in Yarrowia lipolytica

(2012) Christina Otto et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhanced alpha-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by regulation of the pyruvate carboxylation pathway

(2012) Xiaoxia Yin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering and production of laccase from Trametes versicolor in the yeast Yarrowia lipolytica

(2012) Monnat Theerachat et al.   BIORESOURCE TECHNOLOGY

Tunable nano-oleosomes derived from engineeredYarrowia lipolytica

(2012) Zhenlin Han et al.   BIOTECHNOLOGY AND BIOENGINEERING

Efficient homologous recombination with short length flanking fragments in Ku70 deficient Yarrowia lipolytica strains

(2012) Jonathan Verbeke et al.   BIOTECHNOLOGY LETTERS

A genome-scale metabolic model of the lipid-accumulating yeast Yarrowia lipolytica

(2012) Nicolas Loira et al.   BMC Systems Biology

Enhanced α-ketoglutarate production in Yarrowia lipolytica WSH-Z06 by alteration of the acetyl-CoA metabolism

(2012) Jingwen Zhou et al.   JOURNAL OF BIOTECHNOLOGY

Both Decrease in ACL1 Gene Expression and Increase in ICL1 Gene Expression in Marine-Derived Yeast Yarrowia lipolytica Expressing INU1 Gene Enhance Citric Acid Production from Inulin

(2012) Xiao-Yan Liu et al.   MARINE BIOTECHNOLOGY

Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production

(2012) Mitchell Tai et al.   METABOLIC ENGINEERING

Steroid biotransformations in biphasic systems with Yarrowia lipolytica expressing human liver cytochrome P450 genes

(2012) Andreas Braun et al.   Microbial Cell Factories

Engineering the yeast Yarrowia lipolytica for the production of therapeutic proteins homogeneously glycosylated with Man8GlcNAc2 and Man5GlcNAc2

(2012) Karen De Pourcq et al.   Microbial Cell Factories

A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes

(2012) Petra Tiels et al.   NATURE BIOTECHNOLOGY

Engineering Yarrowia lipolytica to Produce Glycoproteins Homogeneously Modified with the Universal Man3GlcNAc2 N-Glycan Core

(2012) Karen De Pourcq et al.   PLoS One

Yarrowia lipolytica

(2012) Jean-Marc Nicaud   YEAST

Tuning Gene Expression in Yarrowia lipolytica by a Hybrid Promoter Approach

(2011) John Blazeck et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

How is the reactivity of laccase affected by single-point mutations? Engineering laccase for improved activity towards sterically demanding substrates

(2011) Carlo Galli et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering polyhydroxyalkanoate content and monomer composition in the oleaginous yeast Yarrowia lipolytica by modifying the ß-oxidation multifunctional protein

(2011) Ramdane Haddouche et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Efficient cell surface display of Lip2 lipase using C-domains of glycosylphosphatidylinositol-anchored cell wall proteins of Yarrowia lipolytica

(2011) Evgeniya Y. Yuzbasheva et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Construction of a whole-cell catalyst displaying a fungal lipase for effective treatment of oily wastewaters

(2011) Huiting Song et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Involvement of the G3P shuttle and β-oxidation pathway in the control of TAG synthesis and lipid accumulation in Yarrowia lipolytica

(2011) Thierry Dulermo et al.   METABOLIC ENGINEERING

Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica

(2011) Najla Gasmi et al.   Microbial Cell Factories

Direct conversion of inulin into single cell protein by the engineered Yarrowia lipolytica carrying inulinase gene

(2011) Wei Cui et al.   PROCESS BIOCHEMISTRY

Production of recombinant Rhizopus oryzae lipase by the yeast Yarrowia lipolytica results in increased enzymatic thermostability

(2011) Tigran V. Yuzbashev et al.   PROTEIN EXPRESSION AND PURIFICATION

Engineering Yarrowia lipolytica to express secretory invertase with strong FBA1IN promoter

(2011) Seung-Pyo Hong et al.   YEAST

New Efficient Recombinant Expression System To Engineer Candida antarctica Lipase B

(2010) S. Emond et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Essential Role of YlMPO1, a NovelYarrowia lipolyticaHomologue ofSaccharomyces cerevisiae MNN4, in Mannosylphosphorylation of N- and O-Linked Glycans

(2010) Jeong-Nam Park et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Overexpression of alpha-ketoglutarate dehydrogenase in Yarrowia lipolytica and its effect on production of organic acids

(2010) Martina Holz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Surface display of acid protease on the cells of Yarrowia lipolytica for milk clotting

(2010) Xin-Jun Yu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A molecular approach to optimize hIFN α2b expression and secretion in Yarrowia lipolytica

(2010) Najla Gasmi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

From structure and functions of steroidogenic enzymes to new technologies of gene engineering

(2010) L. A. Novikova et al.   BIOCHEMISTRY-MOSCOW

Overexpression of acid protease of Saccharomycopsis fibuligera in Yarrowia lipolytica and characterization of the recombinant acid protease for skimmed milk clotting

(2010) Xin-Jun Yu et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Roles of multiple acyl-CoA oxidases in the routing of carbon flow towards β-oxidation and polyhydroxyalkanoate biosynthesis in Yarrowia lipolytica

(2010) Ramdane Haddouche et al.   FEMS YEAST RESEARCH

Heterologous expression of Thermobifida fusca thermostable alpha-amylase in Yarrowia lipolytica and its application in boiling stable resistant sago starch preparation

(2010) Chao-Hsun Yang et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Inulin hydrolysis and citric acid production from inulin using the surface-engineered Yarrowia lipolytica displaying inulinase

(2010) Xiao-Yan Liu et al.   METABOLIC ENGINEERING

Expression of inulinase gene in the oleaginous yeast Yarrowia lipolytica and single cell oil production from inulin-containingmaterials

(2010) Chun-Hai Zhao et al.   METABOLIC ENGINEERING

Co-expression of heterologous desaturase genes in Yarrowia lipolytica

(2010) Lu-Te Chuang et al.   New Biotechnology

The ‘LipoYeasts’ project: using the oleaginous yeast Yarrowia lipolytica in combination with specific bacterial genes for the bioconversion of lipids, fats and oils into high-value products

(2010) Julia S. Sabirova et al.   Microbial Biotechnology

Environmental and industrial applications of Yarrowia lipolytica

(2009) Ashok V. Bankar et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Yarrowia lipolytica: A model and a tool to understand the mechanisms implicated in lipid accumulation

(2009) Athanasios Beopoulos et al.   BIOCHIMIE

Cell-surface display of the active mannanase inYarrowia lipolyticawith a novel surface-display system

(2009) Xiao‑Song Yang et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Heterologous Expression and Optimized Production of an Aspergillus aculeatus Endo-1,4-β-mannanase in Yarrowia lipolytica

(2009) Robyn Roth et al.   MOLECULAR BIOTECHNOLOGY

Yarrowia lipolytica as a model for bio-oil production

(2009) Athanasios Beopoulos et al.   PROGRESS IN LIPID RESEARCH

Control of Lipid Accumulation in the Yeast Yarrowia lipolytica

(2008) A. Beopoulos et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Aconitase overexpression changes the product ratio of citric acid production by Yarrowia lipolytica

(2008) Martina Holz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Multi-copy expression and fed-batch production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica

(2008) Dheepak Maharajh et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effect of an exponential feeding regime on the production ofRhodotorula araucariaeepoxide hydrolase inYarrowia lipolytica

(2008) D. Maharajh et al.   LETTERS IN APPLIED MICROBIOLOGY

Alkaline Protease Gene Cloning from the Marine Yeast Aureobasidium pullulans HN2-3 and the Protease Surface Display on Yarrowia lipolytica for Bioactive Peptide Production

(2008) Xiumei Ni et al.   MARINE BIOTECHNOLOGY

Cloning, Characterization, and Expression of the Gene Encoding Alkaline Protease in the Marine Yeast Aureobasidium pullulans 10

(2008) Xiumei Ni et al.   MARINE BIOTECHNOLOGY

Synthesis of a variety of optically active hydroxylated heterocyclic compounds using epoxide hydrolase technology

(2008) Daniel P. Pienaar et al.   TETRAHEDRON LETTERS

Construction of a new plasmid for surface display on cells of Yarrowia lipolytica

(2007) Lixi Yue et al.   JOURNAL OF MICROBIOLOGICAL METHODS