Article
Obstetrics & Gynecology
J. Stanhiser, A. M. Z. Jukic, D. R. McConnaughey, A. Z. Steiner
Summary: The study found that self-reported use of omega-3 fatty acid supplements was associated with an increased probability of conceiving.
HUMAN REPRODUCTION
(2022)
Article
Food Science & Technology
Dimitra Karageorgou, Ulrika Rova, Paul Christakopoulos, Petros Katapodis, Leonidas Matsakas, Alok Patel
Summary: This review summarizes the role of omega-3 and omega-6 fatty acids, determined by chain length, saturation degree, and position of double bonds, in human health. It highlights oleaginous microalgae as a reliable, economical, and sustainable source of these fatty acids. Humans cannot synthesize these fatty acids and need to absorb them through the diet. The demand for microbial omega-3 fatty acids is increasing due to the growing prevalence of cardiovascular diseases and changing dietary preferences. The importance of a healthy immune system, especially following the COVID-19 pandemic, has further strengthened the market for omega-3 fatty acids.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Sport Sciences
Maja Tomczyk, Zbigniew Jost, Maciej Chroboczek, Robert Urbanski, Philip C. Calder, Helena L. Fisk, Mateusz Sprengel, Jedrzej Antosiewicz
Summary: The study aimed to investigate the effects of 12 wk of omega-3 fatty acid supplementation during endurance training on omega-3 index (O3I) and indicators of running performance in amateur long-distance runners. The results showed a significant increase in O3I, improvements in (V) over dotO(2peak) and running economy, but no significant effect on the 1500-m run trial time.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Review
Nutrition & Dietetics
Maha Timraz, Ahmad Binmahfoz, Terry J. Quinn, Emilie Combet, Stuart R. Gray
Summary: The aim of this study was to examine the effects of LCn-3 PUFA supplementation on muscle strength in older individuals. A systematic literature review was conducted, and five relevant studies were included. The results showed that LCn-3 PUFA supplementation did not significantly improve grip strength compared to the control group.
Article
Nutrition & Dietetics
Grace Austin, Jessica J. A. Ferguson, Rohith N. Thota, Harjinder Singh, Tracy Burrows, Manohar L. Garg
Summary: The study showed that LCn-3PUFA with or without MCSFA, but not MCSFA alone, are effective in reducing postprandial triglycerides in healthy individuals.
CLINICAL NUTRITION
(2021)
Article
Chemistry, Medicinal
Lena Stiefvatter, Katja Lehnert, Konstantin Frick, Alexander Montoya-Arroyo, Jan Frank, Walter Vetter, Ulrike Schmid-Staiger, Stephan C. Bischoff
Summary: The microalgae Phaeodactylum tricornutum (PT) is a valuable source of nutrients such as proteins, polyunsaturated omega-3 fatty acids (n-3 PUFA), particularly eicosapentaenoic acid (EPA), carotenoids like fucoxanthin (FX), and beta-glucans. Intake of PT leads to an increase in n-3 PUFA and EPA levels, while also decreasing the n-6:n-3 ratio in plasma. The study shows that PT is a safe and effective source of EPA and other nutrients, suggesting its potential as a sustainable food source.
Article
Cardiac & Cardiovascular Systems
Richard L. Weinberg, Robert D. Brook, Melvyn Rubenfire, Kim A. Eagle
Summary: Omega-3 polyunsaturated fatty acids play a key role in heart-healthy diet, and can be obtained through fatty fish consumption or fish oil supplementation. They not only treat hypertriglyceridemia, but also prevent cardiovascular events, with additional benefits such as reducing inflammation and improving plaque stability.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Food Science & Technology
Michael E. Tlusty
Summary: The study found that while food-based dietary guidelines are an effective means to encourage healthy eating habits, their impact on promoting consumption of healthy fish species, particularly those high in long-chain omega-3 fatty acids, is limited. In the United States, the predominant consumption of shrimp does not significantly contribute to dietary omega-3 consumption.
Review
Cardiac & Cardiovascular Systems
Baris Gencer, Luc Djousse, Omar T. Al-Ramady, Nancy R. Cook, JoAnn E. Manson, Christine M. Albert
Summary: In randomized controlled trials examining cardiovascular outcomes, supplementation of marine -3 fatty acids was associated with an increased risk of atrial fibrillation (AF). The risk appeared to be greater in trials testing >1 g/d.
Article
Multidisciplinary Sciences
Lars Dalheim, Jon Brage Svenning, Ragnar Ludvig Olsen
Summary: This study compared the in vitro intestinal digestion of different LC n-3 PUFA supplements and found varying levels of increase in free fatty acids during digestion.Monounsaturated and saturated fatty acids were more easily released than polyunsaturated fatty acids in all five oils, with cod liver oil experiencing the highest increase in free fatty acids.
Review
Food Science & Technology
Arti Kumari, Sunil Pabbi, Aruna Tyagi
Summary: Omega-3 fatty acids, particularly EPA and DHA, are essential for human health and must be obtained through diet or supplementation. Traditional sources include vegetable oils and fish, but concerns about sustainability and contamination have led to the exploration of alternative sources, such as microalgae. This review discusses strategies for enhancing EPA and DHA production in microalgae, including strain selection, cultivation optimization, and genetic engineering. These approaches pave the way for large-scale production of EPA and DHA to promote human health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Nutrition & Dietetics
Lara T. Meital, Karl Schulze, Rebecca Magee, Jill O'Donnell, Pankaj Jha, Chaim Y. Meital, Rebecca Donkin, Tom G. Bailey, Christopher D. Askew, Fraser D. Russell
Summary: Abdominal aortic aneurysm (AAA) is a vascular disease involving permanent focal dilation of the abdominal aorta that can lead to catastrophic rupture. Supplementation with long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFAs) may decrease aortic stiffness in patients with AAA, but the clinical implications are yet to be fully elucidated.
Review
Chemistry, Medicinal
Alessandro Colletti, Giancarlo Cravotto, Valentina Citi, Alma Martelli, Lara Testai, Arrigo F. G. Cicero
Summary: Krill, a small marine crustacean from the Antarctic Ocean, plays an important role in the marine ecosystem as a food source for most fish and is rich in omega-3 fatty acids. Solvent extraction is the most common method to obtain krill oil, which has shown a range of health benefits in clinical trials.
Article
Biochemistry & Molecular Biology
Flavie Courtaut, Virginie Aires, Niyazi Acar, Lionel Bretillon, Ida Chiara Guerrera, Cerina Chhuon, Jean-Paul Pais De Barros, Celine Olmiere, Dominique Delmas
Summary: The study found that supplementation with Resvega(R) significantly reduced laser-induced choroidal neovascularization (CNV) in mice compared with supplementations containing omega-3 or resveratrol alone. Proteomic approach confirmed that Resvega(R) could counteract the progression of AMD through a pleiotropic effect targeting key regulators of neoangiogenesis in retina cells in vivo.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nutrition & Dietetics
Welma Stonehouse, Bradley Klingner, Rachel Tso, Pey Sze Teo, Netsanet Shiferaw Terefe, Ciaran G. Forde
Summary: This study evaluated the bioavailability of omega-3 LCPUFA from foods enriched with vegetable-based encapsulated algal oil among Australian and Singaporean populations. The results showed that this delivery system did not affect the bioavailability of omega-3 LCPUFA in healthy young men from both ethnic groups.
EUROPEAN JOURNAL OF NUTRITION
(2022)
