Linking Traumatic Brain Injury to Chronic Traumatic Encephalopathy: Identification of Potential Mechanisms Leading to Neurofibrillary Tangle Development

Abnormal Hyperphosphorylation of Tau: Sites, Regulation, and Molecular Mechanism of Neurofibrillary Degeneration

(2018) Jian-Zhi Wang et al.   JOURNAL OF ALZHEIMERS DISEASE

PET Scanning of Brain Tau in Retired National Football League Players: Preliminary Findings

(2013) Gary W. Small et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Clinical correlates in an experimental model of repetitive mild brain injury

(2013) Rebekah Mannix et al.   ANNALS OF NEUROLOGY

[Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3β inhibition in a mouse model of intracerebral hemorrhage

(2013) Tao Wang et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibitory effects of p38 inhibitor against mitochondrial dysfunction in the early brain injury after subarachnoid hemorrhage in mice

(2013) Liyong Huang et al.   BRAIN RESEARCH

Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog

(2013) Swetlana Sirko et al.   Cell Stem Cell

Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing

(2013) María Elena Avale et al.   HUMAN MOLECULAR GENETICS

Military- and Sports-Related Mild Traumatic Brain Injury: Clinical Presentation, Management, and Long-Term Consequences

(2013) Elaine R. Peskind et al.   JOURNAL OF CLINICAL PSYCHIATRY

Upregulation of CRM1 Relates to Neuronal Apoptosis after Traumatic Brain Injury in Adult Rats

(2013) Aihong Li et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Role of subconcussion in repetitive mild traumatic brain injury

(2013) Julian E. Bailes et al.   JOURNAL OF NEUROSURGERY

Brain Injury: Neuro-Inflammation, Cognitive Deficit, and Magnetic Resonance Imaging in a Model of Blast Induced Traumatic Brain Injury

(2013) Paul Tompkins et al.   JOURNAL OF NEUROTRAUMA

Screening of Biochemical and Molecular Mechanisms of Secondary Injury and Repair in the Brain after Experimental Blast-Induced Traumatic Brain Injury in Rats

(2013) Patrick M. Kochanek et al.   JOURNAL OF NEUROTRAUMA

Involvement of Extracellular Signal Regulated Kinases in Traumatic Brain Injury-Induced Depression in Rodents

(2013) Jinn-Rung Kuo et al.   JOURNAL OF NEUROTRAUMA

Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features

(2013) Giacomina Rossi et al.   NEUROBIOLOGY OF AGING

β-Amyloid impairs the regulation of N-methyl-D-aspartate receptors by glycogen synthase kinase 3

(2013) Yulei Deng et al.   NEUROBIOLOGY OF AGING

Spatiotemporal Patterns and Essential Role of MSK1 Expression After Rat Spinal Cord Injury

(2013) Zhen Li et al.   NEUROCHEMICAL RESEARCH

The effect of NADPH-oxidase inhibitor apocynin on cognitive impairment induced by moderate lateral fluid percussion injury: Role of inflammatory and oxidative brain damage

(2013) Ana Paula Oliveira Ferreira et al.   NEUROCHEMISTRY INTERNATIONAL

Rapamycin decreases tau phosphorylation at Ser214 through regulation of cAMP-dependent kinase

(2013) Yudong Liu et al.   NEUROCHEMISTRY INTERNATIONAL

Chronic traumatic encephalopathy – neuropathology in athletes and war veterans

(2013) Nelli Lakis et al.   NEUROLOGICAL RESEARCH

Clinical presentation of chronic traumatic encephalopathy

(2013) R. A. Stern et al.   NEUROLOGY

Distinct activation profiles in microglia of different ages: A systematic study in isolated embryonic to aged microglial cultures

(2013) A.Y. Lai et al.   NEUROSCIENCE

Distinct patterns of expression of traumatic brain injury biomarkers after blast exposure: Role of compromised cell membrane integrity

(2013) Peethambaran Arun et al.   NEUROSCIENCE LETTERS

Neuroinflammation: The role and consequences

(2013) Monty Lyman et al.   NEUROSCIENCE RESEARCH

Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments

(2013) Margaret K. King et al.   PHARMACOLOGY & THERAPEUTICS

Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model

(2013) Sandra A. Acosta et al.   PLoS One

RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse

(2013) Urmi Bandyopadhyay et al.   PLoS One

Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits following Traumatic Brain Injury in Mice

(2013) Sindhu K. Madathil et al.   PLoS One

Correction: In Vivo Imaging with Fluorescent Smart Probes to Assess Treatment Strategies for Acute Pancreatitis

(2013) Abhiruchi Agarwal et al.   PLoS One

GADD34 induces cell death through inactivation of Akt following traumatic brain injury

(2013) J M Farook et al.   Cell Death & Disease

Molecular mechanisms of cognitive dysfunction following traumatic brain injury

(2013) Kendall R. Walker et al.   Frontiers in Aging Neuroscience

Microglia Activation as a Biomarker for Traumatic Brain Injury

(2013) Diana G. Hernandez-Ontiveros et al.   Frontiers in Neurology

Hyperphosphorylation-Induced Tau Oligomers

(2013) Khalid Iqbal et al.   Frontiers in Neurology

Are Tau Aggregates Toxic or Protective in Tauopathies?

(2013) Catherine M. Cowan et al.   Frontiers in Neurology

Tau protein kinases: Involvement in Alzheimer's disease

(2012) Ludovic Martin et al.   AGEING RESEARCH REVIEWS

Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death

(2012) Ting Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury

(2012) M. E. Shenton et al.   Brain Imaging and Behavior

Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo

(2012) Yongbo Zhao et al.   EXPERIMENTAL NEUROLOGY

Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6)

(2012) Michaeline L. Hebron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The neurotoxic effect of astrocytes activated with toll-like receptor ligands

(2012) Di Ma et al.   JOURNAL OF NEUROIMMUNOLOGY

Inhibition of JNK by a Peptide Inhibitor Reduces Traumatic Brain Injury–Induced Tauopathy in Transgenic Mice

(2012) Hien T. Tran et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Estrone Is Neuroprotective in Rats after Traumatic Brain Injury

(2012) Joshua W. Gatson et al.   JOURNAL OF NEUROTRAUMA

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

(2012) Alok Kumar et al.   NEUROBIOLOGY OF AGING

Combination therapy with glucagon and a novel plasminogen activator inhibitor-1-derived peptide enhances protection against impaired cerebrovasodilation during hypotension after traumatic brain injury through inhibition of ERK and JNK MAPK

(2012) William M Armstead et al.   NEUROLOGICAL RESEARCH

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Review: The long-term consequences of microglial activation following acute traumatic brain injury

(2012) C. Smith   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Scriptaid, a Novel Histone Deacetylase Inhibitor, Protects Against Traumatic Brain Injury via Modulation of PTEN and AKT Pathway

(2012) Guohua Wang et al.   Neurotherapeutics

A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology

(2012) Takenari Yamashita et al.   Nature Communications

Frontier of Epilepsy Research - mTOR signaling pathway

(2011) Chang-Hoon Cho   EXPERIMENTAL AND MOLECULAR MEDICINE

Selective CDK Inhibitor Limits Neuroinflammation and Progressive Neurodegeneration after Brain Trauma

(2011) Shruti V Kabadi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A mouse model of human repetitive mild traumatic brain injury

(2011) Michael J. Kane et al.   JOURNAL OF NEUROSCIENCE METHODS

3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP

(2011) Krishnamoorthy Srinivasan et al.   LIFE SCIENCES

Does IGF-1 administration after a mild traumatic brain injury in mice activate the adaptive arm of ER stress?

(2011) Vardit Rubovitch et al.   NEUROCHEMISTRY INTERNATIONAL

tPA contributes to impaired NMDA cerebrovasodilation after traumatic brain injury through activation of JNK MAPK

(2011) William M Armstead et al.   NEUROLOGICAL RESEARCH

CR8, a Selective and Potent CDK Inhibitor, Provides Neuroprotection in Experimental Traumatic Brain Injury

(2011) Shruti V. Kabadi et al.   Neurotherapeutics

Involvement of the Glycogen Synthase Kinase-3 Signaling Pathway in TBI Pathology and Neurocognitive Outcome

(2011) Pramod K. Dash et al.   PLoS One

The National Football League and Concussion: Leading a Culture Change in Contact Sports

(2011) Richard G. Ellenbogen et al.   World Neurosurgery

Long-term Consequences of Repetitive Brain Trauma: Chronic Traumatic Encephalopathy

(2011) Robert A. Stern et al.   PM&R

Endoplasmic reticulum protein BI-1 modulates unfolded protein response signaling and protects against stroke and traumatic brain injury

(2010) Maryla Krajewska et al.   BRAIN RESEARCH

Chronic Traumatic Encephalopathy: A Potential Late Effect of Sport-Related Concussive and Subconcussive Head Trauma

(2010) Brandon E. Gavett et al.   CLINICS IN SPORTS MEDICINE

Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition

(2010) Søren M. Johnson et al.   JOURNAL OF CLINICAL INVESTIGATION

Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer’s disease model

(2010) Niall M. Corcoran et al.   JOURNAL OF CLINICAL NEUROSCIENCE

TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy

(2010) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton

(2010) A. A. Kramerov et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

PKC activator therapeutic for mild traumatic brain injury in mice

(2010) Ofer Zohar et al.   NEUROBIOLOGY OF DISEASE

Microglia signaling as a target of donepezil

(2010) Jaegyu Hwang et al.   NEUROPHARMACOLOGY

Icariin attenuates β-amyloid-induced neurotoxicity by inhibition of tau protein hyperphosphorylation in PC12 cells

(2010) Ke-Wu Zeng et al.   NEUROPHARMACOLOGY

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3ζ protein

(2009) Golam Sadik et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

(2009) Ann C. McKee et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Expression of Protein Phosphatase 2B (Calcineurin) Subunit A Isoforms in Rat Hippocampus after Traumatic Brain Injury

(2009) James W. Bales et al.   JOURNAL OF NEUROTRAUMA

Apolipoprotein E-deficient mice are more vulnerable to ER stress after transient forebrain ischemia

(2009) Nobuhiro Osada et al.   NEUROCHEMISTRY INTERNATIONAL

Crosstalk between Spinal Astrocytes and Neurons in Nerve Injury-Induced Neuropathic Pain

(2009) Wei Wang et al.   PLoS One

Formal total synthesis of (−)-balanol: a potent PKC inhibitor

(2009) Srinivasarao Yaragorla et al.   TETRAHEDRON LETTERS

Roscovitine Reduces Neuronal Loss, Glial Activation, and Neurologic Deficits after Brain Trauma

(2008) Genell D Hilton et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A possible link between astrocyte activation and tau nitration in Alzheimer's disease

(2008) Juan F. Reyes et al.   NEUROBIOLOGY OF DISEASE

Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase

(2007) Chih-Lin Kuo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY