Mesenchymal progenitor cells combined with pentosan polysulfate mediating disc regeneration at the time of microdiscectomy: a preliminary study in an ovine model

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex

(2012) Linda Troeberg et al.   BIOCHEMICAL JOURNAL

Immunoselected STRO-3+mesenchymal precursor cells and restoration of the extracellular matrix of degenerate intervertebral discs

(2012) Peter Ghosh et al.   JOURNAL OF NEUROSURGERY-SPINE

Percutaneous Image-guided Delivery for the Transplantation of Mesenchymal Stem Cells in the Setting of Degenerated Intervertebral Discs

(2012) J. David Prologo et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Intervertebral Disc-Derived Stem Cells

(2012) W. Mark Erwin et al.   SPINE

Lateral Surgical Approach to Lumbar Intervertebral Discs in an Ovine Model

(2012) David Oehme et al.   TheScientificWorldJOURNAL

Intervertebral disc disease in dogs – Part 1: A new histological grading scheme for classification of intervertebral disc degeneration in dogs

(2012) N. Bergknut et al.   VETERINARY JOURNAL

Phosphate and CVD

(2011) Gary E. Striker et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fibrin glue as the cell-delivery vehicle for mesenchymal stromal cells in regenerative medicine

(2011) Xiuwen Wu et al.   CYTOTHERAPY

Long-term back pain after a single-level discectomy for radiculopathy: incidence and health care cost analysis

(2011) Scott L. Parker et al.   JOURNAL OF NEUROSURGERY-SPINE

Transplantation of mesenchymal stem cells and nucleus pulposus cells in a degenerative disc model in rabbits: a comparison of 2 cell types as potential candidates for disc regeneration

(2011) Ganjun Feng et al.   JOURNAL OF NEUROSURGERY-SPINE

Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation

(2011) Gianluca Vadalà et al.   Journal of Tissue Engineering and Regenerative Medicine

Inhibitory Effects of Pentosan Polysulfate Sodium on MAP-Kinase Pathway and NF-^|^kappa;B Nuclear Translocation in Canine Chondrocytes In Vitro

(2011) Takafumi SUNAGA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice

(2011) Jin Wu et al.   LABORATORY INVESTIGATION

Regeneration of the Intervertebral Disc With Nucleus Pulposus Cell-Seeded Collagen II/Hyaluronan/Chondroitin-6-Sulfate Tri-Copolymer Constructs in a Rabbit Disc Degeneration Model

(2011) Bo Huang et al.   SPINE

Mechanical Destabilization Induced by Controlled Annular Incision of the Intervertebral Disc Dysregulates Metalloproteinase Expression and Induces Disc Degeneration

(2011) James Melrose et al.   SPINE

Porcine Intervertebral Disc Repair Using Allogeneic Juvenile Articular Chondrocytes or Mesenchymal Stem Cells

(2011) Frank L. Acosta et al.   TISSUE ENGINEERING PART A

Regeneration of intervertebral discs in a rat disc degeneration model by implanted adipose-tissue-derived stromal cells

(2010) Je Hoon Jeong et al.   ACTA NEUROCHIRURGICA

Effects of implantation of bone marrow mesenchymal stem cells, disc distraction and combined therapy on reversing degeneration of the intervertebral disc

(2010) H. T. Hee et al.   JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME

Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model

(2010) Kenji Serigano et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Cervical motion preservation using mesenchymal progenitor cells and pentosan polysulfate, a novel chondrogenic agent: preliminary study in an ovine model

(2010) Tony Goldschlager et al.   Neurosurgical Focus

Transplanted mesenchymal stem cells with pure fibrinous gelatin-transforming growth factor-β1 decrease rabbit intervertebral disc degeneration

(2010) Huilin Yang et al.   Spine Journal

Structured coculture of stem cells and disc cells prevent disc degeneration in a rat model

(2010) Aliza A. Allon et al.   Spine Journal

Experimental Intervertebral Disc Regeneration with Tissue-Engineered Composite in a Canine Model

(2010) Di-Ke Ruan et al.   TISSUE ENGINEERING PART A

Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells

(2010) Peter Ghosh et al.   ARTHRITIS RESEARCH & THERAPY

Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits

(2010) Takashi Miyamoto et al.   ARTHRITIS RESEARCH & THERAPY

Human mesenchymal stem cells implantation into the degenerated coccygeal disc of the rat

(2009) Je Hoon Jeong et al.   CYTOTECHNOLOGY

Methods to monitor distribution and metabolic activity of mesenchymal stem cells following in vivo injection into nucleotomized porcine intervertebral discs

(2009) G. W. Omlor et al.   EUROPEAN SPINE JOURNAL

TNF-α Induces MMP2 Gelatinase Activity and MT1-MMP Expression in an In Vitro Model of Nucleus Pulposus Tissue Degeneration

(2009) Cheryle A. Séguin et al.   SPINE

Transplantation of Human Mesenchymal Stems Cells Into Intervertebral Discs in a Xenogeneic Porcine Model

(2009) Helena B. Henriksson et al.   SPINE

Heat Shock Protein-90 beta Is Expressed at the Surface of Multipotential Mesenchymal Precursor Cells: Generation of a Novel Monoclonal Antibody, STRO-4, With Specificity for Mesenchymal Precursor Cells From Human and Ovine Tissues

(2009) Stan Gronthos et al.   STEM CELLS AND DEVELOPMENT

Effect of Severity of Intervertebral Disc Injury on Mesenchymal Stem Cell-Based Regeneration

(2008) Grace Ho et al.   CONNECTIVE TISSUE RESEARCH

Cell transplantation in lumbar spine disc degeneration disease

(2008) C. Hohaus et al.   EUROPEAN SPINE JOURNAL

Gene therapy approach for disc degeneration and associated spinal disorders

(2008) Kotaro Nishida et al.   EUROPEAN SPINE JOURNAL

Biological repair of the degenerated intervertebral disc by the injection of growth factors

(2008) Koichi Masuda   EUROPEAN SPINE JOURNAL

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases

(2008) Linda Troeberg et al.   FASEB JOURNAL

Calcium pentosan polysulfate directly inhibits enzymatic activity of ADAMTS4 (aggrecanase-1) in osteoarthritic chondrocytes

(2008) Masayuki Takizawa et al.   FEBS LETTERS

The fate of transplanted xenogeneic bone marrow-derived stem cells in rat intervertebral discs

(2008) Aiqun Wei et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Transplantation of mesenchymal stem cells in a canine disc degeneration model

(2008) Akihiko Hiyama et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Chondrogenesis, bone morphogenetic protein-4 and mesenchymal stem cells

(2008) N.D. Miljkovic et al.   OSTEOARTHRITIS AND CARTILAGE

Feasibility of a stem cell therapy for intervertebral disc degeneration

(2007) Satoshi Sobajima et al.   Spine Journal