PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation

Pink1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced akt and increased p38 mapk activation, and downregulation of egfr

(2013) Insup Choi et al.   GLIA

Tissue transglutaminase cross-links beclin 1 and regulates autophagy in MPP+-treated human SH-SY5Y cells

(2013) Robin Verhaar et al.   NEUROCHEMISTRY INTERNATIONAL

Genetics of Parkinson's Disease

(2013) C. Klein et al.   Cold Spring Harbor Perspectives in Medicine

Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

(2012) Yi Wang et al.   BMC CANCER

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

(2012) M D'Eletto et al.   CELL DEATH AND DIFFERENTIATION

PINK1 stimulates interleukin-1β-mediated inflammatory signaling via the positive regulation of TRAF6 and TAK1

(2012) Hyun Jung Lee et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transglutaminase 2 Promotes Both Caspase-dependent and Caspase-independent Apoptotic Cell Death via the Calpain/Bax Protein Signaling Pathway

(2012) Je-Ok Yoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

(2012) C. Kondapalli et al.   Open Biology

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Formation of parkin aggregates and enhanced PINK1 accumulation during the pathogenesis of Parkinson’s disease

(2010) Ji Won Um et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of Transglutaminase in theDrosophilaWing Imaginal Disc Induced an Extra Wing Crossvein Phenotype

(2010) Akira ICHIKAWA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype

(2010) Masaru Umehara et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protein Crosslinking by Transglutaminase Controls Cuticle Morphogenesis in Drosophila

(2010) Toshio Shibata et al.   PLoS One

Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation

(2010) Thung S. Lai et al.   PROTEIN SCIENCE

The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis

(2009) W Malorni et al.   CELL DEATH AND DIFFERENTIATION

Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stress

(2009) Eui Man Jeong et al.   FEBS LETTERS

Transglutaminase-mediated Intramolecular Cross-linking of Membrane-bound α-Synuclein Promotes Amyloid Formation in Lewy Bodies

(2009) Zoltán Nemes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular interaction between parkin and PINK1 in mammalian neuronal cells

(2009) Ji Won Um et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

(2009) C. Vives-Bauza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications

(2008) R. J. Collighan et al.   AMINO ACIDS

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

(2008) A. J. Whitworth et al.   Disease Models & Mechanisms

Parkinson’s disease: A genetic perspective

(2008) Andrea C. Belin et al.   FEBS Journal

The kinase domain of mitochondrial PINK1 faces the cytoplasm

(2008) C. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA