α-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering β-arrestin2-TAB1 interaction in astrocytes

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes

(2018) Okiru Komine et al.   CELL DEATH AND DIFFERENTIATION

Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease

(2018) Abeje Ambaw et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Heat shock protein 70 suppresses neuroinflammation induced by α-synuclein in astrocytes

(2018) Wen-Wen Yu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo

(2018) Ann Kristin Frøyset et al.   Redox Biology

Pramipexole reduces inflammation in the experimental animal models of inflammation

(2017) Heibatollah Sadeghi et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

α-Synuclein-carrying extracellular vesicles in Parkinson’s disease: deadly transmitters

(2016) Dimitry A. Chistiakov et al.   ACTA NEUROLOGICA BELGICA

Parkinson's disease: Autoimmunity and neuroinflammation

(2016) Armando De Virgilio et al.   AUTOIMMUNITY REVIEWS

The β-Arrestins: Multifunctional Regulators of G Protein-coupled Receptors

(2016) Jeffrey S. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic approaches in Parkinson's disease and related disorders

(2016) Elvira Valera et al.   JOURNAL OF NEUROCHEMISTRY

Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice

(2016) Vicente Lieberknecht et al.   MOLECULAR NEUROBIOLOGY

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease

(2016) Yan Zhou et al.   Molecular Neurodegeneration

Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients

(2016) Marios Politis et al.   MOVEMENT DISORDERS

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

Immunomodulatory Effects Mediated by Dopamine

(2016) Rodrigo Arreola et al.   Journal of Immunology Research

Abrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway

(2016) Nan-lin Xiang et al.   Scientific Reports

Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease

(2015) Ganna Tolstanova et al.   DIGESTIVE DISEASES AND SCIENCES

MicroRNA-7 Enhances Subventricular Zone Neurogenesis by Inhibiting NLRP3/Caspase-1 Axis in Adult Neural Stem Cells

(2015) Zheng Fan et al.   MOLECULAR NEUROBIOLOGY

Dopamine Receptors and Neurodegeneration

(2015) Claudia Rangel-Barajas et al.   Aging and Disease

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity

(2015) Sean M. Peterson et al.   PLoS One

β-arrestin protects neurons by mediating endogenous opioid arrest of inflammatory microglia

(2013) X Feng et al.   CELL DEATH AND DIFFERENTIATION

Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

(2013) Yiqing Yan et al.   IMMUNITY

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

(2012) Isabel Lastres-Becker et al.   HUMAN MOLECULAR GENETICS

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

An ADIOL-ERβ-CtBP Transrepression Pathway Negatively Regulates Microglia-Mediated Inflammation

(2011) Kaoru Saijo et al.   CELL

β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway

(2011) Li Qian et al.   JOURNAL OF IMMUNOLOGY

Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

(2010) Xing-Long Gu et al.   Molecular Brain

Fenoterol, a β2-adrenoceptor agonist, inhibits LPS-induced membrane-bound CD14, TLR4/CD14 complex and inflammatory cytokines production through β-arrestin-2 in THP-1 cell line

(2009) Wei Wang et al.   ACTA PHARMACOLOGICA SINICA

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

KATP channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production

(2009) Juan Xie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Toll-like receptors differentially regulate GPCR kinases and arrestins in primary macrophages

(2008) Katie Loniewski et al.   MOLECULAR IMMUNOLOGY