Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes

The immune inhibitory complex CD200/CD200R is developmentally regulated in the mouse brain

(2012) Kalpana Shrivastava et al.   JOURNAL OF COMPARATIVE NEUROLOGY

C3-dependent mechanism of microglial priming relevant to multiple sclerosis

(2012) V. Ramaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD200 fusion protein decreases microglial activation in the hippocampus of aged rats

(2011) F. Fionnuala Cox et al.   BRAIN BEHAVIOR AND IMMUNITY

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

(2011) Adam D. Hart et al.   BRAIN BEHAVIOR AND IMMUNITY

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Gene Expression Profiling Identifies Key Estradiol Targets in the Frontal Cortex of the Rat

(2010) Miklós Sárvári et al.   ENDOCRINOLOGY

Production of Proinflammatory Cytokines and Chemokines During Neuroinflammation: Novel Roles for Estrogen Receptors α and β

(2010) Candice M. Brown et al.   ENDOCRINOLOGY

Estradiol Replacement Alters Expression of Genes Related to Neurotransmission and Immune Surveillance in the Frontal Cortex of Middle-Aged, Ovariectomized Rats

(2010) Miklós Sárvári et al.   ENDOCRINOLOGY

Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System

(2010) R. Khorooshi et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

(2010) eMalick G. Njie et al.   NEUROBIOLOGY OF AGING

17β-estradiol attenuates injury-induced microglia activation in the oculomotor nucleus

(2010) A. Gyenes et al.   NEUROSCIENCE

Actions of estrogens on glial cells: Implications for neuroprotection

(2009) María-Angeles Arevalo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Selective Estrogen Receptor Modulators Decrease Reactive Astrogliosis in the Injured Brain: Effects of Aging and Prolonged Depletion of Ovarian Hormones

(2009) George Barreto et al.   ENDOCRINOLOGY

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

Neuronal regulation of immune responses in the central nervous system

(2009) Li Tian et al.   TRENDS IN IMMUNOLOGY

Steroid hormone receptor expression and function in microglia

(2008) Amanda Sierra et al.   GLIA

Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs

(2008) Silvia Tapia-Gonzalez et al.   JOURNAL OF ENDOCRINOLOGY

Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system

(2008) Ryan N. Dilger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats

(2008) Danielle K. Lewis et al.   JOURNAL OF NEUROIMMUNOLOGY

Complement C3 Deficiency Leads to Accelerated Amyloid   Plaque Deposition and Neurodegeneration and Modulation of the Microglia/Macrophage Phenotype in Amyloid Precursor Protein Transgenic Mice

(2008) M. Maier et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Gene expression changes in the course of normal brain aging are sexually dimorphic

(2008) N. C. Berchtold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA