Evidence for a Dysregulated Immune System in the Etiology of Psychiatric Disorders

CYTOKINE TARGETS IN THE BRAIN: IMPACT ON NEUROTRANSMITTERS AND NEUROCIRCUITS

(2013) Andrew H. Miller et al.   DEPRESSION AND ANXIETY

Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction

(2012) Marni N. Silverman et al.   Annals of the New York Academy of Sciences

Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry

(2012) Sanne A A van Dartel et al.   ANNALS OF THE RHEUMATIC DISEASES

Maternal Autoantibodies in Autism

(2012) Daniel Braunschweig et al.   ARCHIVES OF NEUROLOGY

Long-term anti-TNF therapy and the risk of serious infections in a cohort of patients with rheumatoid arthritis: Comparison of adalimumab, etanercept and infliximab in the GISEA registry

(2012) Fabiola Atzeni et al.   AUTOIMMUNITY REVIEWS

Effect of the Interleukin-1β Gene on Dorsolateral Prefrontal Cortex Function in Schizophrenia: A Genetic Neuroimaging Study

(2012) Mar Fatjó-Vilas et al.   BIOLOGICAL PSYCHIATRY

Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia

(2012)   BIOLOGICAL PSYCHIATRY

Depression and anxiety in patients with rheumatoid arthritis: prevalence rates based on a comparison of the Depression, Anxiety and Stress Scale (DASS) and the hospital, Anxiety and Depression Scale (HADS)

(2012) Tanya Covic et al.   BMC Psychiatry

Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions

(2012) Glaucia Vilar-Pereira et al.   BRAIN BEHAVIOR AND IMMUNITY

Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation

(2012) Martina M. Hughes et al.   BRAIN BEHAVIOR AND IMMUNITY

Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: Further evidence for disease course-related immune alterations?

(2012) Stefan Busse et al.   BRAIN BEHAVIOR AND IMMUNITY

Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism

(2012) Natalia V. Malkova et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation and symptoms of depression and anxiety in patients with acute coronary heart disease

(2012) Andrew Steptoe et al.   BRAIN BEHAVIOR AND IMMUNITY

Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX3CR1)-deficient mice

(2012) Angela W. Corona et al.   BRAIN BEHAVIOR AND IMMUNITY

Central administration of murine interferon-α induces depressive-like behavioral, brain cytokine and neurochemical alterations in mice: A mini-review and original experiments

(2012) Shawn Hayley et al.   BRAIN BEHAVIOR AND IMMUNITY

Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression

(2012) Sinead M. Gibney et al.   BRAIN BEHAVIOR AND IMMUNITY

Abnormal microglial–neuronal spatial organization in the dorsolateral prefrontal cortex in autism

(2012) John T. Morgan et al.   BRAIN RESEARCH

Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge

(2012) Alexander Salazar et al.   HORMONES AND BEHAVIOR

Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study

(2012) Seyed-Hesameddin Abbasi et al.   JOURNAL OF AFFECTIVE DISORDERS

Interferon-Induced Depression in Chronic Hepatitis C

(2012) Marc Udina et al.   JOURNAL OF CLINICAL PSYCHIATRY

The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

(2012) Wouter Beumer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammation in Patients with Schizophrenia: The Therapeutic Benefits of Risperidone Plus Add-On Dextromethorphan

(2012) Shiou-Lan Chen et al.   Journal of Neuroimmune Pharmacology

Immunological characterization and transcription profiling of peripheral blood (PB) monocytes in children with autism spectrum disorders (ASD) and specific polysaccharide antibody deficiency (SPAD): case study

(2012) Harumi Jyonouchi et al.   Journal of Neuroinflammation

Maternal immune activation by poly(I:C) induces expression of cytokines IL-1β and IL-13, chemokine MCP-1 and colony stimulating factor VEGF in fetal mouse brain

(2012) Géraldine Arrode-Brusés et al.   Journal of Neuroinflammation

Depression: an inflammatory illness?: Figure 1

(2012) Rajeev Krishnadas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats

(2012) R. M. Barrientos et al.   JOURNAL OF NEUROSCIENCE

Increased affective ultrasonic communication during fear learning in adult male rats exposed to maternal immune activation

(2012) Nicole Yee et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Neuropoietic cytokines in normal brain development and neurodevelopmental disorders

(2012) H.B. Stolp   MOLECULAR AND CELLULAR NEUROSCIENCE

Peripheral and central inflammation in autism spectrum disorders

(2012) Amaicha Mara Depino   MOLECULAR AND CELLULAR NEUROSCIENCE

Increased inflammatory markers identified in the dorsolateral prefrontal cortex of individuals with schizophrenia

(2012) S G Fillman et al.   MOLECULAR PSYCHIATRY

Functions of microglia in the central nervous system – beyond the immune response

(2012) Hiroaki Wake et al.   Neuron Glia Biology

Microglia in development: linking brain wiring to brain environment

(2012) Rosa C. Paolicelli et al.   Neuron Glia Biology

A critical review of the mechanism of action for the selective serotonin reuptake inhibitors: Do these drugs possess anti-inflammatory properties and how relevant is this in the treatment of depression?

(2012) Frederick Rohan Walker   NEUROPHARMACOLOGY

5-HT1A receptor and apoptosis contribute to interferon-α-induced “depressive-like” behavior in mice

(2012) Fengfeng Ping et al.   NEUROSCIENCE LETTERS

Fluoxetine and aripiprazole treatment following prenatal immune activation exert longstanding effects on rat locomotor response

(2012) Neil M. Richtand et al.   PHYSIOLOGY & BEHAVIOR

Modeling an autism risk factor in mice leads to permanent immune dysregulation

(2012) E. Y. Hsiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Celecoxib enhances the effect of reboxetine and fluoxetine on cortical noradrenaline and serotonin output in the rat

(2012) Daniella Johansson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Immuno-inflammatory, oxidative and nitrosative stress, and neuroprogressive pathways in the etiology, course and treatment of schizophrenia

(2012) George Anderson et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: Associations and functional implications

(2012) Monojit Debnath et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Impaired monocyte activation in schizophrenia

(2012) Norbert Müller et al.   PSYCHIATRY RESEARCH

Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome

(2012) Wouter Beumer et al.   PSYCHONEUROENDOCRINOLOGY

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Prenatal immune challenge in rats: Altered responses to dopaminergic and glutamatergic agents, prepulse inhibition of acoustic startle, and reduced route-based learning as a function of maternal body weight gain after prenatal exposure to poly IC

(2012) Charles V. Vorhees et al.   SYNAPSE

Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring

(2012) Caroline M Forrest et al.   Molecular Brain

Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia

(2012) Peilin Jia et al.   PLoS Computational Biology

A Randomized Controlled Trial of the Tumor Necrosis Factor Antagonist Infliximab for Treatment-Resistant Depression

(2012) Charles L. Raison et al.   JAMA Psychiatry

Schizophrenia: do all roads lead to dopamine or is this where they start? Evidence from two epidemiologically informed developmental rodent models

(2012) D Eyles et al.   Translational Psychiatry

Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder

(2012) T Frodl et al.   Translational Psychiatry

Gene expression profiles associated with depression in patients with chronic hepatitis C (CH-C)

(2012) Aybike Birerdinc et al.   Brain and Behavior

Celecoxib or Naproxen Treatment Does Not Benefit Depressive Symptoms in Persons Age 70 and Older: Findings From a Randomized Controlled Trial

(2011) Cynthia Fields et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Depressive Symptoms, Health Behaviors, and Subsequent Inflammation in Patients With Coronary Heart Disease: Prospective Findings From the Heart and Soul Study

(2011) Hester E. Duivis et al.   AMERICAN JOURNAL OF PSYCHIATRY

Possible association between Interleukin-1beta gene and schizophrenia in a Japanese population

(2011) Daimei Sasayama et al.   Behavioral and Brain Functions

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment

(2011) Taku Nagai et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioural deficits associated with maternal immune activation in the rat model of schizophrenia

(2011) Amy R. Wolff et al.   BEHAVIOURAL BRAIN RESEARCH

Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression

(2011) Thierno Madjou Bah et al.   BEHAVIOURAL BRAIN RESEARCH

Nurr1 is not essential for the development of prepulse inhibition deficits induced by prenatal immune activation

(2011) Stéphanie Vuillermot et al.   BRAIN BEHAVIOR AND IMMUNITY

TREM-1 and DAP12 expression in monocytes of patients with severe psychiatric disorders. EGR3, ATF3 and PU.1 as important transcription factors

(2011) Karin Weigelt et al.   BRAIN BEHAVIOR AND IMMUNITY

Amniotic fluid chemokines and autism spectrum disorders: An exploratory study utilizing a Danish Historic Birth Cohort

(2011) Morsi W. Abdallah et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of risperidone treatment in adolescence on hippocampal neurogenesis, parvalbumin expression, and vascularization following prenatal immune activation in rats

(2011) Yael Piontkewitz et al.   BRAIN BEHAVIOR AND IMMUNITY

Maternal infection and autism

(2011) Paul H. Patterson   BRAIN BEHAVIOR AND IMMUNITY

Evidence that Microglia Mediate the Neurobiological Effects of Chronic Psychological Stress on the Medial Prefrontal Cortex

(2011) M. Hinwood et al.   CEREBRAL CORTEX

Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research

(2011) Anna Meijer et al.   GENERAL HOSPITAL PSYCHIATRY

An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro- and anti-inflammatory forces

(2011) Roosmarijn C. Drexhage et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Elevated macrophage migration inhibitory factor and decreased transforming growth factor-beta levels in major depression — No influence of celecoxib treatment

(2011) R. Musil et al.   JOURNAL OF AFFECTIVE DISORDERS

Cognitive/affective and somatic/affective symptom dimensions of depression are associated with current and future inflammation in heart failure patients

(2011) Nina Kupper et al.   JOURNAL OF AFFECTIVE DISORDERS

Nonsteroidal Anti-Inflammatory Drugs in Schizophrenia

(2011) Iris E. Sommer et al.   JOURNAL OF CLINICAL PSYCHIATRY

Effect of pegylated interferon-α-2a treatment on mental health during recent hepatitis C virus infection

(2011) Maryam Alavi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal  -Catenin Pathway Function in an Alzheimer's Disease Model

(2011) M. Kitazawa et al.   JOURNAL OF IMMUNOLOGY

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

(2011) Peilin Jia et al.   JOURNAL OF MEDICAL GENETICS

Effects of risperidone and paliperidone pre-treatment on locomotor response following prenatal immune activation

(2011) Neil M. Richtand et al.   JOURNAL OF PSYCHIATRIC RESEARCH

To poly(I:C) or not to poly(I:C): Advancing preclinical schizophrenia research through the use of prenatal immune activation models

(2011) Urs Meyer et al.   NEUROPHARMACOLOGY

Towards a glutamate hypothesis of depression

(2011) Gerard Sanacora et al.   NEUROPHARMACOLOGY

Depressive-like behavior induced by tumor necrosis factor-α in mice

(2011) Manuella P. Kaster et al.   NEUROPHARMACOLOGY

The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis

(2011) Jonas Hannestad et al.   NEUROPSYCHOPHARMACOLOGY

Effect of paliperidone and risperidone on extracellular glutamate in the prefrontal cortex of rats exposed to prenatal immune activation or MK-801

(2011) Nicole L. Roenker et al.   NEUROSCIENCE LETTERS

Schizophrenia and Autism: Both Shared and Disorder-Specific Pathogenesis Via Perinatal Inflammation?

(2011) URS MEYER et al.   PEDIATRIC RESEARCH

Minocycline produced antidepressant-like effects on the learned helplessness rats with alterations in levels of monoamine in the amygdala and no changes in BDNF levels in the hippocampus at baseline

(2011) Shiho Arakawa et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

In Search of Cellular Immunophenotypes in the Blood of Children with Autism

(2011) Paul Ashwood et al.   PLoS One

Expression Profiling of Autism Candidate Genes during Human Brain Development Implicates Central Immune Signaling Pathways

(2011) Mark N. Ziats et al.   PLoS One

Dose-Dependent Effects of Endotoxin on Neurobehavioral Functions in Humans

(2011) Jan-Sebastian Grigoleit et al.   PLoS One

Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans

(2011) J. L. Warner-Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adjunct minocycline to clozapine treated patients with persistent schizophrenia symptoms

(2011) Deanna L. Kelly et al.   SCHIZOPHRENIA RESEARCH

Is Depression an Inflammatory Disorder?

(2011) Charles L. Raison et al.   Current Psychiatry Reports

Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies

(2010) Alan S. Brown et al.   AMERICAN JOURNAL OF PSYCHIATRY

Prenatal Interaction of Mutant DISC1 and Immune Activation Produces Adult Psychopathology

(2010) Bagrat Abazyan et al.   BIOLOGICAL PSYCHIATRY

Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism

(2010) John T. Morgan et al.   BIOLOGICAL PSYCHIATRY

Autoimmune diseases, bipolar disorder, and non-affective psychosis

(2010) William W Eaton et al.   BIPOLAR DISORDERS

Prenatal inflammation impairs adult neurogenesis and memory related behavior through persistent hippocampal TGFβ1 downregulation

(2010) Mariana Graciarena et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of prenatal infection on brain development and behavior: A review of findings from animal models

(2010) Patricia Boksa   BRAIN BEHAVIOR AND IMMUNITY

Altered T cell responses in children with autism

(2010) Paul Ashwood et al.   BRAIN BEHAVIOR AND IMMUNITY

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

(2010) Paul Ashwood et al.   BRAIN BEHAVIOR AND IMMUNITY

REVIEW: Genome-Wide Findings in Schizophrenia and the Role of Gene-Environment Interplay

(2010) Ruud Van Winkel et al.   CNS Neuroscience & Therapeutics

Association between tendency towards depression and severity of rheumatoid arthritis from a national representative sample: the Medical Expenditure Panel Survey

(2010) Deepali Godha et al.   CURRENT MEDICAL RESEARCH AND OPINION

Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patients

(2010) Roosmarijn C. Drexhage et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Electroconvulsive therapy has acute immunological and neuroendocrine effects in patients with major depressive disorder

(2010) Sjoerd B.A.H.A. Fluitman et al.   JOURNAL OF AFFECTIVE DISORDERS

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

(2010) Xin Fu et al.   Journal of Neuroinflammation

Regulatory T cells increased while IL-1β decreased during antidepressant therapy

(2010) Hubertus Himmerich et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Voxel-based analysis of postnatal white matter microstructure in mice exposed to immune challenge in early or late pregnancy

(2010) Qi Li et al.   NEUROIMAGE

Late Prenatal Immune Activation in Mice Leads to Behavioral and Neurochemical Abnormalities Relevant to the Negative Symptoms of Schizophrenia

(2010) Byron KY Bitanihirwe et al.   NEUROPSYCHOPHARMACOLOGY

Prenatal exposure to lipopolysaccharide results in cognitive deficits in age-increasing offspring rats

(2010) L.Y. Hao et al.   NEUROSCIENCE

Glucocorticoids, cytokines and brain abnormalities in depression

(2010) Patricia A. Zunszain et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Cytokines mediated inflammation and decreased neurogenesis in animal models of depression

(2010) Cai Song et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

(2010) Marta Kubera et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The environment and susceptibility to schizophrenia

(2010) Alan S. Brown   PROGRESS IN NEUROBIOLOGY

Tyrosine hydroxylase, interleukin-1β and tumor necrosis factor-α are overexpressed in peripheral blood mononuclear cells from schizophrenia patients as determined by semi-quantitative analysis

(2010) Liang Liu et al.   PSYCHIATRY RESEARCH

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Infliximab, a TNF-alpha antagonist treatment in patients with ankylosing spondylitis: the impact on depression, anxiety and quality of life level

(2010) I. Ertenli et al.   RHEUMATOLOGY INTERNATIONAL

Risperidone Administered During Asymptomatic Period of Adolescence Prevents the Emergence of Brain Structural Pathology and Behavioral Abnormalities in an Animal Model of Schizophrenia

(2010) Y. Piontkewitz et al.   SCHIZOPHRENIA BULLETIN

Celecoxib treatment in an early stage of schizophrenia: Results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment

(2010) Norbert Müller et al.   SCHIZOPHRENIA RESEARCH

A Danish National Birth Cohort study of maternal HSV-2 antibodies as a risk factor for schizophrenia in their offspring

(2010) Preben B. Mortensen et al.   SCHIZOPHRENIA RESEARCH

Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8

(2010) Lauren M. Ellman et al.   SCHIZOPHRENIA RESEARCH

Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

(2009) Daisuke Ibi et al.   BEHAVIOURAL BRAIN RESEARCH

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Differential monocyte responses to TLR ligands in children with autism spectrum disorders

(2009) Amanda M. Enstrom et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like Receptors in Pregnancy Disorders and Placental Dysfunction

(2009) Joan K. Riley et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Fetal Infections and Brain Development

(2009) James F. Bale   CLINICS IN PERINATOLOGY

Clinical trial of adjunctive celecoxib treatment in patients with major depression: a double blind and placebo controlled trial

(2009) Shahin Akhondzadeh et al.   DEPRESSION AND ANXIETY

Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain

(2009) Jian-You Guo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction between environmental and genetic factors modulates schizophrenic endophenotypes in the Snap-25 mouse mutant blind-drunk

(2009) Peter L. Oliver et al.   HUMAN MOLECULAR GENETICS

A Double-Blind, Randomized Study of Minocycline for the Treatment of Negative and Cognitive Symptoms in Early-Phase Schizophrenia

(2009) Yechiel Levkovitz et al.   JOURNAL OF CLINICAL PSYCHIATRY

Increase in Plasma Proinflammatory Cytokines After Electroconvulsive Therapy in Patients With Depressive Disorder

(2009) Kai Lehtimäki et al.   JOURNAL OF ECT

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Elevated immune response in the brain of autistic patients

(2009) Xiaohong Li et al.   JOURNAL OF NEUROIMMUNOLOGY

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

Schizophrenia

(2009) Jim van Os et al.   LANCET

MHC Class I: An Unexpected Role in Neuronal Plasticity

(2009) Carla J. Shatz   NEURON

Prenatal Immune Challenge Is an Environmental Risk Factor for Brain and Behavior Change Relevant to Schizophrenia: Evidence from MRI in a Mouse Model

(2009) Qi Li et al.   PLoS One

Prenatal exposure to infection: a primary mechanism for abnormal dopaminergic development in schizophrenia

(2009) Urs Meyer et al.   PSYCHOPHARMACOLOGY

Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics

(2009) Xiang Yang Zhang et al.   PSYCHOPHARMACOLOGY

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

Schizophrenia and 1957 Pandemic of Influenza: Meta-analysis

(2009) J.-P. Selten et al.   SCHIZOPHRENIA BULLETIN

Immune involvement in schizophrenia and autism: Etiology, pathology and animal models

(2008) Paul H. Patterson   BEHAVIOURAL BRAIN RESEARCH

Activation of the maternal immune system alters cerebellar development in the offspring

(2008) Limin Shi et al.   BRAIN BEHAVIOR AND IMMUNITY

Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection

(2008) Ruth M. Barrientos et al.   BRAIN BEHAVIOR AND IMMUNITY

Infliximab improves health-related quality of life in the presence of comorbidities among patients with moderate-to-severe psoriasis

(2008) S.R. Feldman et al.   BRITISH JOURNAL OF DERMATOLOGY

Minocycline as Adjunctive Therapy for Schizophrenia

(2008) Tsuyoshi Miyaoka et al.   CLINICAL NEUROPHARMACOLOGY

Impact du traitement par interféron α sur le métabolisme du tryptophane chez des patients porteurs d’hépatite C chronique

(2008) J. Vignau et al.   ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE

Dopamine and serotonin levels following prenatal viral infection in mouse—Implications for psychiatric disorders such as schizophrenia and autism

(2008) Christine Winter et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration

(2008) Caroline André et al.   JOURNAL OF NEUROIMMUNOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Autism: Definition, Neurobiology, Screening, Diagnosis

(2008) Isabelle Rapin et al.   PEDIATRIC CLINICS OF NORTH AMERICA

The Association of Depressive Symptoms with Inflammatory Factors and Adipokines in Middle-Aged and Older Chinese

(2008) An Pan et al.   PLoS One

Minocycline, schizophrenia and GluR1 glutamate receptors

(2008) Radmila Manev et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Influence of continuous infusion of interleukin-1β on depression-related processes in mice: corticosterone, circulating cytokines, brain monoamines, and cytokine mRNA expression

(2008) Hymie Anisman et al.   PSYCHOPHARMACOLOGY

Evaluating Early Preventive Antipsychotic and Antidepressant Drug Treatment in an Infection-Based Neurodevelopmental Mouse Model of Schizophrenia

(2008) U. Meyer et al.   SCHIZOPHRENIA BULLETIN

A Review of the Fetal Brain Cytokine Imbalance Hypothesis of Schizophrenia

(2008) U. Meyer et al.   SCHIZOPHRENIA BULLETIN

Patients with schizophrenia show raised serum levels of the pro-inflammatory chemokine CCL2: Association with the metabolic syndrome in patients?

(2008) R DREXHAGE et al.   SCHIZOPHRENIA RESEARCH

Maternal infection leads to abnormal gene regulation and brain atrophy in mouse offspring: Implications for genesis of neurodevelopmental disorders

(2008) S. Hossein Fatemi et al.   SCHIZOPHRENIA RESEARCH

Maternal Exposure to Herpes Simplex Virus and Risk of Psychosis Among Adult Offspring

(2007) Stephen L. Buka et al.   BIOLOGICAL PSYCHIATRY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE

Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1β and tumor necrosis factor-α

(2007) Jennifer M. Loftis et al.   NEUROSCIENCE LETTERS

Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia and depression is associated with suicide

(2006) Johann Steiner et al.   JOURNAL OF PSYCHIATRIC RESEARCH