Critical role for the AIM2 inflammasome during acute CNS bacterial infection

NLRP3 and ASC Differentially Affect the Lung Transcriptome during Pneumococcal Pneumonia

(2013) Miriam H. van Lieshout et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The AIM2 Inflammasome Is Involved in Macrophage Activation During Infection With Virulent Mycobacterium bovis Strain

(2013) Yang Yang et al.   JOURNAL OF INFECTIOUS DISEASES

IL-1RI (Interleukin-1 Receptor Type I) Signalling is Essential for Host Defence and Hemichannel Activity During Acute Central Nervous System Bacterial Infection

(2012) Juan Xiong et al.   ASN Neuro

AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages

(2012) R Pierini et al.   CELL DEATH AND DIFFERENTIATION

Microglia are required for astroglial toll-like receptor 4 response and for optimal TLR2 and TLR3 response

(2012) Thomas H. Holm et al.   GLIA

Increasing Burden of Methicillin-Resistant Staphylococcus aureus Hospitalizations at US Academic Medical Centers, 2003–2008

(2012) Michael Z. David et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Multiple Brain Abscesses in a Neonate after Blood Stream Infection with Methicillin-Resistant Staphylococcus aureus

(2012) Prem Arora et al.   JOURNAL OF PEDIATRICS

Sterile hemorrhagic brain abscess in infective endocarditis

(2012) Bharat Guthikonda et al.   NEUROLOGY INDIA

IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection

(2012) Hilario J. Ramos et al.   PLoS Pathogens

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release

(2011) Tobias Hoegen et al.   JOURNAL OF IMMUNOLOGY

Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia

(2011) Richa Hanamsagar et al.   JOURNAL OF NEUROCHEMISTRY

The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes

(2011) Rebecca C. Coll et al.   PLoS One

Streptococcus sanguinis Brain Abscess as Complication of Subclinical Endocarditis: Emphasizing the Importance of Prompt Diagnosis

(2011) Hayah Kassis et al.   SOUTHERN MEDICAL JOURNAL

Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome

(2010) Sarah Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

(2010) Jianghong Wu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: NLRC5-Dependent Activation of the Inflammasome

(2010) B. K. Davis et al.   JOURNAL OF IMMUNOLOGY

Differential Regulation of Caspase-1 Activation via NLRP3/NLRC4 Inflammasomes Mediated by Aerolysin and Type III Secretion System during Aeromonas veronii Infection

(2010) A. J. McCoy et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis

(2010) P. J. Shaw et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Cytosolic Bacterial DNA Activates the Inflammasome via Aim2

(2010) S. E. Warren et al.   JOURNAL OF IMMUNOLOGY

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

(2010) D. Gris et al.   JOURNAL OF IMMUNOLOGY

Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia

(2010) M. Lamkanfi et al.   JOURNAL OF IMMUNOLOGY

The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18

(2010) S. Jha et al.   JOURNAL OF NEUROSCIENCE

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Brain abscess: An overview

(2010) Dattatraya Muzumdar et al.   International Journal of Surgery

MyD88 Expression by CNS-Resident Cells is Pivotal for Eliciting Protective Immunity in Brain Abscesses

(2009) Sarita Garg et al.   ASN Neuro

Involvement of cathepsin B in the processing and secretion of interleukin-1β in chromogranin A-stimulated microglia

(2009) Kayo Terada et al.   GLIA

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

Central nervous system invasion by community-acquired meticillin-resistant Staphylococcus aureus

(2009) R. Naesens et al.   JOURNAL OF MEDICAL MICROBIOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

(2009) Robin R. Craven et al.   PLoS One