The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain

Altered Levels of Amyloid Precursor Protein Intracellular Domain-interacting Proteins in Alzheimer Disease

(2013) Arunabha Chakrabarti et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

(2013) Nathalie Pierrot et al.   EMBO Molecular Medicine

The amyloid precursor protein: A biochemical enigma in brain development, function and disease

(2013) Natalia N. Nalivaeva et al.   FEBS LETTERS

The Amyloid Precursor Protein Represses Expression of Acetylcholinesterase in Neuronal Cell Lines

(2013) David A. Hicks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

From synaptic spines to nuclear signaling: nuclear and synaptic actions of the amyloid precursor protein

(2013) Jean-Noël Octave et al.   JOURNAL OF NEUROCHEMISTRY

Proteolytic Degradation of Amyloid  -Protein

(2013) T. Saido et al.   Cold Spring Harbor Perspectives in Medicine

The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth

(2012) Fangfang Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model

(2012) J. Brouillette et al.   JOURNAL OF NEUROSCIENCE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism

(2012) Marcus O. W. Grimm et al.   PLoS One

Identification of beta-amyloid-binding sites on transthyretin

(2012) J. Du et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Preventing Alzheimer's Disease

(2012) D. J. Selkoe   SCIENCE

Nuclear signalling by membrane protein intracellular domains: The AICD enigma

(2011) Caroline Beckett et al.   CELLULAR SIGNALLING

The AICD Interacting Protein DAB1 is Up-Regulated in Alzheimer Frontal Cortex Brain Samples and Causes Deregulation of Proteins Involved in Gene Expression Changes

(2011) T. Muller et al.   Current Alzheimer Research

An alternative metabolic pathway of amyloid precursor protein C-terminal fragments via cathepsin B in a human neuroglioma model

(2011) Masashi Asai et al.   FASEB JOURNAL

The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells

(2011) Yue Hong et al.   INTERNATIONAL JOURNAL OF CANCER

Effect of Sodium Valproate Administration on Brain Neprilysin Expression and Memory in Rats

(2011) Natalia N. Nalivaeva et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The physiology of the β-amyloid precursor protein intracellular domain AICD

(2011) Raphaëlle Pardossi-Piquard et al.   JOURNAL OF NEUROCHEMISTRY

Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer’s disease?

(2011) Natalia N. Nalivaeva et al.   JOURNAL OF NEUROCHEMISTRY

Twenty years of Alzheimer’s disease-causing mutations

(2011) Alison Goate et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal Production of Transthyretin in Human and Murine Alzheimer's Disease: Is It Protective?

(2011) X. Li et al.   JOURNAL OF NEUROSCIENCE

A Weak Base-Generating System Suitable for Selective Manipulation of Lysosomal pH

(2011) Luciene R. Carraro-Lacroix et al.   TRAFFIC

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

(2010) Heather R. Pelzel et al.   BMC NEUROSCIENCE

The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway

(2010) Nikolai D. Belyaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

(2010) S. W. Pimplikar et al.   JOURNAL OF NEUROSCIENCE

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation

(2010) O. M. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein

(2009) Sandra Huysseune et al.   FASEB JOURNAL

c-Abl modulates AICD dependent cellular responses: Transcriptional induction and apoptosis

(2009) Mary C. Vázquez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

(2009) K. Ghosal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

(2008) Nikolai D Belyaev et al.   EMBO REPORTS

The AβCs of Aβ-cleaving Proteases

(2008) Malcolm A. Leissring   JOURNAL OF BIOLOGICAL CHEMISTRY

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A  toxicity

(2008) J. N. Buxbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA