An alternative metabolic pathway of amyloid precursor protein C-terminal fragments via cathepsin B in a human neuroglioma model

Cathepsin B Is Involved in the Trafficking of TNF- -Containing Vesicles to the Plasma Membrane in Macrophages

(2014) S.-D. Ha et al.   JOURNAL OF IMMUNOLOGY

Efficient four-drug cocktail therapy targeting amyloid-β peptide for Alzheimer's disease

(2010) Masashi Asai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Alzheimer's disease: strategies for disease modification

(2010) Martin Citron   NATURE REVIEWS DRUG DISCOVERY

Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein

(2009) Vivian Y.H. Hook et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

(2009) Kristin T. Jacobsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Disease-Modifying Approach to the Treatment of Alzheimerʼs Disease

(2009) Francesco Panza et al.   DRUGS & AGING

Secretase inhibitors and modulators for Alzheimer’s disease treatment

(2009) Taisuke Tomita   Expert Review of Neurotherapeutics

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

(2009) K. Ghosal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Amyloid β-Protein Precursor by Phosphorylation and Protein Interactions

(2008) Toshiharu Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein

(2008) Vivian Y. H. Hook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cathepsins B and L Differentially Regulate Amyloid Precursor Protein Processing

(2008) D. M. Klein et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON

Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders

(2007) Neville Marks et al.   NEUROCHEMISTRY INTERNATIONAL

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

(2003) H. F. Dovey et al.   JOURNAL OF NEUROCHEMISTRY