MS-275, a Class I histone deacetylase inhibitor, protects the p53-deficient mouse against ischemic injury

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

(2013) Benjamin E. L. Lauffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic Mechanisms in Cerebral Ischemia

(2013) Sophie Schweizer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Specific Acetylation of p53 by HDAC Inhibition Prevents DNA Damage-Induced Apoptosis in Neurons

(2013) C. Brochier et al.   JOURNAL OF NEUROSCIENCE

Disassociation of Histone Deacetylase-3 from Normal Huntingtin Underlies Mutant Huntingtin Neurotoxicity

(2013) F. H. Bardai et al.   JOURNAL OF NEUROSCIENCE

Novel Protective Effects of Histone Deacetylase Inhibition on Stroke and White Matter Ischemic Injury

(2013) Selva Baltan et al.   Neurotherapeutics

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

Histone deacetylase inhibitors preserve function in aging axons

(2012) Selva Baltan   JOURNAL OF NEUROCHEMISTRY

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage

(2011) Bing Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Transcription factor p53 influences microglial activation phenotype

(2011) Suman Jayadev et al.   GLIA

Histone Deacetylase Inhibitors Preserve White Matter Structure and Function during Ischemia by Conserving ATP and Reducing Excitotoxicity

(2011) S. Baltan et al.   JOURNAL OF NEUROSCIENCE

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Epigenetics: an Expanding New Piece of the Stroke Puzzle

(2011) William J. Pearce   Translational Stroke Research

Expression of Histone Deacetylases in Cellular Compartments of the Mouse Brain and the Effects of Ischemia

(2011) Selva Baltan et al.   Translational Stroke Research

Emerging Role of Epigenetics in Stroke

(2010) Irfan A. Qureshi et al.   ARCHIVES OF NEUROLOGY

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates

(2010) Ya-Li Yao et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies

(2010) Claire L. Gibson et al.   JOURNAL OF NEUROCHEMISTRY

NRF2, cancer and calorie restriction

(2010) A Martín-Montalvo et al.   ONCOGENE

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

(2009) Tae Gen Son et al.   JOURNAL OF NEUROCHEMISTRY

Histone Deacetylase Inhibitors Prevent p53-Dependent and p53-Independent Bax-Mediated Neuronal Apoptosis through Two Distinct Mechanisms

(2009) T. Uo et al.   JOURNAL OF NEUROSCIENCE

Focal Nature of Neurological Disorders Necessitates Isotype-Selective Histone Deacetylase (HDAC) Inhibitors

(2009) Elizabeth A. Thomas   MOLECULAR NEUROBIOLOGY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

(2009) R. L. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Histone Deacetylases as a Multifaceted Approach to Treat the Diverse Outcomes of Stroke

(2009) Brett Langley et al.   STROKE

Epigenetics: molecular mechanisms and implications for disease

(2009) Adam E. Handel et al.   TRENDS IN MOLECULAR MEDICINE

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

HDAC2: a critical factor in health and disease

(2009) Oliver H. Krämer   TRENDS IN PHARMACOLOGICAL SCIENCES

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL

Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21waf1/cip1 in Cell Cycle-Independent Neuroprotection

(2008) B. Langley et al.   JOURNAL OF NEUROSCIENCE

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS

Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity

(2008) Dohoon Kim et al.   NEURON

Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells

(2007) Glen W. Humphrey et al.   DIFFERENTIATION