Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

Mechanisms and assessment of statin-related muscular adverse effects

(2014) Dirk Moßhammer et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

(2013) K L R Brouwer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The SLC22 family with transporters of organic cations, anions and zwitterions

(2013) Hermann Koepsell   MOLECULAR ASPECTS OF MEDICINE

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

(2013) Anne T Nies et al.   Genome Medicine

Clinical significance of organic anion transporting polypeptides (OATPs) in drug disposition: their roles in hepatic clearance and intestinal absorption

(2012) Yoshihisa Shitara et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

(2012) Alice Kiselyuk et al.   CHEMISTRY & BIOLOGY

The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

(2012) R A Wilke et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors

(2012) Bin Fang et al.   NUCLEIC ACIDS RESEARCH

Drug transport by Organic Anion Transporters (OATs)

(2012) Gerhard Burckhardt   PHARMACOLOGY & THERAPEUTICS

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Prediction of the Overall Renal Tubular Secretion and Hepatic Clearance of Anionic Drugs and a Renal Drug-Drug Interaction Involving Organic Anion Transporter 3 in Humans by In Vitro Uptake Experiments

(2011) T. Watanabe et al.   DRUG METABOLISM AND DISPOSITION

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

Proton Pump Inhibitors Inhibit Metformin Uptake by Organic Cation Transporters (OCTs)

(2011) Anne T. Nies et al.   PLoS One

HNF4α—role in drug metabolism and potential drug target?

(2010) Wendy W Hwang-Verslues et al.   CURRENT OPINION IN PHARMACOLOGY

The Human Organic Anion Transporter Genes OAT5 and OAT7 Are Transactivated by Hepatocyte Nuclear Factor-1  (HNF-1 )

(2010) K. Klein et al.   MOLECULAR PHARMACOLOGY

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

(2010) Kathrin Klein et al.   Frontiers in Pharmacology

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation

(2009) Stephanie E. Hesselson et al.   PLoS One

Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs

(2008) Anne T Nies et al.   Expert Opinion on Drug Metabolism & Toxicology

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE