Mechanisms and assessment of statin-related muscular adverse effects

Lack of association between SLCO1B1 polymorphisms and clinical myalgia following rosuvastatin therapy

(2013) Jacqueline S. Danik et al.   AMERICAN HEART JOURNAL

Narrative Review: Statin-Related Myopathy

(2013) Tisha R. Joy   ANNALS OF INTERNAL MEDICINE

Statin Toxicity From Macrolide Antibiotic Coprescription

(2013) Amit M. Patel et al.   ANNALS OF INTERNAL MEDICINE

Does Reduced Creatine Synthesis Protect against Statin Myopathy?

(2013) Kevin D. Ballard et al.   Cell Metabolism

SLCO1B1 Genetic Variant Associated With Statin-Induced Myopathy: A Proof-of-Concept Study Using the Clinical Practice Research Datalink

(2013) D F Carr et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A statin-dependent QTL for GATM expression is associated with statin-induced myopathy

(2013) Lara M. Mangravite et al.   NATURE

Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

(2013) Anne T Nies et al.   Genome Medicine

The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

(2012) R A Wilke et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mechanisms of statin-induced myalgia assessed by physiogenomic associations

(2011) Gualberto Ruaño et al.   ATHEROSCLEROSIS

Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes

(2011) Hyo-Bum Kwak et al.   FREE RADICAL BIOLOGY AND MEDICINE

Weighing the Benefits of High-Dose Simvastatin against the Risk of Myopathy

(2011) Amy Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact ofSLCO1B1(OATP1B1) andABCG2(BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins

(2011) Grant T. Generaux et al.   XENOBIOTICA

The relationship of vitamin D deficiency to statin myopathy

(2010) Ankur Gupta et al.   ATHEROSCLEROSIS

Coenzyme Q10 and Statin Myalgia: What is the Evidence?

(2010) Emilie Mas et al.   Current Atherosclerosis Reports

Evidence-Based Management of Statin Myopathy

(2010) Charles R. Harper et al.   Current Atherosclerosis Reports

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial

(2010)   LANCET

Association between statin-associated myopathy and skeletal muscle damage

(2009) M. G. Mohaupt et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Increased Levels of 25 Hydroxyvitamin D and 1,25-Dihydroxyvitamin D After Rosuvastatin Treatment: A Novel Pleiotropic Effect of Statins?

(2009) Bunyamin Yavuz et al.   CARDIOVASCULAR DRUGS AND THERAPY

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

(2009) Michael J. Knauer et al.   CIRCULATION RESEARCH

Transporter Pharmacogenetics and Statin Toxicity

(2009) M Niemi   CLINICAL PHARMACOLOGY & THERAPEUTICS

Statin use and its association with musculoskeletal symptoms--a cross-sectional study in primary care settings

(2009) D. Mosshammer et al.   FAMILY PRACTICE

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect

(2009) Peirang Cao et al.   FASEB JOURNAL

The SLCO1B1*5Genetic Variant Is Associated With Statin-Induced Side Effects

(2009) Deepak Voora et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vitamin D Levels and Lipid Response to Atorvastatin

(2009) José Luis Pérez-Castrillón et al.   International Journal of Endocrinology

Once-a-Week Rosuvastatin (2.5 to 20 mg) in Patients With a Previous Statin Intolerance

(2008) Janelle F. Ruisinger et al.   AMERICAN JOURNAL OF CARDIOLOGY

Contribution of Multidrug Resistance-Associated Protein 2 to Secretory Intestinal Transport of Organic Anions

(2008) Shirou Itagaki et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Vitamin D insufficiency - a novel mechanism of statin-induced myalgia?

(2008) Paul Lee et al.   CLINICAL ENDOCRINOLOGY

Effects of Vitamin D Supplementation in Atorvastatin-Treated Patients: A New Drug Interaction With an Unexpected Consequence

(2008) JB Schwartz   CLINICAL PHARMACOLOGY & THERAPEUTICS

Interplay of conjugating enzymes with OATP uptake transporters and ABCC/MRP efflux pumps in the elimination of drugs

(2008) Anne T Nies et al.   Expert Opinion on Drug Metabolism & Toxicology

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Low serum 25 (OH) vitamin D levels (

(2008) Waqas Ahmed et al.   Translational Research

Efficacy and Tolerability of Fluvastatin XL 80 mg Alone, Ezetimibe Alone, and the Combination of Fluvastatin XL 80 mg With Ezetimibe in Patients With a History of Muscle-Related Side Effects With Other Statins

(2007) Evan A. Stein et al.   AMERICAN JOURNAL OF CARDIOLOGY