A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations

In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities

(2015) Jef Stappaerts et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

(2014) Nicky Thomas et al.   AAPS Journal

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 4: Proposing a New Lipid Formulation Performance Classification System

(2014) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase

(2014) Jean-Claude Bakala-N’Goma et al.   PHARMACEUTICAL RESEARCH

Biopharmaceutical Modeling of Drug Supersaturation During Lipid-Based Formulation Digestion Considering an Absorption Sink

(2014) Cordula Stillhart et al.   PHARMACEUTICAL RESEARCH

Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: Case studies with fenofibrate

(2013) Brendan T. Griffin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The Potential for Drug Supersaturation during Intestinal Processing of Lipid-Based Formulations May Be Enhanced for Basic Drugs

(2013) Yan Yan Yeap et al.   MOLECULAR PHARMACEUTICS

Insights into Drug Precipitation Kinetics during In Vitro Digestion of a Lipid-Based Drug Delivery System Using In-Line Raman Spectroscopy and Mathematical Modeling

(2013) Cordula Stillhart et al.   PHARMACEUTICAL RESEARCH

Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients

(2013) Linda C. Persson et al.   PHARMACEUTICAL RESEARCH

Design of Lipid-Based Formulations for Oral Administration of Poorly Water-Soluble Drug Fenofibrate: Effects of Digestion

(2012) Kazi Mohsin   AAPS PHARMSCITECH

Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

(2012) Jan Bevernage et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Application of Lipid-Based Formulations in Drug Discovery

(2012) Xue-Qing Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

(2012) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid Digestion as a Trigger for Supersaturation: Evaluation of the Impact of Supersaturation Stabilization on the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems

(2012) Mette U. Anby et al.   MOLECULAR PHARMACEUTICS

Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion

(2012) Hywel D. Williams et al.   MOLECULAR PHARMACEUTICS

In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems

(2011) Anne T. Larsen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Application of a Biphasic Test for Characterization of In Vitro Drug Release of Immediate Release Formulations of Celecoxib and Its Relevance to In Vivo Absorption

(2010) Yi Shi et al.   MOLECULAR PHARMACEUTICS

IVIVC in oral absorption for fenofibrate immediate release tablets using a dissolution/permeation system

(2008) Philipp Buch et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Enhancing intestinal drug solubilisation using lipid-based delivery systems

(2007) Christopher J.H. Porter et al.   ADVANCED DRUG DELIVERY REVIEWS

Dissolution enhancement of fenofibrate by micronization, cogrinding and spray-drying: Comparison with commercial preparations

(2007) Markus Vogt et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs

(2007) Jean F. Cuiné et al.   JOURNAL OF PHARMACEUTICAL SCIENCES