A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations
出版年份 2015 全文链接
标题
A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations
作者
关键词
absorption, drug solubilisation, <em class=EmphasisTypeItalic >in situ</em> intestinal perfusion, lipid-based drug delivery systems, supersaturation
出版物
PHARMACEUTICAL RESEARCH
Volume 33, Issue 4, Pages 970-982
出版商
Springer Nature
发表日期
2015-12-25
DOI
10.1007/s11095-015-1843-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities
- (2015) Jef Stappaerts et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate
- (2014) Nicky Thomas et al. AAPS Journal
- Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 4: Proposing a New Lipid Formulation Performance Classification System
- (2014) Hywel D. Williams et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase
- (2014) Jean-Claude Bakala-N’Goma et al. PHARMACEUTICAL RESEARCH
- Biopharmaceutical Modeling of Drug Supersaturation During Lipid-Based Formulation Digestion Considering an Absorption Sink
- (2014) Cordula Stillhart et al. PHARMACEUTICAL RESEARCH
- Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: Case studies with fenofibrate
- (2013) Brendan T. Griffin et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- The Potential for Drug Supersaturation during Intestinal Processing of Lipid-Based Formulations May Be Enhanced for Basic Drugs
- (2013) Yan Yan Yeap et al. MOLECULAR PHARMACEUTICS
- Insights into Drug Precipitation Kinetics during In Vitro Digestion of a Lipid-Based Drug Delivery System Using In-Line Raman Spectroscopy and Mathematical Modeling
- (2013) Cordula Stillhart et al. PHARMACEUTICAL RESEARCH
- Computational Prediction of Drug Solubility in Lipid Based Formulation Excipients
- (2013) Linda C. Persson et al. PHARMACEUTICAL RESEARCH
- Design of Lipid-Based Formulations for Oral Administration of Poorly Water-Soluble Drug Fenofibrate: Effects of Digestion
- (2012) Kazi Mohsin AAPS PHARMSCITECH
- Drug precipitation–permeation interplay: Supersaturation in an absorptive environment
- (2012) Jan Bevernage et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Application of Lipid-Based Formulations in Drug Discovery
- (2012) Xue-Qing Chen et al. JOURNAL OF MEDICINAL CHEMISTRY
- Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations
- (2012) Hywel D. Williams et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Lipid Digestion as a Trigger for Supersaturation: Evaluation of the Impact of Supersaturation Stabilization on the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems
- (2012) Mette U. Anby et al. MOLECULAR PHARMACEUTICS
- Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion
- (2012) Hywel D. Williams et al. MOLECULAR PHARMACEUTICS
- In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems
- (2011) Anne T. Larsen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Application of a Biphasic Test for Characterization of In Vitro Drug Release of Immediate Release Formulations of Celecoxib and Its Relevance to In Vivo Absorption
- (2010) Yi Shi et al. MOLECULAR PHARMACEUTICS
- IVIVC in oral absorption for fenofibrate immediate release tablets using a dissolution/permeation system
- (2008) Philipp Buch et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhancing intestinal drug solubilisation using lipid-based delivery systems
- (2007) Christopher J.H. Porter et al. ADVANCED DRUG DELIVERY REVIEWS
- Dissolution enhancement of fenofibrate by micronization, cogrinding and spray-drying: Comparison with commercial preparations
- (2007) Markus Vogt et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs
- (2007) Jean F. Cuiné et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More