Insights into Drug Precipitation Kinetics during In Vitro Digestion of a Lipid-Based Drug Delivery System Using In-Line Raman Spectroscopy and Mathematical Modeling
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Title
Insights into Drug Precipitation Kinetics during In Vitro Digestion of a Lipid-Based Drug Delivery System Using In-Line Raman Spectroscopy and Mathematical Modeling
Authors
Keywords
<em class=EmphasisTypeItalic >in vitro</em> lipolysis, kinetics of precipitation, lipid-based drug delivery systems, Raman spectroscopy, supersaturation
Journal
PHARMACEUTICAL RESEARCH
Volume 30, Issue 12, Pages 3114-3130
Publisher
Springer Nature
Online
2013-02-28
DOI
10.1007/s11095-013-0999-2
References
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- (2012) Jan Bevernage et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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- (2012) Mette U. Anby et al. MOLECULAR PHARMACEUTICS
- Toward the Establishment of Standardized in Vitro Tests for Lipid-Based Formulations. 2. The Effect of Bile Salt Concentration and Drug Loading on the Performance of Type I, II, IIIA, IIIB, and IV Formulations during in Vitro Digestion
- (2012) Hywel D. Williams et al. MOLECULAR PHARMACEUTICS
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- Advancing in-vitro drug precipitation testing: new process monitoring tools and a kinetic nucleation and growth model
- (2011) Yvonne E. Arnold et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Real Time Evolution of Liquid Crystalline Nanostructure during the Digestion of Formulation Lipids Using Synchrotron Small-Angle X-ray Scattering
- (2011) Dallas B. Warren et al. LANGMUIR
- Excipient-Mediated Supersaturation Stabilization in Human Intestinal Fluids
- (2011) Jan Bevernage et al. MOLECULAR PHARMACEUTICS
- Biorelevant in vitro dissolution testing of products containing micronized or nanosized fenofibrate with a view to predicting plasma profiles
- (2010) Daniel Juenemann et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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- Biorelevant Media Simulating Fed State Intestinal Fluids: Colloid Phase Characterization and Impact on Solubilization Capacity
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- Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies
- (2010) Karen Kleberg et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Design of Lipid-Based Formulations for Oral Administration of Poorly Water-Soluble Drugs: Precipitation of Drug after Dispersion of Formulations in Aqueous Solution
- (2009) Kazi Mohsin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Review of the most common pre-processing techniques for near-infrared spectra
- (2009) Åsmund Rinnan et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Quantitative Application of in Situ ATR-FTIR and Raman Spectroscopy in Crystallization Processes
- (2008) Jeroen Cornel et al. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
- Characterization and Optimization of AMG 517 Supersaturatable Self‐Emulsifying Drug Delivery System (S‐SEDDS) for Improved Oral Absorption
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- Colloidal Structures in Media Simulating Intestinal Fed State Conditions with and Without Lipolysis Products
- (2008) Dimitrios G. Fatouros et al. PHARMACEUTICAL RESEARCH
- Biopharmaceutical challenges associated with drugs with low aqueous solubility—The potential impact of lipid-based formulations
- (2007) C.M. O'Driscoll et al. ADVANCED DRUG DELIVERY REVIEWS
- Evaluation of the Impact of Surfactant Digestion on the Bioavailability of Danazol after Oral Administration of Lipidic Self-Emulsifying Formulations to Dogs
- (2007) Jean F. Cuiné et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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