Stable tumor vessel normalization with pO2 increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

(2012) Gregg L. Semenza   TRENDS IN PHARMACOLOGICAL SCIENCES

Protein Kinase C-Theta Is Required for Development of Experimental Cerebral Malaria

(2011) Mathilde Fauconnier et al.   AMERICAN JOURNAL OF PATHOLOGY

Persistent vascular normalization as an alternative goal of anti-angiogenic cancer therapy

(2011) Yasufumi Sato   CANCER SCIENCE

Myo-InositolTrisPyroPhosphate Treatment Leads to HIF-1α Suppression and Eradication of Early Hepatoma Tumors in Rats

(2011) Marc Aprahamian  et al.   CHEMBIOCHEM

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

(2011) Peter Carmeliet et al.   NATURE REVIEWS DRUG DISCOVERY

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage

(2010) Young Jun Koh et al.   CANCER CELL

Osteopontin: An Effector and an Effect of Tumor Metastasis

(2010) L. Shevde et al.   CURRENT MOLECULAR MEDICINE

Nitric oxide modulates the expression of endothelial cell adhesion molecules involved in angiogenesis and leukocyte recruitment

(2010) Aude Carreau et al.   EXPERIMENTAL CELL RESEARCH

Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment

(2010) Sophie Lorquet et al.   FASEB JOURNAL

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

(2009) A. K. Ghosh et al.   BLOOD

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling

(2009) N. Qayum et al.   CANCER RESEARCH

Prolyl Hydroxylases 2 and 3 Act in Gliomas as Protective Negative Feedback Regulators of Hypoxia-Inducible Factors

(2009) A.-T. Henze et al.   CANCER RESEARCH

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

(2009) Massimiliano Mazzone et al.   CELL

Factors Interacting with HIF-1α mRNA: Novel Therapeutic Targets

(2009) Stefanie Galban et al.   CURRENT PHARMACEUTICAL DESIGN

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

The Akt/mTOR Pathway Assures the Synthesis of HIF-1α Protein in a Glucose- and Reoxygenation-dependent Manner in Irradiated Tumors

(2008) Hiroshi Harada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Mitogen-Activated Protein Kinases Regulate Susceptibility to Ventilator-Induced Lung Injury

(2008) Tamás Dolinay et al.   PLoS One