Differences in activation of mouse hepcidin by dietary iron and parenterally administered iron dextran: compartmentalization is critical for iron sensing

Regulation of iron transport and the role of transferrin

(2011) Konstantinos Gkouvatsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Non-transferrin bound iron, cytokine activation and intracellular reactive oxygen species generation in hemodialysis patients receiving intravenous iron dextran or iron sucrose

(2011) Amy Barton Pai et al.   BIOMETALS

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice

(2011) D. Meynard et al.   BLOOD

Hepcidin and iron regulation, 10 years later

(2011) T. Ganz   BLOOD

Conditional disruption of mouse HFE2 gene: Maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin

(2011) Konstantinos Gkouvatsos et al.   HEPATOLOGY

Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

(2011) Emilio Ramos et al.   HEPATOLOGY

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

(2011) Elena Corradini et al.   HEPATOLOGY

Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice

(2011) Giada Sebastiani et al.   Metallomics

Accelerated CCl4-Induced Liver Fibrosis in Hjv-/- Mice, Associated with an Oxidative Burst and Precocious Profibrogenic Gene Expression

(2011) Giada Sebastiani et al.   PLoS One

Clinical Use of Intravenous Iron: Administration, Efficacy, and Safety

(2011) M. Auerbach et al.   Hematology-American Society of Hematology Education Program

Iron Homeostasis and the Inflammatory Response

(2010) Marianne Wessling-Resnick   Annual Review of Nutrition

Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice

(2010) T. B. Bartnikas et al.   BLOOD

Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation

(2010) M. Poli et al.   HAEMATOLOGICA

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis

(2010) John D. Ryan et al.   HEPATOLOGY

Comparison of the renal, cardiovascular and hepatic toxicity data of original intravenous iron compounds

(2010) J. E. Toblli et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression

(2009) K. Mleczko-Sanecka et al.   BLOOD

Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes

(2009) G. Ramey et al.   HAEMATOLOGICA

Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload

(2009) Daniel F. Wallace et al.   HEPATOLOGY

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

Oxidative Stress and Iron Homeostasis: Mechanistic and Health Aspects

(2008) Dimitrios Galaris et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity

(2008) Kouichi Miura et al.   HEPATOLOGY