Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity

Rapamycin prevents the onset of insulin-dependent diabetes mellitus (IDDM) in NOD mice

(2010) W. L. BAEDER et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue

(2010) V. P. Houde et al.   DIABETES

Can Biogerontologists and Geriatricians Unite to Apply Aging Science to Health Care in the Decade Ahead?

(2010) D. Hamerman   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

TOR and ageing: a complex pathway for a complex process

(2010) M. A. McCormick et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease

(2010) Patricia Spilman et al.   PLoS One

Exocytosis of Insulin

(2009) Aldo Rozzo et al.   Annals of the New York Academy of Sciences

Long-term Administration of Rapamycin Reduces Adiposity, but Impairs Glucose Tolerance in High-Fat Diet-fed KK/HlJ Mice

(2009) Geng-Ruei Chang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Evaluating the glucose tolerance test in mice

(2008) Sofianos Andrikopoulos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Phosphorylation of IRS proteins, insulin action, and insulin resistance

(2008) Sigalit Boura-Halfon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

mTOR Inhibition by Rapamycin Prevents  -Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

(2008) M. Fraenkel et al.   DIABETES

Epidermal growth factor increases insulin secretion and lowers blood glucose in diabetic mice

(2008) H. Y. Lee et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sirolimus Is Associated with New-Onset Diabetes in Kidney Transplant Recipients

(2008) O. Johnston et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Impairments in glucose tolerance can have a negative impact on cognitive function: A systematic research review

(2008) Daniel J. Lamport et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Rapamycin Impairs β-Cell Proliferation In Vivo

(2008) E. Zahr et al.   TRANSPLANTATION PROCEEDINGS