Discovery and Optimization of 1,3,4-Trisubstituted-pyrazolone Derivatives as Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonists

Title
Discovery and Optimization of 1,3,4-Trisubstituted-pyrazolone Derivatives as Novel, Potent, and Nonsteroidal Farnesoid X Receptor (FXR) Selective Antagonists
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 16, Pages 7037-7053
Publisher
American Chemical Society (ACS)
Online
2012-08-04
DOI
10.1021/jm3002718

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