Review
Materials Science, Multidisciplinary
Xin Li, Luyao Sun, Peng Zhang, Yang Wang
Summary: Biofilms are formed by microorganisms as a protective survival state to resist antimicrobial agents and host immune responses. They pose a serious threat to human health, especially in medical device-associated infections, and traditional antimicrobial agents are ineffective. New treatment strategies are urgently needed to address biofilm infections.
Review
Fisheries
Le Thanh Dien, Thao Phuong Huynh Ngo, Thao V. Nguyen, Pattanapon Kayansamruaj, Krishna R. Salin, Chadag Vishnumurthy Mohan, Channarong Rodkhum, Ha Thanh Dong
Summary: Inland aquaculture, particularly in low and middle-income countries, plays a crucial role in global food security, but its sustainable development is hindered by disease epidemics, especially those caused by bacteria such as Aeromonas species. This article provides an overview of motile Aeromonas infections, antibiotic use, and antimicrobial resistance, as well as non-antibiotic approaches to control these infections. It discusses the current state of knowledge, limitations, and future research perspectives, including vaccines, microencapsulated synbiotics, exogenous metabolites, and novel lytic bacteriophage cocktails.
REVIEWS IN AQUACULTURE
(2022)
Review
Biochemistry & Molecular Biology
Karthik Vivekanandhan, Poornima Shanmugam, Hamed Barabadi, Vigneshwaran Arumugam, Dharun Daniel Raj Daniel Paul Raj, Manikandan Sivasubramanian, Subbaiya Ramasamy, Krishnan Anand, Pandi Boomi, Balakumar Chandrasekaran, Selvaraj Arokiyaraj, Muthupandian Saravanan
Summary: COVID-19 has emerged rapidly and disrupted immunization services, causing fear among people worldwide. Research suggests that antiviral drugs like remdesivir, favipiravir, and peptide-based vaccines may be potential candidates for treating SARS-CoV-2, but clinical trials are crucial for validation.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
Article
Chemistry, Medicinal
Jeffrey A. Dewey, Cleimence Delalande, Saara-Anne Azizi, Vivian Lu, Dionysios Antonopoulos, Gyorgy Babnigg
Summary: This article reviews the identification methods and strategies of small-molecule molecular glues and introduces the classification of currently approved glues. The importance of factors such as experimental conditions, software packages, and genetic tools is highlighted, and the curation of this method hopes to inspire diverse research efforts targeting a multitude of human diseases.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Marine & Freshwater Biology
Donia M. Osman, Wenke Yuan, Soha Shabaka, Muthii Patrick Nyaga, Jun Geng, Yongxiang Yu, Yuyi Yang
Summary: Plastics are widely distributed in the environment and have potential harm to living systems. However, research on the threat of micro/nanoplastics to aquatic plants is lacking. This review summarizes current research progress and emphasizes the need for future research.
AQUATIC TOXICOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Apurva Pandey, Eszter Boros
Summary: Medicinal chemists have been working on the efficient eradication of life-threatening bacterial infections for several decades, especially in response to the emergence of multi-drug resistance of pathogenic bacteria. With better understanding of nutrient acquisition and metabolism at the host-pathogen interface, new drug targets are emerging, including processes related to metal homeostasis. Opportunities for medicinal inorganic chemists to selectively alter or disrupt these processes for bacteriostatic or bacteriotoxic effects are being explored.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Biochemistry & Molecular Biology
Michele Pompilio, Ioannis Ierides, Franco Cacialli
Summary: There is a growing interest in (semi)transparent photovoltaics (sTPVs) due to the limitations of traditional opaque devices and the need for innovative applications. High conversion efficiency and aesthetically pleasing design are important requirements for these applications. Biomimetic approaches, such as moth-eye inspired structures and beetle-inspired tunable devices, show promise in improving transparent and semi-transparent photovoltaic cells. Future developments may focus on bio-inspired and potentially bio-compatible sTPVs.
Editorial Material
Biochemistry & Molecular Biology
Carl T. Bergstrom
Summary: Authors of biomedical research should provide clear and accurate information to society, and actively combat misinformation and disinformation.
Review
Oncology
Ali Zarrabi, David Perrin, Mahboubeh Kavoosi, Micah Sommer, Serap Sezen, Parvaneh Mehrbod, Bhavya Bhushan, Filip Machaj, Jakub Rosik, Philip Kawalec, Saba Afifi, Seyed Mohammadreza Bolandi, Peiman Koleini, Mohsen Taheri, Tayyebeh Madrakian, Marek J. Los, Benjamin Lindsey, Nilufer Cakir, Atefeh Zarepour, Kiavash Hushmandi, Ali Fallah, Bahattin Koc, Arezoo Khosravi, Mazaher Ahmadi, Susan Logue, Gorka Orive, Stevan Pecic, Joseph W. Gordon, Saeid Ghavami
Summary: Rhabdomyosarcoma is a rare cancer that affects skeletal muscle, primarily in children and young adults. The treatment strategies for this disease include multi-agent chemotherapies following surgical resection and radiotherapy. This review provides a detailed clinical understanding of rhabdomyosarcoma, including its classification, diagnosis, and treatment strategies. The impact of apoptosis, macro-autophagy, and the unfolded protein response on chemotherapy response is discussed. Additionally, the use of in vivo mouse and zebrafish models and in vitro three-dimensional bioengineering models for screening future therapeutic approaches and promoting muscle regeneration is explored.
Review
Medicine, General & Internal
Stephane Heymans, Neal K. Lakdawala, Carsten Tschoepe, Karin Klingel
Summary: Dilated cardiomyopathy is a condition characterized by ventricular dilatation or systolic dysfunction. It can be caused by genetic or acquired factors, such as infections, toxins, and cancer treatment. Diagnostic tests and therapeutic approaches should consider both genetic and acquired factors.
Review
Biochemistry & Molecular Biology
Ugur Sener, Michael W. Ruff, Jian L. Campian
Summary: Glioblastoma is the most common malignant brain tumor, and immunotherapy approaches for its treatment are still challenging, although multiple studies are underway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Social Issues
Deniz Cemiloglu, Mohamed Basel Almourad, John McAlaney, Raian Ali
Summary: The concept of digital addiction has gained popularity in recent years, leading to a call for solutions to combat it, particularly among adolescents. Various countermeasures have been proposed, including psycho-social, software mediated, pharmacological, and combined approaches. While these countermeasures have shown effectiveness in reducing addictive digital use, inconsistent conceptualization of digital addiction and methodological weaknesses require further attention in future studies.
TECHNOLOGY IN SOCIETY
(2022)
Review
Microbiology
Alexandra L. Krause, Timothy P. Stinear, Ian R. Monk
Summary: This review highlights the lag in molecular biology research on Enterococcus faecalis and Enterococcus faecium compared to other Gram-positive pathogens and discusses methods to overcome barriers in DNA transfer. Improving transformation techniques will expedite our understanding of these important pathogens.
FEMS MICROBIOLOGY REVIEWS
(2022)
Review
Medicine, General & Internal
Pranav Rajpurkar, Matthew P. Lungren
Summary: This article examines the advantages and limitations of current clinical radiologic AI systems, new clinical workflows, and the potential effect of generative AI and large multimodal foundation models.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Review
Green & Sustainable Science & Technology
Jaana Raisanen, Arto Ojala, Tero Tuovinen
Summary: The sharing economy offers solutions to sustainability challenges by promoting resource sharing and reuse, creating new income opportunities, and fostering social connections. Trust is crucial in this economy, and lack of trust can hinder its development. Platform developers and managers can utilize the proposed model to identify and address trust issues.
JOURNAL OF CLEANER PRODUCTION
(2021)
