Genetic variation at theFADS1-FADS2gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement

Intake levels of dietary long-chain PUFAs modify the association between genetic variation inFADSand LDL-C

(2012) S. Hellstrand et al.   JOURNAL OF LIPID RESEARCH

Effect of low doses of long-chain n−3 PUFAs on endothelial function and arterial stiffness: a randomized controlled trial

(2011) Thomas AB Sanders et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults

(2011) Diana M. Merino et al.   MOLECULAR GENETICS AND METABOLISM

Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

(2011) Rozenn N. Lemaitre et al.   PLoS Genetics

Dietary n−3 and n−6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study

(2010) Yingchang Lu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effect of changing the amount and type of fat and carbohydrate on insulin sensitivity and cardiovascular risk: the RISCK (Reading, Imperial, Surrey, Cambridge, and Kings) trial

(2010) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk

(2010) Carolina Moltó-Puigmartí et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study

(2010) Vera Zietemann et al.   BRITISH JOURNAL OF NUTRITION

Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism

(2010) Eva Lattka et al.   CURRENT OPINION IN LIPIDOLOGY

A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle

(2010) Kazuhiro Nakayama et al.   HUMAN GENETICS

Single nucleotide polymorphisms in theFADSgene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios

(2010) Szilvia Bokor et al.   JOURNAL OF LIPID RESEARCH

A commonFADS2promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1

(2009) E. Lattka et al.   JOURNAL OF LIPID RESEARCH

Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study

(2009) Toshiko Tanaka et al.   PLoS Genetics

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

(2009) Daniel I. Chasman et al.   PLoS Genetics

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes

(2008) Peter Rzehak et al.   BRITISH JOURNAL OF NUTRITION

Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation

(2008) Lin Xie et al.   JOURNAL OF NUTRITION

SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease

(2008) Giovanni Malerba et al.   LIPIDS

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS