Cytokine crowdsourcing: multicellular production of TH 17-associated cytokines

Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases

(2014) N.-E. Serriari et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer

(2014) Pin Wu et al.   IMMUNITY

The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-γ-Producing T Helper 17 Cells

(2014) Yan Wang et al.   IMMUNITY

Gata3drives development of RORγt+group 3 innate lymphoid cells

(2014) Nicolas Serafini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autocrine Regulation of IL-21 Production in Human T Lymphocytes

(2014) F. Caprioli et al.   JOURNAL OF IMMUNOLOGY

The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex

(2014) J. F. Wright et al.   JOURNAL OF IMMUNOLOGY

Reprogrammed FoxP3+ T Regulatory Cells Become IL-17+ Antigen-Specific Autoimmune Effectors In Vitro and In Vivo

(2014) S. Radhakrishnan et al.   JOURNAL OF IMMUNOLOGY

IL-17A Inhibits the Expansion of IL-17A-Producing T Cells in Mice through "Short-Loop" Inhibition via IL-17 Receptor

(2014) E. Smith et al.   JOURNAL OF IMMUNOLOGY

Check MAIT

(2014) L. Gapin   JOURNAL OF IMMUNOLOGY

IL-22 Is Essential for Lung Epithelial Repair following Influenza Infection

(2013) Derek A. Pociask et al.   AMERICAN JOURNAL OF PATHOLOGY

The study of the ratio and distribution of Th17 cells and Tc17 cells in asthmatic patients and the mouse model

(2013) Kaiyan Li   ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY

Th9 cells: differentiation and disease

(2013) Mark H. Kaplan   IMMUNOLOGICAL REVIEWS

Th17 cell development: from the cradle to the grave

(2013) Luis A. Zúñiga et al.   IMMUNOLOGICAL REVIEWS

Interleukin-22 produced by alveolar macrophages during activation of the innate immune response

(2013) Marit Hansson et al.   INFLAMMATION RESEARCH

TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis

(2013) Esben Gjerløff Wedebye Schmidt et al.   INFLAMMATORY BOWEL DISEASES

Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

(2013) Stefanie Kirchberger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of interleukin-17 during lymphocytic bronchiolitis in lung transplant patients

(2013) Stijn E. Verleden et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Adoptive Transfer of Tc1 or Tc17 Cells Elicits Antitumor Immunity against Established Melanoma through Distinct Mechanisms

(2013) Y. Yu et al.   JOURNAL OF IMMUNOLOGY

Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease

(2013) M A van Leeuwen et al.   Mucosal Immunology

Interleukin-23 is sufficient to induce rapid de novo gut tumorigenesis, independent of carcinogens, through activation of innate lymphoid cells

(2013) I H Chan et al.   Mucosal Immunology

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

The transcription factor T-bet is essential for the development of NKp46+ innate lymphocytes via the Notch pathway

(2013) Lucille C Rankin et al.   NATURE IMMUNOLOGY

Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses

(2013) Keiji Hirota et al.   NATURE IMMUNOLOGY

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(2013) Rafael A Cubas et al.   NATURE MEDICINE

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The transcription factor Th-POK negatively regulates Th17 differentiation in V 14i NKT cells

(2012) I. Engel et al.   BLOOD

Development and function of murine ROR t+ iNKT cells are under TGF-  signaling control

(2012) C. Havenar-Daughton et al.   BLOOD

Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia

(2012) Ping Cheng et al.   BMC IMMUNOLOGY

Depletion of neutrophils in a protective model of pulmonary cryptococcosis results in increased IL-17A production by gamma/delta T cells

(2012) Karen L Wozniak et al.   BMC IMMUNOLOGY

Brodalumab and ixekizumab, anti-interleukin-17-receptor antibodies for psoriasis: a critical appraisal

(2012) Ph. I. Spuls et al.   BRITISH JOURNAL OF DERMATOLOGY

Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22

(2012) Hartmann Raifer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17-producing γδ T cells and innate lymphoid cells

(2012) Caroline E. Sutton et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD8+ T Cells That Produce Interleukin-17 Regulate Myeloid-Derived Suppressor Cells and Are Associated With Survival Time of Patients With Gastric Cancer

(2012) Yuan Zhuang et al.   GASTROENTEROLOGY

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells

(2012) Enrico Girardi et al.   IMMUNOLOGICAL REVIEWS

Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection

(2012) Christophe Paget et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZBTB7B (Th-POK) Regulates the Development of IL-17-Producing CD1d-Restricted Mouse NKT Cells

(2012) A. Enders et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Inflammation Induced by Subacute Ozone Is Augmented in Adiponectin-Deficient Mice: Role of IL-17A

(2012) D. I. Kasahara et al.   JOURNAL OF IMMUNOLOGY

The  -Glucan Receptor Dectin-1 Promotes Lung Immunopathology during Fungal Allergy via IL-22

(2012) L. M. Lilly et al.   JOURNAL OF IMMUNOLOGY

Multiple Redundant Effector Mechanisms of CD8+ T Cells Protect against Influenza Infection

(2012) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

Modulation of Innate Host Factors by Mycobacterium avium Complex in Human Macrophages Includes Interleukin 17

(2012) N. Vazquez et al.   JOURNAL OF INFECTIOUS DISEASES

Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies

(2012) Mark F. Maurer et al.   mAbs

Th17 Cell Enhances CD8 T-Cell Cytotoxicity via IL-21 Production in Emphysema Mice

(2012) Min-Chao Duan et al.   MEDIATORS OF INFLAMMATION

Close link between development and function of gamma−delta T cells

(2012) Kensuke Shibata   MICROBIOLOGY AND IMMUNOLOGY

IL-22 from conventional NK cells is epithelial regenerative and inflammation protective during influenza infection

(2012) P Kumar et al.   Mucosal Immunology

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

The role of IL-17-secreting mast cells in inflammatory joint disease

(2012) Tony J. Kenna et al.   Nature Reviews Rheumatology

Marking and Quantifying IL-17A-Producing Cells In Vivo

(2012) April E. Price et al.   PLoS One

Runx1 and Runx3 Are Involved in the Generation and Function of Highly Suppressive IL-17-Producing T Regulatory Cells

(2012) Lequn Li et al.   PLoS One

Expression of ROR t Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer

(2012) N. R. Blatner et al.   Science Translational Medicine

INTERLEUKIN-22 MODULATES GUT EPITHELIAL AND IMMUNE BARRIER FUNCTIONS FOLLOWING ACUTE ALCOHOL EXPOSURE AND BURN INJURY

(2012) Juan L. Rendon et al.   SHOCK

Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines

(2012) Hiroshi Watarai et al.   PLOS BIOLOGY

Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4+ T Cells

(2012) Som Gowda Nanjappa et al.   PLoS Pathogens

Emerging Functions of RANKL in Lymphoid Tissues

(2012) Christopher G. Mueller et al.   Frontiers in Immunology

Mapping of NKp46+ Cells in Healthy Human Lymphoid and Non-Lymphoid Tissues

(2012) Elena Tomasello et al.   Frontiers in Immunology

The Th17 Pathway in Cystic Fibrosis Lung Disease

(2011) Hui-Leng Tan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dual Role of IL-22 in Allergic Airway Inflammation and its Cross-talk with IL-17A

(2011) Anne-Gaelle Besnard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Characterization of IL-17A Expression in Patients with Chronic Rhinosinusitis with Nasal Polyps

(2011) Xiao-Dan Jiang et al.   American Journal of Rhinology & Allergy

Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease

(2011) Sara Bogaert et al.   BMC IMMUNOLOGY

Regulation of interleukin-10 and interleukin-22 expression in T helper cells

(2011) Sascha Rutz et al.   CURRENT OPINION IN IMMUNOLOGY

Caspase-1-processed IL-1 family cytokines play a vital role in driving innate IL-17

(2011) Lara S. Dungan et al.   CYTOKINE

CD4+Foxp3+ regulatory T cells suppress γδ T-cell effector functions in a model of T-cell-induced mucosal inflammation

(2011) Ekaterina Yurchenko et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

(2011) Shingo Nakayamada et al.   IMMUNITY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Interleukin-23 and T helper 17-type responses in intestinal inflammation: from cytokines to T-cell plasticity

(2011) Peter J. Morrison et al.   IMMUNOLOGY

Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

(2011) Jessica L. Werner et al.   INFECTION AND IMMUNITY

Differential Role of the Interleukin-17 Axis and Neutrophils in Resolution of Inhalational Anthrax

(2011) Kévin Garraud et al.   INFECTION AND IMMUNITY

Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands

(2011) Cristiano Rumio et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Memory/effector (CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22–dependent intestinal pathology

(2011) Masahito Kamanaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease

(2011) Alessandra Geremia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Invariant NKT cells are required for airway inflammation induced by environmental antigens

(2011) Gerhard Wingender et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

(2011) Carmine Stolfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Generation of Colitogenic Th17 CD4 T Cells Is Enhanced by IL-17+    T Cells

(2011) J.-s. Do et al.   JOURNAL OF IMMUNOLOGY

Prostaglandin I 2 Promotes the Development of IL-17–Producing γδ T Cells That Associate with the Epithelium during Allergic Lung Inflammation

(2011) Zeina Jaffar et al.   JOURNAL OF IMMUNOLOGY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

Outbreaks of Mycobacterium Tuberculosis MDR Strains Induce High IL-17 T-Cell Response in Patients With MDR Tuberculosis That Is Closely Associated With High Antigen Load

(2011) Juan I. Basile et al.   JOURNAL OF INFECTIOUS DISEASES

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22

(2011) Gregory F Sonnenberg et al.   NATURE IMMUNOLOGY

B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

(2011) Irene Puga et al.   NATURE IMMUNOLOGY

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

(2011) Pheh-Ping Chang et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner

(2011) Irah L King et al.   NATURE IMMUNOLOGY

The Transcription Factor PU.1 Regulates γδ T Cell Homeostasis

(2011) Rukhsana Jabeen et al.   PLoS One

Increased natural killer T-like cells are a major source of pro-inflammatory cytokines and granzymes in lung transplant recipients

(2011) GREG HODGE et al.   RESPIROLOGY

Resolution of Allergic Airway Inflammation and Airway Hyperreactivity Is Mediated by IL-17–producing γδT Cells

(2010) Jenna R. Murdoch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Interleukin-22 genetic polymorphisms and risk of colon cancer

(2010) Cheryl L. Thompson et al.   CANCER CAUSES & CONTROL

Microbial Colonization Drives Expansion of IL-1 Receptor 1-Expressing and IL-17-Producing γ/δ T Cells

(2010) Jinyou Duan et al.   Cell Host & Microbe

Interleukin 17-Producing γδ T Cells Increased in Patients with Active Pulmonary Tuberculosis

(2010) Meiyu Peng et al.   Cellular & Molecular Immunology

Identification of Cells Expressing IL-17A and IL-17F in the Lungs of Patients With COPD

(2010) Amanda Eustace et al.   CHEST

Interleukin-22: A cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection

(2010) Ellen Witte et al.   CYTOKINE & GROWTH FACTOR REVIEWS

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

(2010) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Regulatory Cells Maintain Intestinal Homeostasis by Suppressing γδ T Cells

(2010) Sung-Gyoo Park et al.   IMMUNITY

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

(2010) Gregory F. Sonnenberg et al.   IMMUNITY

γδ T cells protect against lung fibrosis via IL-22

(2010) Philip L. Simonian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-7 and IL-15 independently program the differentiation of intestinal CD3−NKp46+cell subsets from Id2-dependent precursors

(2010) Naoko Satoh-Takayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

(2010) Gregory F. Sonnenberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-1 -Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-Producing Cells

(2010) L. Li et al.   JOURNAL OF IMMUNOLOGY

Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung

(2010) Y. Okamoto Yoshida et al.   JOURNAL OF IMMUNOLOGY

Foxp3+ IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer

(2010) Shaobo Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

(2010) Sofia Buonocore et al.   NATURE

Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue–inducer cell and NK cell lineages

(2010) Parinaz Aliahmad et al.   NATURE IMMUNOLOGY

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

(2010) Shinichiro Sawa et al.   SCIENCE

Stability of the Regulatory T Cell Lineage in Vivo

(2010) Y. P. Rubtsov et al.   SCIENCE

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

A T Cell-Dependent Mechanism for the Induction of Human Mucosal Homing Immunoglobulin A-Secreting Plasmablasts

(2009) Melissa Dullaers et al.   IMMUNITY

T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

(2009) Natalia Martin-Orozco et al.   IMMUNITY

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Anti-Inflammatory Role of IL-17 in Experimental Autoimmune Uveitis

(2009) Y. Ke et al.   JOURNAL OF IMMUNOLOGY

The Atypical Chemokine Receptor D6 Contributes to the Development of Experimental Colitis

(2009) Y. Bordon et al.   JOURNAL OF IMMUNOLOGY

The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

(2009) N. Satoh-Takayama et al.   JOURNAL OF IMMUNOLOGY

The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

(2009) Antonella Di Cesare et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

(2009) Xuyu Zhou et al.   NATURE IMMUNOLOGY

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Thymic self-reactivity selects natural interleukin 17–producing T cells that can regulate peripheral inflammation

(2009) Benjamin R Marks et al.   NATURE IMMUNOLOGY

Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice

(2008) Reiko Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Murine NKT cells produce Th17 cytokine interleukin-22

(2008) Megumi Goto et al.   CELLULAR IMMUNOLOGY

Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

(2008) Yongpeng Gu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

DC activated via dectin-1 convert Treg into IL-17 producers

(2008) Fabiola Osorio et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

(2008) J Dambacher et al.   GUT

Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease

(2008) Lauren A. Zenewicz et al.   IMMUNITY

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

(2008) Hiroaki Takatori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 produced by Paneth cells drives TNF-induced shock

(2008) Nozomi Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+T cells

(2008) Masaki Tajima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Mouse segmental duplication and copy number variation

(2008) Xinwei She et al.   NATURE GENETICS

Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin

(2008) Carmelo Luci et al.   NATURE IMMUNOLOGY

RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells

(2008) Stephanie L Sanos et al.   NATURE IMMUNOLOGY

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

(2008) Tom Cupedo et al.   NATURE IMMUNOLOGY

IL-17 attenuates the anti-apoptotic effects of GM-CSF in human neutrophils

(2007) Stéphane Dragon et al.   MOLECULAR IMMUNOLOGY