The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia

(2017) Masafumi Seki et al.   NATURE GENETICS

Identification of a genetically defined ultra-high-risk group in relapsed pediatric T-lymphoblastic leukemia

(2017) P Richter-Pechańska et al.   Blood Cancer Journal

Transcriptional Regulator CNOT3 Defines an Aggressive Colorectal Cancer Subtype

(2016) Paloma Cejas et al.   CANCER RESEARCH

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia

(2016) R. La Starza et al.   HAEMATOLOGICA

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia

(2016) R. La Starza et al.   HAEMATOLOGICA

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

(2015) C. Vicente et al.   HAEMATOLOGICA

CNOT3 contributes to early B cell development by controllingIghrearrangement andp53mRNA stability

(2015) Takeshi Inoue et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Non-coding recurrent mutations in chronic lymphocytic leukaemia

(2015) Xose S. Puente et al.   NATURE

CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins

(2015) Toru Suzuki et al.   Scientific Reports

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia

(2015) C. Vicente et al.   HAEMATOLOGICA

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia

(2014) A. Dagklis et al.   HAEMATOLOGICA

Stability of mRNA influences osteoporotic bone mass via CNOT3

(2014) C. Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated systems genetics screen reveals the transcriptional structure of inherited predisposition to metastatic disease

(2013) F. Faraji et al.   GENOME RESEARCH

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

DAVID-WS: a stateful web service to facilitate gene/protein list analysis

(2012) X. Jiao et al.   BIOINFORMATICS

Tristetraprolin Impairs Myc-Induced Lymphoma and Abolishes the Malignant State

(2012) Robert J. Rounbehler et al.   CELL

Alterations in the ribosomal machinery in cancer and hematologic disorders

(2012) Niraj Shenoy et al.   Journal of Hematology & Oncology

Architecture of the Nuclease Module of the Yeast Ccr4-Not Complex: the Not1-Caf1-Ccr4 Interaction

(2012) Jérôme Basquin et al.   MOLECULAR CELL

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

(2012) Kim De Keersmaecker et al.   NATURE GENETICS

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex

(2012) Alain-Pierre Petit et al.   NUCLEIC ACIDS RESEARCH

Obesity resistance and increased hepatic expression of catabolism-related mRNAs inCnot3+/−mice

(2011) Masahiro Morita et al.   EMBO JOURNAL

The Ccr4–Not complex

(2011) Martine A. Collart et al.   GENE

CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

(2011) Kentaro Ito et al.   GENES TO CELLS

The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability

(2011) Kentaro Ito et al.   Protein & Cell

A Global In Vivo Drosophila RNAi Screen Identifies NOT3 as a Conserved Regulator of Heart Function

(2010) G. Gregory Neely et al.   CELL

Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia

(2010) Daniel J Hodson et al.   NATURE IMMUNOLOGY

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

(2009) G. Hu et al.   GENES & DEVELOPMENT

Acute Lymphoblastic Leukemia-associated JAK1 Mutants Activate the Janus Kinase/STAT Pathway via Interleukin-9 Receptor α Homodimers

(2009) Tekla Hornakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY