Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia

Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1

(2015) Ameya Champhekar et al.   GENES & DEVELOPMENT

Mutational landscape and clonal architecture in grade II and III gliomas

(2015) Hiromichi Suzuki et al.   NATURE GENETICS

Integrated molecular analysis of adult T cell leukemia/lymphoma

(2015) Keisuke Kataoka et al.   NATURE GENETICS

Integrated genetic and epigenetic analysis defines novel molecular subgroups in rhabdomyosarcoma

(2015) Masafumi Seki et al.   Nature Communications

PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway

(2014) J Zhou et al.   LEUKEMIA

Architecture of a lymphomyeloid developmental switch controlled by PU.1, Notch and Gata3

(2013) M. M. Del Real et al.   DEVELOPMENT

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

(2013) T Haferlach et al.   LEUKEMIA

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Integrated molecular analysis of clear-cell renal cell carcinoma

(2013) Yusuke Sato et al.   NATURE GENETICS

An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data

(2013) Yuichi Shiraishi et al.   NUCLEIC ACIDS RESEARCH

FLT3 Mutations in Early T-Cell Precursor ALL Characterize a Stem Cell Like Leukemia and Imply the Clinical Use of Tyrosine Kinase Inhibitors

(2013) Martin Neumann et al.   PLoS One

Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM

(2012) T. Isoda et al.   BLOOD

Dynamic Transformations of Genome-wide Epigenetic Marking and Transcriptional Control Establish T Cell Identity

(2012) Jingli A. Zhang et al.   CELL

The molecular basis of T cell acute lymphoblastic leukemia

(2012) Pieter Van Vlierberghe et al.   JOURNAL OF CLINICAL INVESTIGATION

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Prognostic relevance of RUNX1 mutations in T-cell acute lymphoblastic leukemia

(2011) V. Grossmann et al.   HAEMATOLOGICA

ETV6mutations in early immature human T cell leukemias

(2011) Pieter Van Vlierberghe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Surprising new roles for PU.1 in the adaptive immune response

(2010) Sebastian Carotta et al.   IMMUNOLOGICAL REVIEWS

PHF6 mutations in T-cell acute lymphoblastic leukemia

(2010) Pieter Van Vlierberghe et al.   NATURE GENETICS

WT1 mutations in T-ALL

(2009) V. Tosello et al.   BLOOD

New insights to the MLL recombinome of acute leukemias

(2009) C Meyer et al.   LEUKEMIA

Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c

(2009) Sandra Stehling-Sun et al.   NATURE IMMUNOLOGY

Immunophenotyping parameters as prognostic factors in T-acute leukemia patients

(2009) O. BABUSIKOVA et al.   NEOPLASMA

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system

(2008) Peter Laslo et al.   SEMINARS IN IMMUNOLOGY