Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances

Insulin Resistance in Nonalcoholic Fatty Liver Disease

(2010) E. Bugianesi et al.   CURRENT PHARMACEUTICAL DESIGN

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Patatin-like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease

(2010) Devanshi Seth et al.   HEPATOLOGY

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

(2010) Felix Stickel et al.   HEPATOLOGY

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Acetate, the key modulator of inflammatory responses in acute alcoholic hepatitis

(2010) Stuart F. W. Kendrick et al.   HEPATOLOGY

Mortality rate of alcoholic liver disease and risk of hospitalization for alcoholic liver cirrhosis, alcoholic hepatitis and alcoholic liver failure in Australia between 1993 and 2005

(2010) W. Liang et al.   INTERNAL MEDICINE JOURNAL

Leptin Promotes the Myofibroblastic Phenotype in Hepatic Stellate Cells by Activating the Hedgehog Pathway

(2010) Steve S. Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria

(2010) Wolfgang Sieghart et al.   JOURNAL OF HEPATOLOGY

Blockade of interaction of α9 integrin with its ligands hinders the formation of granulation in cutaneous wound healing

(2010) Yosuke Nakayama et al.   LABORATORY INVESTIGATION

Alcohol, Signaling, and ECM Turnover

(2009) Devanshi Seth et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Role for hedgehog pathway in regulating growth and function of invariant NKT cells

(2009) Wing-Kin Syn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease

(2009) Wing–Kin Syn et al.   GASTROENTEROLOGY

Genome-Wide Association Analysis in Primary Sclerosing Cholangitis

(2009) Tom H. Karlsen et al.   GASTROENTEROLOGY

Epithelial-to-mesenchymal transitions in the liver

(2009) Steve S. Choi et al.   HEPATOLOGY

Interleukin-17-producing CD4+ T cells increase with severity of liver damage in patients with chronic hepatitis B

(2009) Ji-Yuan Zhang et al.   HEPATOLOGY

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production

(2009) Alessia Omenetti et al.   HEPATOLOGY

Signalling pathways in alcohol-induced liver inflammation

(2009) Pranoti Mandrekar et al.   JOURNAL OF HEPATOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Variant in PNPLA3 is associated with alcoholic liver disease

(2009) Chao Tian et al.   NATURE GENETICS

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Alcohol-induced Modulation of Signaling Pathways in Liver Parenchymal and Nonparenchymal Cells: Implications for Immunity

(2009) Bharath Nath et al.   SEMINARS IN LIVER DISEASE

No Role of Matrixmetalloproteinase-3 Genetic Promoter Polymorphism 1171 as a Risk Factor for Cirrhosis in Alcoholic Liver Disease

(2008) Felix Stickel et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Population-Based Genome-wide Association Studies Reveal Six Loci Influencing Plasma Levels of Liver Enzymes

(2008) Xin Yuan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alcohol and lipid metabolism

(2008) Margaret Sozio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Adventures of Sonic Hedgehog in Development and Repair. II. Sonic hedgehog and liver development, inflammation, and cancer

(2008) Alessia Omenetti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Osteopontin Promotes Vascular Endothelial Growth Factor Dependent Breast Tumor Growth and Angiogenesis via Autocrine and Paracrine Mechanisms

(2008) G. Chakraborty et al.   CANCER RESEARCH

Evaluation of the transforming growth factor β1 codon 25 (Arg→Pro) polymorphism in alcoholic liver disease

(2008) Christoph H. Österreicher et al.   CYTOKINE

Silencing a Killer Among Us: Ethanol Impairs Immune Surveillance of Activated Stellate Cells by Natural Killer Cells

(2008) Gavin E. Arteel   GASTROENTEROLOGY

Disease Progression in Chronic Hepatitis C: Modifiable and Nonmodifiable Factors

(2008) Sharif B. Missiha et al.   GASTROENTEROLOGY

Cell Type–Dependent Pro- and Anti-Inflammatory Role of Signal Transducer and Activator of Transcription 3 in Alcoholic Liver Injury

(2008) Norio Horiguchi et al.   GASTROENTEROLOGY

Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage

(2008) Steven Dooley et al.   GASTROENTEROLOGY

Accumulation of Hedgehog-Responsive Progenitors Parallels Alcoholic Liver Disease Severity in Mice and Humans

(2008) Youngmi Jung et al.   GASTROENTEROLOGY

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes

(2008) Anna Ludovica Fracanzani et al.   HEPATOLOGY

Peroxisome proliferator-activated receptor-δ induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice

(2008) Xiaomei Qin et al.   HEPATOLOGY

The interleukin-17 pathway is involved in human alcoholic liver disease

(2008) Arnaud Lemmers et al.   HEPATOLOGY

Adiponectin and alcoholic fatty liver disease

(2008) Christopher Q. Rogers et al.   IUBMB LIFE

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

New role of plasminogen activator inhibitor-1 in alcohol-induced liver injury

(2008) Gavin E Arteel   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Quantifying the risk for alcohol-use and alcohol-attributable health disorders: Present findings and future research needs

(2008) Ting-Kai Li   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Fat paradox of steatohepatitis

(2008) Hidekazu Tsukamoto et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Transforming growth factor-β and hepatocyte transdifferentiation in liver fibrogenesis

(2008) Nadja M Meindl-Beinker et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Direct effects of alcohol on hepatic fibrinolytic balance: Implications for alcoholic liver disease

(2008) Devanshi Seth et al.   JOURNAL OF HEPATOLOGY

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Mechanisms of Disease Progression in Nonalcoholic Fatty Liver Disease

(2008) Janice Jou et al.   SEMINARS IN LIVER DISEASE

Potential Relationship between Hepatobiliary Osteopontin and Peroxisome Proliferator–Activated Receptor α Expression following Ethanol-Associated Hepatic Injury In Vivo and In Vitro

(2008) Jin-Hyung Lee et al.   TOXICOLOGICAL SCIENCES

Interplay between oxidative stress and immunity in the progression of alcohol-mediated liver injury

(2008) Matteo Vidali et al.   TRENDS IN MOLECULAR MEDICINE

Abrogation of the Antifibrotic Effects of Natural Killer Cells/Interferon-γ Contributes to Alcohol Acceleration of Liver Fibrosis

(2007) Won–Il Jeong et al.   GASTROENTEROLOGY

Alcohol induced hepatic fibrosis: Role of acetaldehyde

(2007) Tommaso Mello et al.   MOLECULAR ASPECTS OF MEDICINE

Oxidative mechanisms in the pathogenesis of alcoholic liver disease

(2007) Emanuele Albano   MOLECULAR ASPECTS OF MEDICINE