Molecular interactions, bioavailability and cellular mechanisms of angiotensin converting enzyme inhibitory (ACEi) peptides

In silico analysis and molecular docking study of angiotensin I-converting enzyme inhibitory peptides from smooth-hound viscera protein hydrolysates fractionated by ultrafiltration

(2018) Ola Abdelhedi et al.   FOOD CHEMISTRY

Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro , ex vivo and in vivo transport models

(2017) John P. Gleeson et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Transepithelial Transport of YWDHNNPQIR and Its Metabolic Fate with Cytoprotection against Oxidative Stress in Human Intestinal Caco-2 Cells

(2017) Feiran Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transport Study of Egg-Derived Antihypertensive Peptides (LKP and IQW) Using Caco-2 and HT29 Coculture Monolayers

(2017) Qingbiao Xu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transport of a Novel Angiotensin-I-Converting Enzyme Inhibitory Peptide Ala-His-Leu-Leu Across Human Intestinal Epithelial Caco-2 Cells

(2017) Ying Li et al.   JOURNAL OF MEDICINAL FOOD

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

(2017) Bin Zhou et al.   LANCET

Revisiting the mechanisms of ACE inhibitory peptides from food proteins

(2017) Jianping Wu et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) differentially modulate angiotensin II effects on vascular smooth muscle cells

(2017) Subhadeep Chakrabarti et al.   Journal of Functional Foods

Soy protein-derived ACE-inhibitory peptide LSW (Leu-Ser-Trp) shows anti-inflammatory activity on vascular smooth muscle cells

(2017) Qinlu Lin et al.   Journal of Functional Foods

Angiotensin I–converting enzyme–inhibitory peptides from bovine collagen: insights into inhibitory mechanism and transepithelial transport

(2016) Yu Fu et al.   FOOD RESEARCH INTERNATIONAL

Digestion and absorption of an egg white ACE-inhibitory peptide in human intestinal Caco-2 cell monolayers

(2016) Long Ding et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Modulatory Effects of Egg White Ovotransferrin-Derived Tripeptide IRW (Ile-Arg-Trp) on Vascular Smooth Muscle Cells against Angiotensin II Stimulation

(2016) Wang Liao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transepithelial transport of dry-cured ham peptides with ACE inhibitory activity through a Caco-2 cell monolayer

(2016) Marta Gallego et al.   Journal of Functional Foods

A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives

(2016) Abdul Muheem et al.   SAUDI PHARMACEUTICAL JOURNAL

Dietary bioactive peptides: Human studies

(2015) Dominique Bouglé et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Transport of Antihypertensive Peptide RVPSL, Ovotransferrin 328–332, in Human Intestinal Caco-2 Cell Monolayers

(2015) Long Ding et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Food-Originating ACE Inhibitors, Including Antihypertensive Peptides, as Preventive Food Components in Blood Pressure Reduction

(2014) Anna Iwaniak et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Peptidomics for discovery, bioavailability and monitoring of dairy bioactive peptides

(2014) Laura Sánchez-Rivera et al.   FOOD RESEARCH INTERNATIONAL

Molecular Targets of Antihypertensive Peptides: Understanding the Mechanisms of Action Based on the Pathophysiology of Hypertension

(2014) Kaustav Majumder et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bioavailability and Kinetics of the Antihypertensive Casein-Derived Peptide HLPLP in Rats

(2014) Laura Sánchez-Rivera et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transport of Egg White ACE-Inhibitory Peptide, Gln-Ile-Gly-Leu-Phe, in Human Intestinal Caco-2 Cell Monolayers with Cytoprotective Effect

(2014) Long Ding et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Food-Derived Bioactive Peptides on Inflammation and Oxidative Stress

(2014) Subhadeep Chakrabarti et al.   Biomed Research International

LC–MS/MS coupled with QSAR modeling in characterising of angiotensin I-converting enzyme inhibitory peptides from soybean proteins

(2013) Yuchen Gu et al.   FOOD CHEMISTRY

Bioavailability of antihypertensive lactoferricin B-derived peptides: Transepithelial transport and resistance to intestinal and plasma peptidases

(2013) Ricardo Fernández-Musoles et al.   INTERNATIONAL DAIRY JOURNAL

Transport of IRW, an Ovotransferrin-Derived Antihypertensive Peptide, in Human Intestinal Epithelial Caco-2 Cells

(2013) Satyanarayana Bejjani et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structure and Activity Study of Egg Protein Ovotransferrin Derived Peptides (IRW and IQW) on Endothelial Inflammatory Response and Oxidative Stress

(2013) Kaustav Majumder et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Catalytic Mechanism of Angiotensin-Converting Enzyme and Effects of the Chloride Ion

(2013) Chunchun Zhang et al.   JOURNAL OF PHYSICAL CHEMISTRY B

New Frontiers in the Intrarenal Renin-Angiotensin System: A Critical Review of Classical and New Paradigms

(2013) Jia L. Zhuo et al.   Frontiers in Endocrinology

Three key proteases – angiotensin-I-converting enzyme (ACE), ACE2 and renin – within and beyond the renin-angiotensin system

(2012) Cuie Guang et al.   Archives of Cardiovascular Diseases

Molecular mechanism of the interactions between inhibitory tripeptides and angiotensin-converting enzyme

(2012) Min Zhou et al.   BIOPHYSICAL CHEMISTRY

Predictive modelling of angiotensin converting enzyme inhibitory dipeptides

(2012) Roseanne Norris et al.   FOOD CHEMISTRY

Antihypertensive peptides from food proteins: a review

(2012) Daniel Martínez-Maqueda et al.   Food & Function

Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides

(2012) Geoffrey Masuyer et al.   Scientific Reports

QSAR-aided in silico approach in evaluation of food proteins as precursors of ACE inhibitory peptides

(2011) Yuchen Gu et al.   FOOD RESEARCH INTERNATIONAL

The (193-209) 17-residues peptide of bovine β-casein is transported through Caco-2 monolayer

(2010) Daniela Regazzo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Arachin derived peptides as selective angiotensin I-converting enzyme (ACE) inhibitors: Structure–activity relationship

(2010) V.K. Jimsheena et al.   PEPTIDES

Inflammatory cytokines in vascular dysfunction and vascular disease

(2009) Alexander H. Sprague et al.   BIOCHEMICAL PHARMACOLOGY

Transepithelial Transport Characteristics of the Antihypertensive Peptide, Lys-Val-Leu-Pro-Val-Pro, in Human Intestinal Caco-2 Cell Monolayers

(2009) Haiyan SUN et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

(2008) Thomas Münzel et al.   ANNALS OF MEDICINE

Transport of Val-Leu-Pro-Val-Pro in Human Intestinal Epithelial (Caco-2) Cell Monolayers

(2008) Lin Lei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Angiotensin-I converting enzyme (ACE) inhibitory mechanism of tripeptides containing aromatic residues

(2008) Yuka Kobayashi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Studies on the molecular recognition between bioactive peptides and angiotensin-converting enzyme

(2008) A.S. Pina et al.   JOURNAL OF MOLECULAR RECOGNITION

Transepithelial transport across Caco-2 cell monolayers of antihypertensive egg-derived peptides. PepT1-mediated flux of Tyr-Pro-Ile

(2008) Marta Miguel et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Angiotensin-Converting Enzyme C-Terminal Catalytic Domain Is the Main Site of Angiotensin I Cleavage In Vivo

(2007) Sebastien Fuchs et al.   HYPERTENSION

Bioavailability of the antihypertensive peptide LHLPLP: Transepithelial flux of HLPLP

(2007) Ana Quirós et al.   INTERNATIONAL DAIRY JOURNAL