Article
Polymer Science
Le Chang, Cong Wang, Shuang Han, Xiaolong Sun, Feng Xu
Summary: This article presents a smart hydrogel system that can undergo structural transformations under neutral aqueous conditions, regulating stiffness and properties through dynamic covalent bonding. With good biocompatibility, this system shows great potential in biomedical applications such as tissue engineering and cell therapy.
Article
Materials Science, Multidisciplinary
Xiaoye Huang, Ruobing Yu
Summary: Superhydrophobic surfaces with high oil-repellency were prepared by adding unmodified nano-SiO2 and micron-SiO2 to fluorinated epoxy, showing good liquid repellency when the amounts of nano-SiO2 and micro-SiO2 are equal. These superhydrophobic coatings exhibit excellent mechanical and chemical durability, self-cleaning performance, corrosion resistance, and anti-icing properties, making them suitable for a wide range of applications on various substrates.
Article
Chemistry, Applied
Chen Wang, Junzhu Yang, Yuan Lu
Summary: Click chemistry is a rapid and reliable method for synthesizing a variety of molecules, emphasizing the development of new combinatorial chemistry methods based on the synthesis of carbon-heteroatomic bonds and the simple and efficient acquisition of molecular diversity through these reactions. Click chemistry methods are advancing towards precision, simplicity, and high returns, especially in producing polymer materials and some bright biomedical applications.
CHINESE JOURNAL OF CATALYSIS
(2023)
Article
Polymer Science
Yijie Jin, Manjusha Joshi, Takuma Araki, Naofumi Kamimura, Eiji Masai, Masaya Nakamura, Tsuyoshi Michinobu
Summary: Novel biomass-based polymers based on PDC were synthesized using Cu(I)-catalyzed azide-alkyne cycloaddition and fully characterized. These PDC-based polymers exhibited high thermal stability and strong adhesive properties to various metal plates, with the highest adhesion to copper. The addition of triazole ring improved the adhesive ability and selectivity of the PDC-based polymers to copper, enhancing their versatility as adhesives.
Article
Chemistry, Multidisciplinary
Dong-Dong Liang, Sidharam P. Pujari, Muthusamy Subramaniam, Maarten Besten, Han Zuilhof
Summary: The SuFEx reaction between chiral di-sulfonimidoyl fluorides and diphenols is used to produce polysulfonimidates with configurational backbone chirality, allowing for the efficient synthesis of tailor-made chiral polymers with precise properties.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biochemistry & Molecular Biology
Anurag Noonikara-Poyil, Alvaro Munoz-Castro, H. V. Rasika Dias
Summary: This study describes the isolation and full characterization of a thermally stable, copper(I) acetylene complex using a highly fluorinated bis(pyrazolyl)borate ligand support, as well as the details of a related copper(I) complex. Raman data show significant red-shifts in C equivalent to C stretch of different alkynes bound to copper(I), with computational analysis indicating that the interaction is primarily of the electrostatic character. The study also highlights the catalytic activity of a mononuclear copper complex in [3 + 2] cycloadditions and compares its effectiveness with a trinuclear copper catalyst.
Article
Chemistry, Multidisciplinary
Leona L. Rodrigues, Aaron S. Micallef, Michael C. Pfrunder, Vinh X. Truong, John C. McMurtrie, Tim R. Dargaville, Anja S. Goldmann, Florian Feist, Christopher Barner-Kowollik
Summary: A highly efficient ligation system based on visible light-induced rearrangement was introduced, generating a thiophenol for rapid thiol-Michael additions without the need for additives. The self-catalyzed ligation through pyridine mediated deprotonation of the photochemically generated thiophenol was described, leading to additive-free thiol-Michael reactions. The study explored various reaction conditions, solvents, and substrates, showcasing excellent end group fidelity in polymer modification.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Lina Mao, Xiao Ren, Bang Feng, Yunlong Zhang, Jing Zhang, Wei Huang
Summary: A new A(A') + B3 approach based on sydnone-maleimide double cycloaddition (SMDC) was investigated for synthesizing hyperbranched polyimides (HBPIs). The method effectively avoided gelation and improved the degree of branching. By adjusting the monomer concentration and feeding modes, HBPIs with moderate molecular weight and low polydispersity could be obtained. Furthermore, the as-synthesized HBPIs exhibited good solubility and thermal stability.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Multidisciplinary Sciences
Xu Qiu, Yueqian Sang, Hao Wu, Xiao-Song Xue, Zixi Yan, Yachong Wang, Zengrui Cheng, Xiaoyang Wang, Hui Tan, Song Song, Guisheng Zhang, Xiaohui Zhang, K. N. Houk, Ning Jiao
Summary: Synthetic chemistry is primarily focused on forming carbon-carbon bonds, but the development of methods for selective carbon-carbon bond cleavage is a significant challenge. These methods have potential applications in synthesis, coal liquefaction, petroleum cracking, polymer degradation, and biomass conversion.
Article
Chemistry, Multidisciplinary
Aman Kumar, Kashmiri Lal, Nisha Poonia, Ashwani Kumar, Anil Kumar
Summary: A diverse series of imine linked 1,2,3-triazole hybrids were synthesized via Cu(I)-promoted click reaction, and their structures were characterized using various spectral techniques. Among them, 7d exhibited the highest antimicrobial activity against R. oryzae and S. aureus. Docking studies revealed that some triazole hybrids showed high potency towards E. coli DNA gyrase and C. albicans sterol 14-alpha demethylase.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Polymer Science
Fatih Biryan, Hilal Celik, Eray Caliskan, Kenan Koran
Summary: In this study, cinnamic acid side chain bearing polymer and its ferrocene-modified polymer were synthesized. The addition of a ferrocene unit improved the optical and electrical properties of the target polymer. The fabricated diode showed rectifier behavior and exhibited unique electrical properties due to the characteristics of the organic polymer.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Polymer Science
Aarti Singh, Aakanksha Agarwal, Arnab Chakraborty, Rohit Bhardwaj, Soumyaditya Sutradhar, Amit Kumar Mittal, Satyendra Kumar Rajput, Mukul Gupta, Devalina Ray, Monalisa Mukherjee
Summary: The fabrication of crystalline polymers is challenging but intellectually stimulating. Amphiphilic block copolymers self-assemble in water to form vesicle-like structures with curved interfaces, which are commonly found in shape-translational symmetry incommensurate crystals. By forming a crystalline structure, the mechanical properties of the polymeric system are improved.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Zhiyu Hu, Hongting Pu
Summary: A feasible method for preparing single-chain polymer nanoparticles (SCNPs) carrying metal catalysts through the intramolecular collapse of linear polymers is proposed. These nanoparticles exhibit better catalytic properties for the click reaction of alkyne and azide.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Stephanie Vanslambrouck, Raphael Riva, Bernard Ucakar, Veronique Preat, Mick Gagliardi, Daniel G. M. Molin, Philippe Lecomte, Christine Jerome
Summary: PEG-b-PPE block copolymer nanoparticles are potential drug carriers with poor water solubility. A strategy to enhance drug loading capacity by increasing the lipophilicity of the PPE block was investigated. Synthesis of a PEG-b-PPE copolymer with pendant vinyl groups and modification with thiols bearing long alkyl chains or tocopherol showed promising results in improving drug loading efficiency.
Article
Polymer Science
Huan Liu, Shihong Cheng, Yadong Yang, Chunlin Wang, Shijiang Zhu, Fuchun Zhao
Summary: A new type of fluorinated polyisoprene was tailored by introducing fluoroalkyl side chains onto the backbone chains via a facile procedure. The film of fluorinated polyisoprene demonstrated improved environmental endurance, with significantly increased water contact angle and UV reflectivity.
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Wen-Qi Xu, Xiu-Hua Xu, Feng-Ling Qing
CHINESE JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Jun Yang, Shengqing Zhu, Fang Wang, Feng-Ling Qing, Lingling Chu
Summary: This new method involves the reaction of TMSCF2H with styrenes and vinyl trifluoroborates to directly prepare CF2H-alkenes with excellent functional group compatibility. Additionally, this approach can be applied to a variety of substrates for radical difluoromethylation reactions, providing a versatile platform for constructing diverse C-CF2H bonds.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Organic
Yao Ouyang, Chao-Lai Tong, Xiu-Hua Xu, Feng-Ling Qing
Summary: The first copper and zinc copromoted trifluoromethylation using trifluoromethanesulfonic anhydride (Tf2O) as a trifluoromethylating reagent has been developed, affording bromo(chloro)trifluoromethylated products in good yields. CuX2 plays a dual role as the catalyst and halide source, whereas 2,2'-bipyridine acts as both the activation reagent and ligand.
Article
Chemistry, Inorganic & Nuclear
Ya-Ling Liu, Xiao-Lei Zhu, Yangen Huang, Feng-Ling Qing, Xiu-Hua Xu
Summary: An efficient radical coupling method for arylthiodifluoroacetic acids and ethynylbenziodoxolone (EBX) reagents has been developed, providing moderate to good yields of ArSCF2-substituted alkynes. The synthetic utility of this protocol was demonstrated by transforming the resulting products into other ArSCF2-substituted alkynes and alkenes.
JOURNAL OF FLUORINE CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Chen-Chen Hu, Wei-Qiang Hu, Xiu-Hua Xu, Feng-Ling Qing
Summary: A mild and efficient method for regioselective C-H fluoromethylation of heteroaryl N-oxides using (fluoromethyl)triphenylphosphonium iodide is presented. This reaction yields a series of C2-fluoromethylated pyridine and quinoline derivatives in moderate to good yields when LiOt-Bu is used as the base and HMSO as the solvent, extending the synthetic applications of (fluoromethyl)triphenylphosphonium iodide.
JOURNAL OF FLUORINE CHEMISTRY
(2021)
Article
Chemistry, Organic
Feng Chen, Xiu-Hua Xu, Feng-Ling Qing
Summary: This study presents a direct and efficient method for the synthesis of 1-bromo-1-fluoroalkanes from unactivated alkenes and dibromofluoromethane under photoredox catalysis. The key to the success of these reactions lies in the appropriate choice of photoredox catalyst. The prepared 1-bromo-1-fluoroalkanes can be further transformed into various fluorine-containing compounds.
Article
Chemistry, Multidisciplinary
Jia-Yi Shou, Xiu-Hua Xu, Feng-Ling Qing
Summary: Pentafluorosulfanyl chloride (SF5Cl) is commonly used in organic synthesis, but its preparation often involves hazardous reagents and specialized equipment. Researchers have developed a safe and practical method to prepare a stable and easy-to-handle solution of SF5Cl without the need for gas-phase reagents, demonstrating its potential through synthetic applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Chao-Lai Tong, Xiu-Hua Xu, Feng-Ling Qing
Summary: Efficient heptafluoroisopropoxylation reactions were achieved through the invention of a series of redox-active N-OCF(CF3)(2) reagents. Various substrates can undergo direct heptafluoroisopropoxylation to yield products in moderate to excellent yields.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Xiaolei Zhu, Yangen Huang, Xiuhua Xu, Fengling Qing
Summary: An iron-catalyzed coupling reaction between difluoroenol silyl ethers and cyclobutanone oxime esters has been described, providing a convenient access to various gem-difluoromethylenated ketonitriles in moderate to good yields. The transformations of the resulting products to other fluorine-containing compounds are also documented.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Yao Ouyang, Xiu-Hua Xu, Feng-Ling Qing
Summary: The study introduces a novel electrochemical reaction method for the direct trifluoromethoxylation of aromatics, providing a valuable structural motif for drug discovery.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Xian Zhao, Xiaoliang Feng, Fan Chen, Shengqing Zhu, Feng-Ling Qing, Lingling Chu
Summary: A metallaphotoredox-catalyzed strategy for the aminocarbonylation of alkynes with amines and CO has been developed. This method allows for selective synthesis of alpha,beta-unsaturated amides and a sequential four-component hydroaminocarbonylation/radical alkylation, demonstrating great potential in the selective and divergent functionalization of alkynes. Preliminary mechanistic studies suggest a photoinduced oxidative insertion of aniline and CO into nickel followed by a migratory insertion of (carbamoyl)nickel species may be involved.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Juan Wang, Shuai Liu, Yangen Huang, Xiu-Hua Xu, Feng-Ling Qing
Summary: The first C-H trifluoroethylamination of heteroarenes using previously unknown N-trifluoroethyl hydroxylamine reagents was achieved under photoredox catalyzed conditions. Various heteroarenes, such as indoles, benzofurans, and benzothiophenes, were smoothly converted to trifluoroethylaminated products with moderate to high yields and excellent regioselectivity.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Shuai Liu, Yangen Huang, Juan Wang, Feng-Ling Qing, Xiu-Hua Xu
Summary: This study reports a method for the design and synthesis of novel N-Cbz- and N-Boc-N-trifluoromethyl hydroxylamine reagents using silver-mediated oxidative trifluoromethylation. These reagents have been successfully applied to incorporate a NCF3 moiety into commonly used unsaturated substrates, enabling efficient and regioselective C-H trifluoromethylamination. Additionally, a variety of substrates can undergo tandem trifluoromethylamination/functionalization to deliver structurally diverse N-trifluoromethyl aliphatic and heteroaromatic amines.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Inorganic & Nuclear
Yao-Yao Zhu, Shuai Liu, Yangen Huang, Feng-Ling Qing, Xiu-Hua Xu
Summary: The photoredox catalyzed difluoro(phenylthio)methylation of 2,3-allenoic acids with {difluoro(phenylthio)methyl}triphenylphosphonium triflate was investigated. A series of previously unknown 4-difluoro(phenylthio)methylated butenolides were synthesized through tandem radical difluoro(phenylthio)methylation/intramolecular cyclization.
JOURNAL OF FLUORINE CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Xian Zhao, Shengqing Zhu, Feng-Ling Qing, Lingling Chu
Summary: This method utilizes a photoredox/nickel dual catalysis to achieve the reductive hydrobenzylation of alkynes and benzyl chlorides, providing facile access to important 1,1-disubstituted olefins. The reaction proceeds under mild conditions and is compatible with a wide range of aryl and alkyl alkynes as well as chlorides.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Xianda Wu, Minghong Chen, Shuiyun Zheng, Fu-Sheng He, Jie Wu
Summary: Here, we report a new method for synthesizing sulfilimines through an iron-catalyzed reaction between sulfenamides and 2,2,2-trifluor-diazoethane. This protocol features operational simplicity, mild conditions, and can be conducted in open air, providing a facile approach to trifloromethylated sulfilimines in moderate to good yields.
JOURNAL OF FLUORINE CHEMISTRY
(2024)
Article
Chemistry, Inorganic & Nuclear
Ita Hajdin, Romana Pajkert, Haibo Mei, Jianlin Han, Gerd-Volker Roeschenthaler
Summary: A catalyst- and solvent-free 1,3-dipolar cycloaddition reaction using a bench-stable diazo reagent has been developed to obtain a series of novel 3H-pyrazoles bearing difluoromethyl phosphonate unit in moderate-to-excellent yields. This method provides an efficient and easy route to synthesize valuable compounds.
JOURNAL OF FLUORINE CHEMISTRY
(2024)
