MK5 activatesRagtranscription via Foxo1 in developing B cells

FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination

(2012) Alabbas Alkhatib et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PRAK Suppresses Oncogenic ras -Induced Hematopoietic Cancer Development by Antagonizing the JNK Pathway

(2012) Naoto Yoshizuka et al.   MOLECULAR CANCER RESEARCH

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation

(2012) Kyoko Ochiai et al.   NATURE IMMUNOLOGY

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

(2012) R. Mansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

V(D)J Recombination: Mechanisms of Initiation

(2011) David G. Schatz et al.   Annual Review of Genetics

FoxO family members in cancer

(2011) Yuqing Zhang et al.   CANCER BIOLOGY & THERAPY

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

Multilineage Priming of Enhancer Repertoires Precedes Commitment to the B and Myeloid Cell Lineages in Hematopoietic Progenitors

(2011) Elinore M. Mercer et al.   IMMUNITY

Identification of the Atypical MAPK Erk3 as a Novel Substrate for p21-activated Kinase (Pak) Activity

(2011) Alina De La Mota-Peynado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gfi1b negatively regulatesRagexpression directly and via the repression ofFoxO1

(2011) Danae Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis

(2011) N. Yoshizuka et al.   MOLECULAR AND CELLULAR BIOLOGY

The MK5/PRAK Kinase and Myc Form a Negative Feedback Loop that Is Disrupted during Colorectal Tumorigenesis

(2011) Theresia R. Kress et al.   MOLECULAR CELL

Inactivation of Rheb by PRAK-mediated phosphorylation is essential for energy-depletion-induced suppression of mTORC1

(2011) Min Zheng et al.   NATURE CELL BIOLOGY

Mitogen-activated protein kinase p38 and MK2, MK3 and MK5: Ménage à trois or ménage à quatre?

(2010) Alexey Shiryaev et al.   CELLULAR SIGNALLING

Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling Pathway

(2010) Paul Déléris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5

(2009) Sergiy Kostenko et al.   CELLULAR SIGNALLING

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of Immunoglobulin Light-Chain Recombination by the Transcription Factor IRF-4 and the Attenuation of Interleukin-7 Signaling

(2008) Kristen Johnson et al.   IMMUNITY

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

(2008) Hart S Dengler et al.   NATURE IMMUNOLOGY

FOXO-binding partners: it takes two to tango

(2008) K E van der Vos et al.   ONCOGENE

The FoxO code

(2008) D R Calnan et al.   ONCOGENE

RNAi screening for kinases and phosphatases identifies FoxO regulators

(2008) J. Mattila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification

(2008) Michael M. Brent et al.   STRUCTURE