Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

EBF1 Is Essential for B-Lineage Priming and Establishment of a Transcription Factor Network in Common Lymphoid Progenitors

(2014) S. Zandi et al.   JOURNAL OF IMMUNOLOGY

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T Cell Acute Lymphoblastic Leukemia

(2012) Takaomi Sanda et al.   CANCER CELL

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo

(2012) S. Zandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors

(2011) P. Tsapogas et al.   BLOOD

Control of the Embryonic Stem Cell State

(2011) Richard A. Young   CELL

Multilineage Priming of Enhancer Repertoires Precedes Commitment to the B and Myeloid Cell Lineages in Hematopoietic Progenitors

(2011) Elinore M. Mercer et al.   IMMUNITY

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

(2011) E. Welinder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early B Cell Factor 1 Regulates B Cell Gene Networks by Activation, Repression, and Transcription- Independent Poising of Chromatin

(2010) Thomas Treiber et al.   IMMUNITY

Interleukin-7-induced Stat-5 Acts in Synergy with Flt-3 Signaling to Stimulate Expansion of Hematopoietic Progenitor Cells

(2010) Josefine Åhsberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

(2010) Yin C Lin et al.   NATURE IMMUNOLOGY

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity

(2009) R. Mansson et al.   BLOOD

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

(2009) M. A. Inlay et al.   GENES & DEVELOPMENT

Stepwise Activation of Enhancer and Promoter Regions of the B Cell Commitment Gene Pax5 in Early Lymphopoiesis

(2009) Thorsten Decker et al.   IMMUNITY

The cunning little vixen: Foxo and the cycle of life and death

(2009) Stephen M Hedrick   NATURE IMMUNOLOGY

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

(2008) R. Mansson et al.   BLOOD

Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages

(2008) H. Karsunky et al.   BLOOD

E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors

(2008) Sheila Dias et al.   IMMUNITY

Foxo1 directly regulates the transcription of recombination-activating genes during B cell development

(2008) Rupesh H Amin et al.   NATURE IMMUNOLOGY

Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation

(2008) Hart S Dengler et al.   NATURE IMMUNOLOGY

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5

(2008) Jagan M R Pongubala et al.   NATURE IMMUNOLOGY

Global regulatory logic for specification of an embryonic cell lineage

(2008) P. Oliveri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA