Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization

A Quantitative Trait Locus on Chromosome 4 Affects Cycling of Hematopoietic Stem and Progenitor Cells through Regulation of TGF- 2 Responsiveness

(2014) S. Avagyan et al.   JOURNAL OF IMMUNOLOGY

What does the concept of the stem cell niche really mean today?

(2012) Arthur D Lander et al.   BMC BIOLOGY

Temporal Changes in PTEN and mTORC2 Regulation of Hematopoietic Stem Cell Self-Renewal and Leukemia Suppression

(2012) Jeffrey A. Magee et al.   Cell Stem Cell

mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis

(2012) Demetrios Kalaitzidis et al.   Cell Stem Cell

Hematopoiesis: A Human Perspective

(2012) Sergei Doulatov et al.   Cell Stem Cell

The evolving concept of cancer and metastasis stem cells

(2012) Irène Baccelli et al.   JOURNAL OF CELL BIOLOGY

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Endogenous viruses: insights into viral evolution and impact on host biology

(2012) Cédric Feschotte et al.   NATURE REVIEWS GENETICS

Slow Disease Progression in a C57BL/6 Pten -Deficient Mouse Model of Prostate Cancer

(2011) Robert U. Svensson et al.   AMERICAN JOURNAL OF PATHOLOGY

Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia

(2011) M. Bonnet et al.   BLOOD

CREB Is a Novel Nuclear Target of PTEN Phosphatase

(2011) T. Gu et al.   CANCER RESEARCH

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

p57Kip2 and p27Kip1 Cooperate to Maintain Hematopoietic Stem Cell Quiescence through Interactions with Hsc70

(2011) Peng Zou et al.   Cell Stem Cell

p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells

(2011) Akinobu Matsumoto et al.   Cell Stem Cell

Breaking the Cell Cycle of HSCs by p57 and Friends

(2011) Melania Tesio et al.   Cell Stem Cell

The hematopoietic stem cell niche

(2011) Dongsu Park   Frontiers in Bioscience-Landmark

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

(2011) Armin Ehninger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice

(2011) Matthew J. Christopher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The effect Akt2 deletion on tumor development in Pten+/− mice

(2011) P-Z Xu et al.   ONCOGENE

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species

(2010) M. M. Juntilla et al.   BLOOD

Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling

(2010) M. Tesio et al.   BLOOD

Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs

(2010) I. G. Winkler et al.   BLOOD

mTOR Activation Induces Tumor Suppressors that Inhibit Leukemogenesis and Deplete Hematopoietic Stem Cells after Pten Deletion

(2010) Jae Y. Lee et al.   Cell Stem Cell

Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases

(2010) Ana V. Miletic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeting leukemic stem cells by breaking their dormancy

(2010) Marieke Alida Gertruda Essers et al.   Molecular Oncology

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

(2009) M. G. Kharas et al.   BLOOD

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

(2008) Wei Guo et al.   NATURE

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

(2008) Keith W. Orford et al.   NATURE REVIEWS GENETICS

The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey

(2008) C B Knobbe et al.   ONCOGENE