Targeting leukemic stem cells by breaking their dormancy

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML

(2010) Yoriko Saito et al.   NATURE BIOTECHNOLOGY

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

Treatment strategies for CML

(2009) John M. Goldman   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

The Tortoise and the Hair: Slow-Cycling Cells in the Stem Cell Race

(2009) Elaine Fuchs   CELL

Stem Cell in the Adult Drosophila Hindgut: Just a Sleeping Beauty

(2009) Ting Xie   Cell Stem Cell

Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure

(2009) R. Nasr et al.   CLINICAL CANCER RESEARCH

A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell

(2009) Keisuke Ito et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Balancing dormant and self-renewing hematopoietic stem cells

(2009) Anne Wilson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A pilot study of continuous imatinib vs pulsed imatinib with or without G-CSF in CML patients who have achieved a complete cytogenetic response

(2009) M W Drummond et al.   LEUKEMIA

Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues

(2009) J M Goldman et al.   LEUKEMIA

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Cancer stem cells are everywhere

(2009)   NATURE MEDICINE

Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon–dependent exhaustion

(2009) Taku Sato et al.   NATURE MEDICINE

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery

(2009) Bin-Bing S. Zhou et al.   NATURE REVIEWS DRUG DISCOVERY

Estimating Dormant and Active Hematopoietic Stem Cell Kinetics through Extensive Modeling of Bromodeoxyuridine Label-Retaining Cell Dynamics

(2009) Richard C. van der Wath et al.   PLoS One

Stem cell concepts renew cancer research

(2008) J. E. Dick   BLOOD

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Recent advances in cancer stem cells

(2008) Robert W Cho et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Here, there, everywhere?

(2008) Connie J. Eaves   NATURE

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE

Mechanisms of Disease: cancer stem cells—targeting the evil twin

(2008) Andreas Trumpp et al.   Nature clinical practice. Oncology