A new ER-specific photosensitizer unravels 1O2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT

Endoplasmic Reticulum Stress in Malignancy

(2014) Hanna J. Clarke et al.   CANCER CELL

The SIRT1/HIF2  Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

(2014) C. Corbet et al.   CANCER RESEARCH

Scavenging rate constants of hydrophilic antioxidants against multiple reactive oxygen species

(2014) Yoshimi Sueishi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Antitumor Activity of 7-Aminocarboxycoumarin Derivatives, a New Class of Potent Inhibitors of Lactate Influx but Not Efflux

(2014) N. Draoui et al.   MOLECULAR CANCER THERAPEUTICS

Stoichiometry and assembly of mTOR complexes revealed by single-molecule pulldown

(2014) Ankur Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation

(2013) E Seront et al.   BRITISH JOURNAL OF CANCER

Large-scale identification of ubiquitination sites by mass spectrometry

(2013) Namrata D Udeshi et al.   Nature Protocols

Dye Sensitizers for Photodynamic Therapy

(2013) Alexandra Ormond et al.   Materials

Cleaning Up: ER-Associated Degradation to the Rescue

(2012) Jeffrey L. Brodsky   CELL

Photoexcitation of tumor-targeted corroles induces singlet oxygen-mediated augmentation of cytotoxicity

(2012) Jae Youn Hwang et al.   JOURNAL OF CONTROLLED RELEASE

Photo-excitation of carotenoids causes cytotoxicity via singlet oxygen production

(2011) Hiroshi Yoshii et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes

(2011) Mikael Altun et al.   CHEMISTRY & BIOLOGY

Cell Death Pathways in Photodynamic Therapy of Cancer

(2011) Pawel Mroz et al.   Cancers

Inhibition of Autophagosome Formation by the Benzoporphyrin Derivative Verteporfin

(2010) Elizabeth Donohue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidation-induced intramolecular disulfide bond inactivates mitogen-activated protein kinase kinase 6 by inhibiting ATP binding

(2010) Y. Diao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the hypoxia-inducible factor (HIF) pathway in cancer

(2009) Evon Poon et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The physics, biophysics and technology of photodynamic therapy

(2008) Brian C Wilson et al.   PHYSICS IN MEDICINE AND BIOLOGY

The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

(2008) Kunio Nakatsukasa et al.   TRAFFIC