Diacerein-mediated inhibition of IL-6/IL-6R signaling induces apoptotic effects on breast cancer

Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer

(2015) Goutam Dey et al.   Scientific Reports

Self-assembled cardanol azo derivatives as antifungal agent with chitin-binding ability

(2014) Denial Mahata et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

(2014) Matjaz Rokavec et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

(2014) Gautam Sethi et al.   Molecular Cancer

Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?

(2014) K Brinkmann et al.   Cell Death & Disease

Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor–ligand complex

(2014) Jacob Lauwring Andersen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular targeting of Akt by thymoquinone promotes G1 arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells

(2013) Shashi Rajput et al.   LIFE SCIENCES

Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer

(2013) Shashi Rajput et al.   PLoS One

Role of STAT3 in Cancer Metastasis and Translational Advances

(2013) Mohammad Zahid Kamran et al.   Biomed Research International

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women

(2012) Singh Pooja et al.   CYTOKINE

Inhibition of the IL-6 signaling pathway: A strategy to combat chronic inflammatory diseases and cancer

(2012) Parvin Ataie-Kachoie et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration

(2012) Jonathan Michaud-Levesque et al.   EXPERIMENTAL CELL RESEARCH

Interleukin-6, osteopontin and Raf/MEK/ERK signaling modulate the sensitivity of human myeloma cells to alkylphosphocholines

(2012) Deyan Y. Yosifov et al.   LEUKEMIA RESEARCH

Diacerein decreases visceral pain through inhibition of glutamatergic neurotransmission and cytokine signaling in mice

(2012) Vinícius Maria Gadotti et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer

(2011) P. Venkatesan et al.   BIOMATERIALS

Celecoxib Inhibits Interleukin-6/Interleukin-6 Receptor-Induced JAK2/STAT3 Phosphorylation in Human Hepatocellular Carcinoma Cells

(2011) Y. Liu et al.   Cancer Prevention Research

Blockade of the HER Family of Receptors in the Treatment of HER2-Positive Metastatic Breast Cancer

(2011) Jasgit C. Sachdev et al.   Clinical Breast Cancer

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

(2011) Simon A. Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Soluble gp130 Regulates Prostate Cancer Invasion and Progression in an Interleukin-6 Dependent and Independent Manner

(2011) Shahrokh F. Shariat et al.   JOURNAL OF UROLOGY

Cytokine disbalance in common human cancers

(2010) Zoran Culig   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation

(2010) Alexander Plotnikov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Interleukin-6 in bone metastasis and cancer progression

(2010) Tasnim Ara et al.   EUROPEAN JOURNAL OF CANCER

Inhibition of STAT3 Signaling Blocks the Anti-apoptotic Activity of IL-6 in Human Liver Cancer Cells

(2010) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells

(2010) Siddik Sarkar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

gp130 at the nexus of inflammation, autoimmunity, and cancer

(2010) J. S. Silver et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Roles for Growth Factors in Cancer Progression

(2010) Esther Witsch et al.   PHYSIOLOGY

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

(2009) F. Colotta et al.   CARCINOGENESIS

Apratoxin A Reversibly Inhibits the Secretory Pathway by Preventing Cotranslational Translocation

(2009) Y. Liu et al.   MOLECULAR PHARMACOLOGY

Thalidomide for treatment of multiple myeloma: 10 years later

(2008) A. Palumbo et al.   BLOOD