The role of kisspeptin neurons in reproduction and metabolism

The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis

(2018) Kirsty A. Walters et al.   NEUROENDOCRINOLOGY

Female sexual behavior in mice is controlled by kisspeptin neurons

(2018) Vincent Hellier et al.   Nature Communications

Altered aspects of anxiety-related behavior in kisspeptin receptor-deleted male mice

(2018) Sarah Delmas et al.   Scientific Reports

Kisspeptin modulates sexual and emotional brain processing in humans

(2017) Alexander N. Comninos et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones

(2017) K. Ikegami et al.   JOURNAL OF NEUROENDOCRINOLOGY

Definition of the hypothalamic GnRH pulse generator in mice

(2017) Jenny Clarkson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AgRP to Kiss1 neuron signaling links nutritional state and fertility

(2017) Stephanie L. Padilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rodent Models of Non-classical Progesterone Action Regulating Ovulation

(2017) Melinda A. Mittelman-Smith et al.   Frontiers in Endocrinology

High-Fat Diet Causes Subfertility and Compromised Ovarian Function Independent of Obesity in Mice1

(2016) Malgorzata E. Skaznik-Wikiel et al.   BIOLOGY OF REPRODUCTION

Metabolism and Energy Expenditure, But Not Feeding or Glucose Tolerance, Are Impaired in Young Kiss1r KO Female Mice

(2016) Kristen P. Tolson et al.   ENDOCRINOLOGY

Diurnal regulation of hypothalamic kisspeptin is disrupted during mouse pregnancy

(2016) Cassandra C Yap et al.   JOURNAL OF ENDOCRINOLOGY

Unaltered Hypothalamic Metabolic Gene Expression inKiss1rKnockout Mice Despite Obesity and Reduced Energy Expenditure

(2016) Julie-Ann P. De Bond et al.   JOURNAL OF NEUROENDOCRINOLOGY

Visualisation ofKiss1Neurone Distribution Using a Kiss1-CRE Transgenic Mouse

(2016) S.-H. Yeo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Leptin/leptinR-kisspeptin/kiss1r-GnRH pathway reacting to regulate puberty onset during negative energy balance

(2016) Qianqian Luo et al.   LIFE SCIENCES

Effects of high-fat diet-induced obesity and diabetes on Kiss1 and GPR54 expression in the hypothalamic–pituitary–gonadal (HPG) axis and peripheral organs (fat, pancreas and liver) in male rats

(2016) M. Dudek et al.   NEUROPEPTIDES

Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice

(2016) Arnon Gal et al.   PLoS One

Positive, But Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons

(2015) Sharon L. Dubois et al.   ENDOCRINOLOGY

Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice

(2015) Shannon B. Z. Stephens et al.   ENDOCRINOLOGY

Effects of intravenous administration of neurokinin receptor subtype-selective agonists on gonadotropin-releasing hormone pulse generator activity and luteinizing hormone secretion in goats

(2015) Takashi YAMAMURA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Kisspeptin-13 enhances memory and mitigates memory impairment induced by Aβ1–42 in mice novel object and object location recognition tasks

(2015) J.H. Jiang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep

(2015) Qun Li et al.   NEUROENDOCRINOLOGY

Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion

(2015) Su Young Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period

(2015) Xiaoliang Qiu et al.   PLoS One

Estradiol modulates Kiss1 neuronal response to ghrelin

(2014) Renata Frazao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucagon Regulates Hepatic Kisspeptin to Impair Insulin Secretion

(2014) Woo-Jin Song et al.   Cell Metabolism

Obesity-Induced Hypogonadism in the Male: Premature Reproductive Neuroendocrine Senescence and Contribution of Kiss1-Mediated Mechanisms

(2014) Miguel Angel Sánchez-Garrido et al.   ENDOCRINOLOGY

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

(2014) Kristen P. Tolson et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence that Insulin Signalling in Gonadotrophin-Releasing Hormone and Kisspeptin Neurones does not Play an Essential Role in Metabolic Regulation of Fertility in Mice

(2014) M. C. Evans et al.   JOURNAL OF NEUROENDOCRINOLOGY

The Effects of Chronic Subcutaneous Administration of an Investigational Kisspeptin Analog, TAK-683, on Gonadotropin-Releasing Hormone Pulse Generator Activity in Goats

(2014) Takashi Yamamura et al.   NEUROENDOCRINOLOGY

Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes

(2013) Robert L. Goodman et al.   ENDOCRINOLOGY

Leptin Signaling in Kiss1 Neurons Arises after Pubertal Development

(2013) Roberta M. Cravo et al.   PLoS One

Spontaneous Kisspeptin Neuron Firing in the Adult Mouse Reveals Marked Sex and Brain Region Differences but No Support for a Direct Role in Negative Feedback

(2012) Simon de Croft et al.   ENDOCRINOLOGY

Balancing ovulation and anovulation: integration of the reproductive and energy balance axes by neuropeptides

(2012) J. J. Evans et al.   HUMAN REPRODUCTION UPDATE

Gonadotropin-Inhibitory Hormone Is a Hypothalamic Peptide That Provides a Molecular Switch between Reproduction and Feeding

(2012) Iain J. Clarke et al.   NEUROENDOCRINOLOGY

Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain

(2012) J. Tomikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guinea Pig Kisspeptin Neurons Are Depolarized by LeptinviaActivation of TRPC Channels

(2011) Jian Qiu et al.   ENDOCRINOLOGY

Leptin Deficiency and Diet-Induced Obesity Reduce Hypothalamic Kisspeptin Expression in Mice

(2011) Janette H. Quennell et al.   ENDOCRINOLOGY

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

(2011) Jeremy T. Smith et al.   ENDOCRINOLOGY

Ultrastructural Evidence of Kisspeptin-Gonadotrophin-Releasing Hormone (GnRH) Interaction in the Median Eminence of Female Rats: Implication of Axo-Axonal Regulation of GnRH Release

(2011) Y. Uenoyama et al.   JOURNAL OF NEUROENDOCRINOLOGY

Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility

(2011) Victor M. Navarro et al.   Nature Reviews Endocrinology

Kisspeptin Cells in the Ewe Brain Respond to Leptin and Communicate with Neuropeptide Y and Proopiomelanocortin Cells

(2010) Kathryn Backholer et al.   ENDOCRINOLOGY

Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion

(2010) Michael N. Lehman et al.   ENDOCRINOLOGY

Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons

(2010) Jose Donato et al.   JOURNAL OF CLINICAL INVESTIGATION

Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism

(2010) L.-Y. Fu et al.   JOURNAL OF NEUROSCIENCE

Neurokinin B and Dynorphin A in Kisspeptin Neurons of the Arcuate Nucleus Participate in Generation of Periodic Oscillation of Neural Activity Driving Pulsatile Gonadotropin-Releasing Hormone Secretion in the Goat

(2010) Y. Wakabayashi et al.   JOURNAL OF NEUROSCIENCE

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets

(2009) J. Vikman et al.   DIABETES OBESITY & METABOLISM

Kisspeptin Neurons in the Ovine Arcuate Nucleus and Preoptic Area Are Involved in the Preovulatory Luteinizing Hormone Surge

(2009) J. T. Smith et al.   ENDOCRINOLOGY

Distribution and Postnatal Development ofGpr54Gene Expression in Mouse Brain and Gonadotropin-Releasing Hormone Neurons

(2009) Allan E. Herbison et al.   ENDOCRINOLOGY

Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain

(2009) J. Clarkson et al.   JOURNAL OF NEUROENDOCRINOLOGY

Regulation of Kiss1 and Dynorphin Gene Expression in the Murine Brain by Classical and Nonclassical Estrogen Receptor Pathways

(2009) M. L. Gottsch et al.   JOURNAL OF NEUROSCIENCE

Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse

(2009) V. M. Navarro et al.   JOURNAL OF NEUROSCIENCE

Obesity and Its Relationship to Infertility in Men and Women

(2009) J. Ricardo Loret de Mola   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Kisspeptin Can Stimulate Gonadotropin-Releasing Hormone (GnRH) Release by a Direct Action at GnRH Nerve Terminals

(2008) Xavier d'Anglemont de Tassigny et al.   ENDOCRINOLOGY

AGPR54-Activating Mutation in a Patient with Central Precocious Puberty

(2008) Milena Gurgel Teles et al.   NEW ENGLAND JOURNAL OF MEDICINE

From KISS1 to kisspeptins: An historical perspective and suggested nomenclature

(2008) Michelle L. Gottsch et al.   PEPTIDES

Postmenopausal increase in KiSS-1, GPR54, and luteinizing hormone releasing hormone (LHRH-1) mRNA in the basal hypothalamus of female rhesus monkeys

(2008) WooRam Kim et al.   PEPTIDES