Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure
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Title
Pharmacotherapy in pregnancy; effect of ABC and SLC transporters on drug transport across the placenta and fetal drug exposure
Authors
Keywords
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Journal
JOURNAL OF DRUG TARGETING
Volume 20, Issue 9, Pages 736-763
Publisher
Informa UK Limited
Online
2012-09-20
DOI
10.3109/1061186x.2012.716847
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- (2008) D. Hirt et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2008) L. M. Aleksunes et al. DRUG METABOLISM AND DISPOSITION
- Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein
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- (2008) Bernhard Ugele et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice
- (2008) Andrew J. Lickteig et al. LIFE SCIENCES
- Metformin versus Insulin for the Treatment of Gestational Diabetes
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- (2008) Míriam Molina-Arcas et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Characterization of the Mechanism of Zidovudine Uptake by Rat Conditionally Immortalized Syncytiotrophoblast Cell Line TR-TBT
- (2008) Y. Sai et al. PHARMACEUTICAL RESEARCH
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- (2008) Qingcheng Mao PHARMACEUTICAL RESEARCH
- Maternal characteristics associated with pregnancy exposure to FDA category C, D, and X drugs in a Canadian population
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- Regulation of Protein Expression and Function of OCTN2 in Forskolin-Induced Syncytialization in BeWo Cells
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- (2007) Erik Rytting et al. BIOCHEMICAL PHARMACOLOGY
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- Determination of metformin transfer across the human placenta using a dually perfused ex vivo placental cotyledon model
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- The inhibitory effects of fluoroquinolones on l-carnitine transport in placental cell line BeWo
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- Breast Cancer Resistance Protein: Mediating the Trans-placental Transfer of Glyburide across the Human Placenta
- (2007) C. Gedeon et al. PLACENTA
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