P-glycoprotein related drug interactions: clinical importance and a consideration of disease states

Transmembrane Helix 12 Modulates Progression of the ATP Catalytic Cycle in ABCB1

(2009) Emily Crowley et al.   BIOCHEMISTRY

Enantioselective disposition of fexofenadine with the P-glycoprotein inhibitor verapamil

(2009) Takashi Sakugawa et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

ABC Efflux Pump-Based Resistance to Chemotherapy Drugs

(2009) Paul D. W. Eckford et al.   CHEMICAL REVIEWS

Rifampicin alters atorvastatin plasma concentration on the basis of SLCO1B1 521T>C polymorphism

(2009) Yi-Jing He et al.   CLINICA CHIMICA ACTA

Targeting anti-HIV drugs to the CNS

(2009) Kavitha S Rao et al.   Expert Opinion on Drug Delivery

Human Brain Imaging and Radiation Dosimetry of 11C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein

(2009) N. Seneca et al.   JOURNAL OF NUCLEAR MEDICINE

Simultaneous PET Imaging of P-Glycoprotein Inhibition in Multiple Tissues in the Pregnant Nonhuman Primate

(2009) S. Eyal et al.   JOURNAL OF NUCLEAR MEDICINE

Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition

(2009) Guido Zibell et al.   NEUROPHARMACOLOGY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein

(2008) Daniel Kurnik et al.   ANESTHESIOLOGY

Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1

(2008) Tomoko Sato et al.   BIOCHEMICAL PHARMACOLOGY

Multi-functional nanocarriers to overcome tumor drug resistance

(2008) Lara S. Jabr-Milane et al.   CANCER TREATMENT REVIEWS

Prediction of Broad Spectrum Resistance of Tumors towards Anticancer Drugs

(2008) T. Efferth et al.   CLINICAL CANCER RESEARCH

Drug–Drug Interactions Mediated Through P-Glycoprotein: Clinical Relevance and In Vitro–In Vivo Correlation Using Digoxin as a Probe Drug

(2008) KS Fenner et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients

(2008) Igor Mosyagin et al.   EPILEPSIA

Drug interaction between oral atorvastatin and verapamil in healthy subjects: effects of atorvastatin on the pharmacokinetics of verapamil and norverapamil

(2008) Dong-Hyun Choi et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

PhRMA White Paper on ADME Pharmacogenomics

(2008) J. Andrew Williams et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA

(2008) A. L. Bartels et al.   JOURNAL OF NEURAL TRANSMISSION

P-Glycoprotein Function at the Blood-Brain Barrier Imaged Using 11C-N-Desmethyl-Loperamide in Monkeys

(2008) J.-S. Liow et al.   JOURNAL OF NUCLEAR MEDICINE

Recent progresses in the experimental methods and evaluation strategies of transporter functions for the prediction of the pharmacokinetics in humans

(2008) Satoshi Kitamura et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Blood–brain barrier P-glycoprotein function is not impaired in early Parkinson's disease

(2008) A.L. Bartels et al.   PARKINSONISM & RELATED DISORDERS

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

(2008) D. S. Miller et al.   PHARMACOLOGICAL REVIEWS

A regulatory viewpoint on transporter-based drug interactions

(2008) L. Zhang et al.   XENOBIOTICA

Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption

(2007) Joseph M. Custodio et al.   ADVANCED DRUG DELIVERY REVIEWS

Effect of P‐Glycoprotein Expression Levels on the Concentration‐Dependent Permeability of Drugs to the Cell Membrane

(2007) Yoshiyuki Shirasaka et al.   JOURNAL OF PHARMACEUTICAL SCIENCES